DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5535 and Slc7a15

DIOPT Version :9

Sequence 1:	NP_649019.2	Gene:	CG5535 / 39990	FlyBaseID:	FBgn0036764	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	NP_001100184.1	Gene:	Slc7a15 / 298873	RGDID:	1560726	Length:	488	Species:	Rattus norvegicus

Alignment Length:	396	Identity:	93/396 - (23%)
Similarity:	167/396 - (42%)	Gaps:	41/396 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 SAFDLTALGIGSTLGVGVYVLAGEVSKQYAGP-AVVVSFLIAAIASIFAGLCYAEFGARVPKAGS 104
            ||..:||   |..:|.|:::....|......| |.::.:....:.::...|||||.|:.||::|.
  Rat    35 SAVSMTA---GCMIGSGIFMSPQGVLVYIGSPGASLIIWATCGLLALLGALCYAELGSLVPESGG 96

  Fly   105 AYIYSYVTIGEFIAFLIGWNLILEYAIGSASVVKGLSTYLDQLCGNPMSSFLGTHMPLNIEGMGA 169
            .|.|.....|...|||:.:.::|   :|..:.:..:|.           ||....:.....|..:
  Rat    97 EYAYILRAFGSLPAFLVIYIIVL---VGRPAAITAVSL-----------SFAEYALAPFYPGCSS 147

  Fly   170 YPDLFAFVVT---ILFSLAIAV-GAKESTRVNNVFTMLNLGVVLFVIIAGLFKVSSSNWSIPKSQ 230
            .|.:...:|.   ||..|.|.. .::.||.:.||.|...|..:|.:::.|  .|..:...||...
  Rat   148 VPQVIVKIVACSCILVLLLINFWSSRMSTVLMNVCTAAKLFSLLVIVVGG--AVGLAQGRIPTES 210

  Fly   231 VPEGYGDGGFMPYGVSGIIKGAAVCFY----GFIGFDCIATAGEEAKNPKKSIPFAVIVSLAMIF 291
            :.       |..:..:.......:.||    .|.|:..|.|..||.||||:::.:||::::.::.
  Rat   211 LL-------FAFHNTTQQAGRIGMAFYQGLWSFDGWSNINTVIEEIKNPKQNLVWAVVIAIPLVT 268

  Fly   292 LAYFGVS-TVLTMMLP--YFEQDEKAPLPHVFRINGWHVAEYVVSIGAMFGLCSSMMGAMFPLPR 353
            :.|..|: :.|.:|.|  ....|..|.......:..|   .::|.:........::.|..|...|
  Rat   269 ILYVLVNISYLLVMSPSEILTSDAIAVTWGNQVLGSW---AWLVPLAVALSTFGAVNGGFFSGSR 330

  Fly   354 IVFAMSNDGLLFKFLGDISEKYKTPFKGTMITGMLTGILAAVFNLSQLVNMMSIGTLLAYSMVAS 418
            :.:|.:.:|.:.:.:..|.....||....:.|..:..:|....|.|..||::|..:.|.|....:
  Rat   331 VCYAAAREGHMPQLMSMIHVHRLTPAPALIFTTAVALLLVIPGNFSTFVNLLSFLSWLTYGTTFA 395

  Fly   419 CVLMLR 424
            |:|.||
  Rat   396 CLLYLR 401

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5535	NP_649019.2	2A0303	20..585	CDD:273330	93/396 (23%)
CG5535	NP_649019.2	AA_permease_C	535..585	CDD:290617
Slc7a15	NP_001100184.1	2A0308	4..481	CDD:273332	93/396 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351220
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.850