DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5535 and sbm

DIOPT Version :9

Sequence 1:	NP_649019.2	Gene:	CG5535 / 39990	FlyBaseID:	FBgn0036764	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	NP_727785.1	Gene:	sbm / 32397	FlyBaseID:	FBgn0030574	Length:	541	Species:	Drosophila melanogaster

Alignment Length:	430	Identity:	102/430 - (23%)
Similarity:	170/430 - (39%)	Gaps:	70/430 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 KKPLEDSNESK-----LAKVLSAFDLTALGIGSTLGVGVYVLAGEVSKQYAGPAVVVSFLI---A 81
            :||||.:..::     |.:.|..|...||.:|:.:|.|::|....:..:..  :|.|||:|   .
  Fly    64 RKPLERNGSTQNHVVHLERRLGLFSGVALIVGTMIGSGIFVSPSGLLVRTG--SVGVSFIIWLAC 126

  Fly    82 AIASIFAGLCYAEFGARVPKAGSAYIYSYVTIGEFIAFLIGW--NLIL-------------EYAI 131
            .:.|:...|.|||.|.....:|:.:.|.....|...|||..|  .|:|             :||:
  Fly   127 GVLSLLGALAYAELGTMNTSSGAEWAYFMDAYGPAPAFLFSWVSTLVLKPSQMAIICLSFAQYAV 191

  Fly   132 GSASVVKGLSTYLDQLCGNPMSSFLGTHMPLNIEGMGAYPDLFAFVVTILFSLAIAVGAKESTRV 196
             .|.|.:         |..|             .|:.....|.| :|.|||....:|..  ...|
  Fly   192 -EAFVTE---------CDPP-------------RGVVKMVALVA-IVMILFVNCYSVNL--GMAV 230

  Fly   197 NNVFTMLNLGVVLFVIIAGLFKVSSSNWSIPKSQVPEGYGDGGFMPYGVSGIIKGAAVCFY---- 257
            .||||...|..|:.||..|.:|:...|    ...:...:  .|.|| .|..|    |..||
  Fly   231 QNVFTAAKLVAVVVVICGGAWKLMQGN----TQHLSNAF--NGPMP-NVGAI----ATAFYTGLW 284

  Fly   258 GFIGFDCIATAGEEAKNPKKSIPFAVIVSLAMIFLAY--FGVSTVLTMMLPYFEQDEKAPLPHVF 320
            .:.|::.:....||.|||.|::|.::|:.:.::.|.|  ..:|.:..|......:.|...:....
  Fly   285 AYDGWNNLNYVTEEIKNPSKNLPRSIIIGIPLVTLCYALINISYLAAMSPQEMIESEAVAVTFGN 349

  Fly   321 RINGWHVAEYVVSIGAMFGLCSSMMGAMFPLPRIVFAMSNDGLLFKFLGDISEKYKTPFKGTMIT 385
            ||.|  ...:::.:........|..|.:|...|:.||.|.:|.|...|..:..:..||..|.:..
  Fly   350 RILG--ALAWLMPLSVTISTFGSANGTLFAAGRLCFAASREGHLLDILSYVHVRRLTPAPGLIFH 412

  Fly   386 GMLTGILAAVFNLSQLVNMMSIGTLLAYSMVASCVLMLRY 425
            .::...:.....:..|::..|....:.|......::::||
  Fly   413 SLIASAMVLHGTIDSLIDFFSFTAWIFYGGAMLALIVMRY 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5535	NP_649019.2	2A0303	20..585	CDD:273330	102/430 (24%)
CG5535	NP_649019.2	AA_permease_C	535..585	CDD:290617
sbm	NP_727785.1	2A0308	53..532	CDD:273332	102/430 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466568
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840