Protein Alignment CG5535 and slc7a3a

DIOPT Version :10

• Sequence 1: NP_649019.2
• Gene: CG5535 / 39990
• FlyBaseID: FBgn0036764
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_001007330.2
• Gene: slc7a3a / 492363
• ZFINID: ZDB-GENE-041114-206
• Length: 644
• Species: Danio rerio
• Alignment Length: 642
• Identity: 282/642 - (43%)
• Similarity: 411/642 - (64%)
• Gaps: 63/642 - (9%)

  Fly    21 VLTRKKPLEDS-NESKLAKVLSAFDLTALGIGSTLGVGVYVLAGEVSKQYAGPAVVVSFLIAAIA 84
            :|.|::.|:.| .|::.|:.||..||.|||:|||||.|||||||||:::.||||:|:.||:||::
Zfish    11 ILLRRRALDFSGEETRFARCLSTLDLVALGVGSTLGAGVYVLAGEVAREKAGPAIVLCFLVAALS 75

  Fly    85 SIFAGLCYAEFGARVPKAGSAYIYSYVTIGEFIAFLIGWNLILEYAIGSASVVKGLSTYLDQLCG 149
            |:.||||||||||||||.||||:|||||:||..||:.||||||.|.||:|||.:..|:..|.|..
Zfish    76 SMLAGLCYAEFGARVPKTGSAYLYSYVTVGEIWAFITGWNLILSYVIGTASVARAWSSTFDNLIE 140

  Fly   150 NPMSSFLGTHMPLNIEG--MGAYPDLFAFVVTILFSLAIAVGAKESTRVNNVFTMLNLGVVLFVI 212
            ..:|:|....|.:.:.|  :..||||||.::.:|.:..:|.|..||..||.:||.:||.|:.|:|
Zfish   141 QKISNFFRASMAMKVPGKVLAEYPDLFALILILLLTGLLAFGVSESALVNKIFTGINLIVLGFII 205

  Fly   213 IAGLFKVSSSNWSI------------PKSQVPEGYGDGGFMPYGVSGIIKGAAVCFYGFIGFDCI 265
            |:|..|.:::||::            ...::...:|.|||.|:|:.||:.|||.|||.|:|||||
Zfish   206 ISGFVKGNTANWNLTYEYFINDTNITEPERIESTFGSGGFAPFGLGGILSGAATCFYAFVGFDCI 270

  Fly   266 ATAGEEAKNPKKSIPFAVIVSLAMIFLAYFGVSTVLTMMLPYFEQDEKAPLPHVFRINGWHVAEY 330
            ||..||||||.:|||..::.||.:.|.||||||..||:|:||::.:.::|||..|...||..|.|
Zfish   271 ATTSEEAKNPMRSIPVGIVASLLICFFAYFGVSAALTLMMPYYKLNTQSPLPEAFSYVGWAPARY 335

  Fly   331 VVSIGAMFGLCSSMMGAMFPLPRIVFAMSNDGLLFKFLGDISEKYKTPFKGTMITGMLTGILAAV 395
            :|::|::..|.:|::|:|||:||:::||:.|||||:.|..::::.|||...|:.:|::..::|.:
Zfish   336 IVAVGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFRSLSRMNKRTKTPLLATIASGIVAALMAFL 400

  Fly   396 FNLSQLVNMMSIGTLLAYSMVASCVLMLRYEVDDRRES----RIVA------------NGRATGL 444
            |:|:.||::||||||||||:||.|||:|||:..:...|    ::|.            :|...|:
Zfish   401 FDLAALVDLMSIGTLLAYSLVAVCVLILRYQPGNLSSSSQTEKLVELVGGEKVAVCGDSGDEYGV 465

  Fly   445 EQD---RPCALWRRIFNLNGQTVPTKQTSRIVTYSVT-----LFSLWCMVFSQILTKFEEDLAN- 500
            |.|   |......::..:..:..||:.:..|| |..|     |.::.|:|.:|.|    |.:.|
Zfish   466 ELDDSPRKEKFTAKLLLVPSKDSPTEMSGTIV-YGTTAIISVLITVLCVVLAQRL----ESIINL 525

  Fly   501 ----VTSFDGIKLVLGTIPLAVL-LLVISRQPTSGVKLSFKVPLVPWLPGISILINIYLMIKLDI 560
                ||:.  :.|||    |.|| ::||.|||.|...|:|||||:||||..||.:|||||::||:
Zfish   526 EIVWVTAC--VILVL----LCVLCVIVIFRQPESKEALTFKVPLLPWLPLFSIFVNIYLMMQLDV 584

  Fly   561 LTWIRFSIWIAIGLAIFLAYGIRHSRLRQREQRNNSIAMMRDC---SNSALLGGQEN 614
            .||.||::|:|||.||:..|||.||    .|..|:|:......   .:...|||:|:
Zfish   585 ATWCRFTVWMAIGFAIYFGYGIWHS----TEAMNSSVRKYEPALQNKSPIYLGGEES 637

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5535	NP_649019.2	2A0303	20..585	CDD:273330	273/608 (45%)
slc7a3a	NP_001007330.2	2A0303	4..611	CDD:273330	275/614 (45%)