Protein Alignment CG5535 and Slc7a2

DIOPT Version :9

• Sequence 1: NP_649019.2
• Gene: CG5535 / 39990
• FlyBaseID: FBgn0036764
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_001128158.1
• Gene: Slc7a2 / 64554
• RGDID: 68387
• Length: 658
• Species: Rattus norvegicus
• Alignment Length: 672
• Identity: 285/672 - (42%)
• Similarity: 408/672 - (60%)
• Gaps: 68/672 - (10%)

  Fly    10 MPSWSVTNAFRVLTRKK--PLEDSNESKLAKVLSAFDLTALGIGSTLGVGVYVLAGEVSKQYAGP 72
            :|..:|....|.|.|:|  .|:...:|||.:.|:..||.|||:|||||.|||||||||:|..:||
  Rat     2 IPCRAVLTFTRCLIRRKIVTLDSLEDSKLCRCLTTMDLIALGVGSTLGAGVYVLAGEVAKADSGP 66

  Fly    73 AVVVSFLIAAIASIFAGLCYAEFGARVPKAGSAYIYSYVTIGEFIAFLIGWNLILEYAIGSASVV 137
            ::||||||||:||:.||||||||||||||.||||:|:|||:||..||:.||||||.|.||::||.
  Rat    67 SIVVSFLIAALASVMAGLCYAEFGARVPKTGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVA 131

  Fly   138 KGLSTYLDQLCGNPMSSFLGTHMPLNIEGMGAYPDLFAFVVTILFSLAIAVGAKESTRVNNVFTM 202
            :..|...|:|....:..|..|:..:|..|:..|||.||..:.:|.:..::.|.|||..||..||.
  Rat   132 RAWSGTFDELLNKQIGQFFKTYFKMNYTGLAEYPDFFAVCLVLLLAGLLSFGVKESAWVNKFFTA 196

  Fly   203 LNLGVVLFVIIAGLFKVSSSNWSI---------------PKSQVPEGYGDGGFMPYGVSGIIKGA 252
            :|:.|:|||::||..|.:.:||.|               |.......||.|||||||.:|.:.||
  Rat   197 INILVLLFVMVAGFVKGNVANWKISEEFLKNISASAREPPSENGTSIYGAGGFMPYGFTGTLAGA 261

  Fly   253 AVCFYGFIGFDCIATAGEEAKNPKKSIPFAVIVSLAMIFLAYFGVSTVLTMMLPYFEQDEKAPLP 317
            |.|||.|:|||||||.|||.:||:|:||..::.||.:.|:||||||..||:|:||:..|||:|||
  Rat   262 ATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYLLDEKSPLP 326

  Fly   318 HVFRINGWHVAEYVVSIGAMFGLCSSMMGAMFPLPRIVFAMSNDGLLFKFLGDISEKYKTPFKGT 382
            ..|...||..|:|||:.|::..|.:|::|::||:||:::||:.||||||.|..|:.|.|||...|
  Rat   327 VAFEYVGWGPAKYVVAAGSLCALSTSLLGSIFPMPRVIYAMAEDGLLFKCLAQINSKTKTPIIAT 391

  Fly   383 MITGMLTGILAAVFNLSQLVNMMSIGTLLAYSMVASCVLMLRYE--------------------- 426
            :.:|.:..::|.:|:|..||:|||||||:|||:||:|||:|||:
  Rat   392 LSSGAVAAVMAFLFDLKALVDMMSIGTLMAYSLVAACVLILRYQPGLCYEQPKYTPEKDILESCT 456

  Fly   427 -VDDRRESRI-VANGRATGLEQDRPCALWRRIFNLNGQTVPTKQTSRIVTYSVTLFSLWCMVFSQ 489
             ...:.||:: :..|:...|         |.:|  |...:||:|::.:|::.|...:......|.
  Rat   457 NATSKSESQVTMLQGQGFSL---------RTLF--NPSALPTRQSASLVSFLVGFLAFLIAGLSI 510

  Fly   490 ILTKFEEDLANVTSFDGIKLVLGTIPLAVLLLVISRQPTSGVKLSFKVPLVPWLPGISILINIYL 554
            :.|...:.:|.:.::....|.|..:..|.::|.|.|||.:..|::|.||.:|:||..|||:||||
  Rat   511 LTTYGVQAIARLEAWSLALLALFLVLCAAVILTIWRQPQNQQKVAFMVPFLPFLPAFSILVNIYL 575

  Fly   555 MIKLDILTWIRFSIWIAIGLAIFLAYGIRHS---RLRQREQRNNSIAMMRDCSNSALLGGQENS- 615
            |::|...||:|||||:.:|..|:.|||||||   ..|..|:..:.      |.::.....:|.|
  Rat   576 MVQLSADTWVRFSIWMVLGFLIYFAYGIRHSLEGNPRDEEEDEDV------CPDNVNAAAEEKSA 634

  Fly   616 KYSNE-------VPLILMHSTS 630
            ..:|:       :|.||...||
  Rat   635 MQANDHHQRNLSLPFILHEKTS 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5535	NP_649019.2	2A0303	20..585	CDD:273330	270/604 (45%)
		AA_permease_C	535..585	CDD:290617	29/49 (59%)
Slc7a2	NP_001128158.1	2A0303	5..608	CDD:273330	273/613 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351189
Domainoid	1	1.000	457	1.000	Domainoid score	I470
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	534	1.000	Inparanoid score	I1161
OMA	1	1.010	-	-		QHG53617
OrthoDB	1	1.010	-	-		D421901at33208
OrthoFinder	1	1.000	-	-		FOG0000131
OrthoInspector	1	1.000	-	-		mtm8968
orthoMCL	1	0.900	-	-		OOG6_100168
Panther	1	1.100	-	-	O	PTHR43243
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X81
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.910