DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5535 and slc7a6

DIOPT Version :9

Sequence 1:	NP_649019.2	Gene:	CG5535 / 39990	FlyBaseID:	FBgn0036764	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	XP_005166451.1	Gene:	slc7a6 / 57957	ZFINID:	ZDB-GENE-000607-21	Length:	494	Species:	Danio rerio

Alignment Length:	529	Identity:	126/529 - (23%)
Similarity:	218/529 - (41%)	Gaps:	100/529 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 KPLEDSNESKLAKVLSAFDLTALGIGSTLGVGVYVLAGEV---SKQYAGPAVVVSFLIAAIASIF 87
            ||.|   ..:|.|.:|..:..:|.:|:.:|.|::|....|   |..| |.::|: :.|..|.|:.
Zfish    22 KPRE---SMQLKKEISLLNGVSLIVGNMIGSGIFVSPKGVLIYSASY-GLSLVI-WAIGGIFSVV 81

  Fly    88 AGLCYAEFGARVPKAGSAYIYSYVTIGEFIAFLIGWN--LILEYAIGSASVVKGLSTYLDQ---- 146
            ..|||||.|..:.|:|::|.|...:.|.||||:..|.  ||:| ....|.:....:.||.|
Zfish    82 GALCYAELGTTITKSGASYAYILESFGGFIAFIRLWTSLLIIE-PTSQAVIAITFANYLVQPLFP 145

  Fly   147 LCGNPMSSFLGTHMPLNIEGMGAYPDLFAFVVTILFSLAIAVGAKESTRVNNVFTMLNLGVVLFV 211
            .|..|.|:                ..|.|.....|.:...:...|..|||.:|||...:..::.:
Zfish   146 TCEPPYSA----------------SRLIAAACICLLTFINSAYVKWGTRVQDVFTYAKVLALIVI 194

  Fly   212 IIAGLFKVSSSNWSIPKSQVPEGYGDGGFMPYGVSGIIKGAAVCFYGFIGFDCIATAGEEAKNPK 276
            ||.|:.|: ...::|   ...:.:......|.|::..:..|   .:.:.|:|.:....||.|||:
Zfish   195 IITGIVKL-CQGFTI---NFEDSFQGSSRDPGGIALALYSA---LFSYSGWDTLNFVTEEIKNPE 252

  Fly   277 KSIPFAVIVSLAMIFLAYFGVSTVLTMMLPYFEQDEKAPL----------PHVFRINGWHVAEYV 331
            :::|.::.:|:.::.:.|     :||.:..|...|..|.|          .|...:..|.: ...
Zfish   253 RNLPLSIAISMPIVTIIY-----ILTNVAYYAVLDMSAILASDAVAVTFADHTLGVMSWTI-PIA 311

  Fly   332 VSIGAMFGLCSSMMGAMFPLPRIVFAMSNDGLLFKFLGDISEKYKTPFKGTMITGMLTGILAAVF 396
            |::....||.||::.|    .|:.|..:.:|.|...|..|..:..||....:....:..|...|.
Zfish   312 VALSCYGGLNSSIIAA----SRLFFVGAREGHLPDALSMIHIERFTPVPALLFNCAMALIYLTVE 372

  Fly   397 NLSQLVNMMSIGTLLAYSMVASCVLMLRYEVDDRRESRIVANGRATGLEQDRPCALWRRIFNLNG 461
            ::.||:|..|........:..:..:.||::                  |.|||
Zfish   373 DVFQLINYYSFSYWFFVGLSIAGQIYLRWK------------------EPDRP------------ 407

  Fly   462 QTVPTKQTSRIVTYSVTLFSLWCMVFSQILTKFEEDLANVTSFDGIKLVLGTIPLAVLLLVI--S 524
              .|.|.:   :.|.: :|.| |:||...:..:.:.|   .|..||.:.|..:|:..|.:.:  |
Zfish   408 --RPLKLS---LVYPI-IFCL-CVVFLVAVPLYSDTL---NSLIGIAIALSGVPVYFLGIHLPES 462

  Fly   525 RQPTSGVKL 533
            ::|....||
Zfish   463 KRPPIITKL 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5535	NP_649019.2	2A0303	20..585	CDD:273330	126/529 (24%)
CG5535	NP_649019.2	AA_permease_C	535..585	CDD:290617
slc7a6	XP_005166451.1	2A0308	2..489	CDD:273332	126/529 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593075
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.850