Protein Alignment CG5535 and SLC7A10

DIOPT Version :9

• Sequence 1: NP_649019.2
• Gene: CG5535 / 39990
• FlyBaseID: FBgn0036764
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: XP_011525421.1
• Gene: SLC7A10 / 56301
• HGNCID: 11058
• Length: 660
• Species: Homo sapiens
• Alignment Length: 651
• Identity: 117/651 - (17%)
• Similarity: 216/651 - (33%)
• Gaps: 241/651 - (37%)

  Fly    31 SNESKLAKVLSAFDLTALGIGSTLGVGVYVL-------AGEVSKQYAGPAVVVSFLIAAIASIFA 88
            |....|.|.:.......:.||:.:|.|:::.       :|.|     |.|:.|..|...:.:: .
Human    31 SERVALKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHSGSV-----GLALFVWVLGGGVTAL-G 89

  Fly    89 GLCYAEFGARVPKAGSAYIYSYVTIGEFIAFLIGWNLIL-EYAIGSASVVKGLSTYLDQ----LC 148
            .|||||.|..:||:|..|.|.....|....||:.|:.:| .|....|.:....|.|:.|    .|
Human    90 SLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVISMTFSNYVLQPVFPNC 154

  Fly   149 GNPMSSFLGTHMPLNIEGMGAYPDLFAFVVTILFSLAIAVGAKESTRVNNVFT-------MLNLG 206
            ..|.::                ..:.:....:|.:...:...:.:||:.::||       .|.:|
Human   155 IPPTTA----------------SRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLIIG 203

  Fly   207 VVLFVIIAGLF-KVSSSN----WSIPKSQVPEGYGDGGFMPYGVSGIIKGAAVCFYGFIGFDCIA 266
            |.|..|..|.| ::..||    |..|.            :.:.....::|:    :.|.|::.:.
Human   204 VGLLQIFQGHFEELRPSNAFAFWMTPS------------VGHLALAFLQGS----FAFSGWNFLN 252

  Fly   267 TAGEEAKNPKKSIPFAVIVSLAMIF-------LAYF------------GVSTVLTMML------- 305
            ...||..:.:|::|.|:.:|:.::.       :|||            .|:.|...:|
Human   253 YVTEEMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVVSGPLLGPWLLPR 317

  Fly   306 ----PY-------------------------------FEQDEKAPLPHVFRING----------- 324
                ||                               ..:|:..|: |:.::..
Human   318 PLPRPYTWPLYCAHPDLRGEAAGLLFLGHACLRGSVNLRRDQWLPV-HLLQVTALGRRGHGEGRL 381

  Fly   325 ---------W--------------------HVAEYVVSIGAM---------------FGLC---- 341
                     |                    |..:.:::.|..               .||.
Human   382 GCRCAPVMPWARGRDTCRGRGLPEAGMMIPHGNKCLITTGRQRKQEAGRLDEGENCPVGLLGPEQ 446

  Fly   342 ----SSMMGA--------MFPLP------RIVFAMSNDGLLFKFLGDISEKYKTPFKGTMITGML 388
                .|:.|.        |:|:|      |:.|:.:.:|.|...|..|..::.||....::....
Human   447 EVRGDSLRGTSGPKLRPRMWPVPISVPNARLCFSGAREGHLPSLLAMIHVRHCTPIPALLVCCGA 511

  Fly   389 TGILAAVFNLSQLVNMMSIGTLLAYSMVASCVLMLRYEVDDRRESRIVANGRATGLEQDRPCALW 453
            |.::..|.:...|:|.:|....|.|.:....:|:||:.                     || ||.
Human   512 TAVIMLVGDTYTLINYVSFINYLCYGVTILGLLLLRWR---------------------RP-ALH 554

  Fly   454 RRIFNLNGQTVPTKQTSRIVTYSVTLFSLWCMVFSQILTKFEEDLANVTSFDGIKLVLGTIPLAV 518
            |.|           :.:.::..:..:|..:.:|||.|   .|..:..|    |:.::|..:|:..
Human   555 RPI-----------KVNLLIPVAYLVFWAFLLVFSFI---SEPMVCGV----GVIIILTGVPIFF 601

  Fly   519 L 519
            |
Human   602 L 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5535	NP_649019.2	2A0303	20..585	CDD:273330	117/651 (18%)
		AA_permease_C	535..585	CDD:290617
SLC7A10	XP_011525421.1	2A0308	15..635	CDD:273332	117/651 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157257
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.850