DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5535 and Slc7a13

DIOPT Version :9

Sequence 1:	NP_649019.2	Gene:	CG5535 / 39990	FlyBaseID:	FBgn0036764	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	NP_001012100.1	Gene:	Slc7a13 / 313089	RGDID:	1311633	Length:	479	Species:	Rattus norvegicus

Alignment Length:	503	Identity:	112/503 - (22%)
Similarity:	198/503 - (39%)	Gaps:	111/503 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 LAKVLSAFDLTALGIGSTLGVGVYVLAGEVSKQYAGPAVVVS---FLIAAIASIFAGLCYAEFGA 97
            |.:.|..|..|...|.:.:|.|::|....| .||:...|.||   ::..|:.|:.:.||.||.|.
  Rat    11 LKRQLGYFWGTNFLIINIIGAGIFVSPKGV-LQYSSMNVGVSLCVWVFCAVLSMTSTLCAAEIGI 74

  Fly    98 RVPKAGSAYIYSYVTIGEFIAFLIGWN--------------LILEYAIGSASVVKGLSTYLDQLC 148
            ..|...:.|.:.....|.|:|||..|.              |:.||         |:..:... |
  Rat    75 TFPYTVAHYYFLKRCFGPFVAFLRLWTSLFTGPGVLASQALLLAEY---------GIQPFYPS-C 129

  Fly   149 GNPMSSFLGTHMPLNIEGMGAYPD-----LFAFVVTILFSLAIAVGAKESTRVNNVFTMLNLGVV 208
            ..|                 |.|.     ...::|.||.|.    |.||.:.:..|..:|.:|::
  Rat   130 SAP-----------------AVPKKCLALAMLWIVGILNSR----GVKELSWLQTVSMVLKMGIL 173

  Fly   209 LFVIIAGLF-KVSSSNWSIPK------SQVPEGYGDGGFMPYGVSGIIKGAAVCFYGFIGFDCIA 266
            .|:.::||| .|:....::.:      ::.||           ||.:|:.....::.|.|.....
  Rat   174 SFISLSGLFLLVTGRKENVRRLQNAFDAEFPE-----------VSRLIEAIFQGYFAFSGGGSFT 227

  Fly   267 TAGEEAKNPKKSIPFAVIVSLAMIFLAYFGVS-TVLTMMLP--YFEQDEKA------PLPHVFRI 322
            ....|.|.|.|:||..:..:|.::.:.|...: :.||::.|  ....|..|      .:|.:
  Rat   228 YVAGELKEPSKTIPRCIFTALPLVTVVYLLANLSYLTVLSPQELLSSDAVALTWTDRVIPQL--- 289

  Fly   323 NGWHVAEYVVSIGAMFGLCSSMMGAMFPLPRIVFAMSNDGLLFKFLGDISEKYKTPFKGTMITGM 387
             .|.| .:.:|.    .|.|:::.::|...|..:..|.:|.| ..|......:.:||...::...
  Rat   290 -TWSV-PFAISA----SLFSNLVTSVFETSRTSYIASRNGQL-PLLCSTLNVHSSPFIAVLLDVS 347

  Fly   388 LTGILAAVFNLSQLVN----MMSIGTLLAYSMVASCVLMLRY-EVDDRRESRIVANGRATGLEQD 447
            :..|...:.||.:|:|    :.||.|:|  |::.  :|.||| |.:..|..::.:
  Rat   348 MGSIAIVLTNLIELINYLFFVFSIWTVL--SVIG--ILKLRYQEPNLHRPYKVFS---------- 398

  Fly   448 RPCALWRRIFNLNGQTVPTKQTSRIVTYSVTLFSLWCMVFSQILTKFE 495
             |........:|:...:|..::.::....|.||.|..::|...|..|:
  Rat   399 -PFLFITAAISLSMVLIPLIKSPKMQYIYVFLFFLGGLLFYVPLIHFK 445

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5535	NP_649019.2	2A0303	20..585	CDD:273330	112/503 (22%)
CG5535	NP_649019.2	AA_permease_C	535..585	CDD:290617
Slc7a13	NP_001012100.1	PotE	11..454	CDD:223605	112/503 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351260
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930