Protein Alignment CG5535 and Slc7a11

DIOPT Version :9

• Sequence 1: NP_649019.2
• Gene: CG5535 / 39990
• FlyBaseID: FBgn0036764
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_036120.1
• Gene: Slc7a11 / 26570
• MGIID: 1347355
• Length: 502
• Species: Mus musculus
• Alignment Length: 542
• Identity: 115/542 - (21%)
• Similarity: 212/542 - (39%)
• Gaps: 102/542 - (18%)

  Fly    36 LAKVLSAFDLTALGIGSTLGVGVYVLAGEVSKQYAGPAVVVSFLIA-AIASIFAGLCYAEFGARV 99
            |.|.::.....::.||:.:|.|:::....:.:......:.:.|..| .:.|:|..|.|||.|..:
Mouse    40 LKKKITLLRGVSIIIGTVIGSGIFISPKGILQNTGSVGMSLVFWSACGVLSLFGALSYAELGTSI 104

  Fly   100 PKAGSAYIYSYVTIGEFIAFLIGWNLILEYAIGSASVVK-GLSTYLDQLCGNPMSSFLGTHMP-L 162
            .|:|..|.|.....|..:||:..|..:|....|:.:|:. ....|:.:    |.  |:...:| |
Mouse   105 KKSGGHYTYILEVFGPLLAFVRVWVELLVIRPGATAVISLAFGRYILE----PF--FIQCEIPEL 163

  Fly   163 NIEGMGAYPDLFAFVVTILFSLAIAVGAKESTRVNNVFTMLNLGVVLFVIIAGL----------F 217
            .|:.:.|   :...||.:|.|.:::    .|.|:....|...|..:|.:|:.|:          |
Mouse   164 AIKLVTA---VGITVVMVLNSTSVS----WSARIQIFLTFCKLTAILIIIVPGVIQLIKGQTHHF 221

  Fly   218 KVSSSNWSIPKSQVPEGYGDGGFMPYGVSGIIKGAAVCFYGFIGFDCIATAGEEAKNPKKSIPFA 282
            |.:.|........:|..:      .||:           |.:.|:..:....||..||:|:||.|
Mouse   222 KDAFSGRDTSLMGLPLAF------YYGM-----------YAYAGWFYLNFITEEVDNPEKTIPLA 269

  Fly   283 VIVSLAMIFLAYF--GVSTVLTMMLPYFEQDEKAPLPHVFRING-WHVAEYVVSIGAMFGLCSSM 344
            :.:|:|:|.:.|.  .|:...|:......|.....:....|:.| :.:|..:....:.||   ||
Mouse   270 ICISMAIITVGYVLTNVAYFTTISAEELLQSSAVAVTFSERLLGKFSLAVPIFVALSCFG---SM 331

  Fly   345 MGAMFPLPRIVFAMSNDGLLFKFLGDISEKYKTPFKGTMITGMLTGILAAVFNLSQLVNMMSIGT 409
            .|.:|.:.|:.:..|.:|.|.:.|..|.....||....::...||.::....:|..|:|.:|...
Mouse   332 NGGVFAVSRLFYVASREGHLPEILSMIHVHKHTPLPAVIVLHPLTMVMLFSGDLYSLLNFLSFAR 396

  Fly   410 LLAYSMVASCVLMLRYEVDDRRESRIVANGRATGLEQDRPCALWRRIFNLNGQTVPTKQTSRIVT 474
            .|...:..:.::.|||:..|                ..||                    .::..
Mouse   397 WLFMGLAVAGLIYLRYKRPD----------------MHRP--------------------FKVPL 425

  Fly   475 YSVTLFSLWCMVFSQILTKFEEDLANVTSFDGIKLVLGTIPLAVLLLVISRQPTSGVKLSFKVPL 539
            :...|||..|: |..:|:.:.:..:...   |..:.|..:|...|.:|..::|
Mouse   426 FIPALFSFTCL-FMVVLSLYSDPFSTGV---GFLITLTGVPAYYLFIVWDKKP------------ 474

  Fly   540 VPWLPGISILINIYLMIKLDIL 561
             .|...:|..|...|.|.|:::
Mouse   475 -KWFRRLSDRITRTLQIILEVV 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5535	NP_649019.2	2A0303	20..585	CDD:273330	115/542 (21%)
		AA_permease_C	535..585	CDD:290617	6/27 (22%)
Slc7a11	NP_036120.1	2A0308	1..498	CDD:273332	115/542 (21%)
		SLC5-6-like_sbd	42..>291	CDD:294310	64/278 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847645
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.850