Protein Alignment CG5535 and Slc7a14

DIOPT Version :10

• Sequence 1: NP_649019.2
• Gene: CG5535 / 39990
• FlyBaseID: FBgn0036764
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_001425198.1
• Gene: Slc7a14 / 499587
• RGDID: 1594375
• Length: 771
• Species: Rattus norvegicus
• Alignment Length: 692
• Identity: 267/692 - (38%)
• Similarity: 397/692 - (57%)
• Gaps: 126/692 - (18%)

  Fly     5 AEYYGMPSWSVTNAFRVLTRKKPLEDSNE---------SKLAKVLSAFDLTALGIGSTLGVGVYV 60
            |.:|.|.|       |:| |.||:|...|         :|||:||:..||.:||:||.:|.|:||
  Rat    17 AAWYAMHS-------RIL-RTKPVESMLEGTGATSAHGTKLAQVLTTVDLISLGVGSCVGTGMYV 73

  Fly    61 LAGEVSKQYAGPAVVVSFLIAAIASIFAGLCYAEFGARVPK-AGSAYIYSYVTIGEFIAFLIGWN 124
            ::|.|:|:.|||.|:|||:|||:|||.:|:||||||.|||| .||||.|||||:|||:||.||||
  Rat    74 VSGLVAKEMAGPGVIVSFIIAAVASILSGVCYAEFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWN 138

  Fly   125 LILEYAIGSASVVKGLSTYLDQLCGNPMSSFL----GTHMPLNIEGMG--AYPDLFAFVVTILFS 183
            |||||.||:|:....||:..|.|..:.:|.::    ||   ||..|.|  :||||.|.|:.::.:
  Rat   139 LILEYLIGTAAGASALSSMFDSLANHTISRWMVDTVGT---LNGLGKGEESYPDLLALVIAVIVT 200

  Fly   184 LAIAVGAKESTRVNNVFTMLNLGVVLFVIIAGLFKVSSSNWSIPKSQVPEGYGDGGFMPYGVSGI 248
            :.:|:|.|.|...|||..:|||.|.:|::|||||.|:...|:           :|.|:|:|.||:
  Rat   201 IIVALGVKNSVGFNNVLNVLNLAVWVFIMIAGLFFVNGKYWA-----------EGQFLPHGWSGV 254

  Fly   249 IKGAAVCFYGFIGFDCIATAGEEAKNPKKSIPFAVIVSLAMIFLAYFGVSTVLTMMLPYFEQDEK 313
            ::|||.|||.|||||.|||.|||||||..|||:|:..||.:...||..||.:||:|:||:..|.:
  Rat   255 LQGAATCFYAFIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSMILTLMVPYYAIDTE 319

  Fly   314 APLPHVFRINGWHVAEYVVSIGAMFGLCSSMMGAMFPLPRIVFAMSNDGLLFKFLGDISEKYKTP 378
            :||..:|..:|::.|::||:||::.||..|::|::||:||:::||:.|||||:||..:|...:||
  Rat   320 SPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHVSSYTETP 384

  Fly   379 FKGTMITGMLTGILAAVFNLSQLVNMMSIGTLLAYSMVASCVLMLRYEVDD-------------- 429
            ....:::|.|..:|:.:.:|..|:.||||||||||::|:.|||:|||:.:.
  Rat   385 VVACIVSGFLAALLSLLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQPESDIDGFVKFLSEEHT 449

  Fly   430 RRESRIVAN--------------------------------------GRA--------------- 441
            :::..|:|:                                      |::
  Rat   450 KKKEGILADCEKETCSPVSEGEEFSSPATNTCGAKNLPSLGDNEMLIGKSDKSAYNVNHPNYGTV 514

  Fly   442 ---TGLEQDR--------------PCALWRRI-FNLNGQ-TVPTKQTSRIVTYSVTLFSLWCMVF 487
               ||:|.|.              |.....|| ..|.|: ..||..|...||..|.|..:...:|
  Rat   515 DMTTGIEADESENIYLIKLKKLIGPRYYTMRIRLGLPGKMDRPTAATGHTVTICVLLLFILMFIF 579

  Fly   488 SQILTKFEEDLANVTSFDGIKLVLGTIPLAVLLLVISRQPTSGVKLSFKVPLVPWLPGISILINI 552
            ...:....|.::..:.:..:.:||..:.:.||:.||.:||.:..||.:..|.:|::|..::|:||
  Rat   580 CSFVIFGSEYISGQSWWAILLVVLMLLLITVLVFVILQQPENPKKLPYMAPCLPFVPAFAMLVNI 644

  Fly   553 YLMIKLDILTWIRFSIWIAIGLAIFLAYGIRHSRLR--QREQ 592
            |||:||..:|||||::|..:|:.|:..|||.:|.|.  .|||
  Rat   645 YLMLKLSTITWIRFAVWCFVGMLIYFGYGIWNSTLEISAREQ 686

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5535	NP_649019.2	2A0303	20..585	CDD:273330	258/666 (39%)
Slc7a14	NP_001425198.1	None