Protein Alignment CG5535 and slc7a4

DIOPT Version :9

• Sequence 1: NP_649019.2
• Gene: CG5535 / 39990
• FlyBaseID: FBgn0036764
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_919408.2
• Gene: slc7a4 / 796100
• ZFINID: ZDB-GENE-030919-2
• Length: 677
• Species: Danio rerio
• Alignment Length: 631
• Identity: 233/631 - (36%)
• Similarity: 354/631 - (56%)
• Gaps: 64/631 - (10%)

  Fly    22 LTRKKPLEDS-NESKLAKVLSAFDLTALGIGSTLGVGVYVLAGEVSKQYAGPAVVVSFLIAAIAS 85
            |.|.|.|:|. ..:.|.:.|:..||..||:|..:|.|:|||.|.|:|..||||||:|||||.:||
Zfish    18 LNRLKTLDDDVMATSLKRCLNTVDLALLGVGGMVGSGLYVLTGTVAKDTAGPAVVISFLIAGVAS 82

  Fly    86 IFAGLCYAEFGARVPKAGSAYIYSYVTIGEFIAFLIGWNLILEYAIGSASVVKGLSTYLDQLCGN 150
            :.|.||||||||||||.||||:::||::||..|||||||:||||.||.|:|.:..|.|||.:..:
Zfish    83 LMAALCYAEFGARVPKTGSAYMFTYVSVGEIWAFLIGWNVILEYMIGGAAVARAWSGYLDSIFNH 147

  Fly   151 PMSSFLGTH-MPLNIEGMGAYPDLFAFVVTILFSLAIAVGAKESTRVNNVFTMLNLGVVLFVIIA 214
            .:.:|..:| |...:..:..||||.|..:.::.|..|:.|.:.|:.:|::|:.:::.|::|:::.
Zfish   148 RIQNFTESHVMRWEVPFLAHYPDLLAAAILLVASFFISFGVRVSSWLNHIFSAISMVVIVFILVF 212

  Fly   215 GLFKVSSSNWSIPKSQVPEGYGDGGFMPYGVSGIIKGAAVCFYGFIGFDCIATAGEEAKNPKKSI 279
            |.......|||.         .:|||.|:|:|||:.|.|.|||.|:|||.||.:.|||.||:::|
Zfish   213 GFILADPVNWSA---------REGGFAPFGLSGIMAGTATCFYAFVGFDVIAASSEEASNPQRAI 268

  Fly   280 PFAVIVSLAMIFLAYFGVSTVLTMMLPYFEQDEKAPLPHVFRINGWHVAEYVVSIGAMFGLCSSM 344
            |.|..:||.:...||..||||||:|:|:...|..:.|...|...|:..|.::|::|::..:.:.:
Zfish   269 PAATAISLGLAATAYVLVSTVLTLMVPWHTLDPNSALSDAFFRRGYSWAGFIVAVGSICAMNTVL 333

  Fly   345 MGAMFPLPRIVFAMSNDGLLFKFLGDISEKYKTPFKGTMITGMLTGILAAVFNLSQLVNMMSIGT 409
            :..:|.|||||:||:.|||.|.....::...|.|....::.|.|..|||.:|:|..||..:||||
Zfish   334 LSNLFSLPRIVYAMAEDGLFFSVFSRVNPVTKVPVIAILVFGSLMAILALIFDLEALVQFLSIGT 398

  Fly   410 LLAYSMVASCVLMLRYEVD-------------------------DRRESRIVANGRAT------- 442
            ||||:.||:.|::||::.|                         .:.:..:.||...|
Zfish   399 LLAYTFVAASVIVLRFQPDKSSGSSGAGGVKTDASSTPSGNQSGQQMDLSVAANEAQTFAQDGGE 463

  Fly   443 -------------------GLEQDRPCALWRRIFNLNGQTVPTKQTSRIVTYSVTLFSLWCMVFS 488
                               |.|:..|..|..|.....|:.:...:...:|.:||....:..:..|
Zfish   464 LKEYESFSDKLQLVERQKAGKEKRAPGMLKARWEPYLGRLLGDCEPGEVVAFSVLALMVSGVSLS 528

  Fly   489 QILTKFEEDL-ANVTSFDGIKLVLGTIPLAVLLLVISRQPTSGVKLSFKVPLVPWLPGISILINI 552
            .:|......| ..|.||..:.::...:.|..|.|:...:....:| :|:|||||::||.|||:|:
Zfish   529 AVLVFGNNQLHLPVWSFTLLLVIFSVVFLLSLALISVHEQRPNLK-TFQVPLVPFIPGFSILLNV 592

  Fly   553 YLMIKLDILTWIRFSIWIAIGLAIFLAYGIRHSRLRQREQRNNSIA 598
            :||:||..||||||::|:|.||.::..|||.||:...|||:...:|
Zfish   593 FLMLKLSPLTWIRFTVWVAAGLLVYFGYGIWHSKEGLREQQGQDVA 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5535	NP_649019.2	2A0303	20..585	CDD:273330	227/616 (37%)
		AA_permease_C	535..585	CDD:290617	29/49 (59%)
slc7a4	NP_919408.2	2A0303	11..627	CDD:273330	229/618 (37%)
		AA_permease_C	575..625	CDD:290617	29/49 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593012
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000131
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100168
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2006
SonicParanoid	1	1.000	-	-		X81
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.680