Protein Alignment CG5535 and Slc7a1

DIOPT Version :10

• Sequence 1: NP_649019.2
• Gene: CG5535 / 39990
• FlyBaseID: FBgn0036764
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_001386911.1
• Gene: Slc7a1 / 25648
• RGDID: 3716
• Length: 624
• Species: Rattus norvegicus
• Alignment Length: 634
• Identity: 281/634 - (44%)
• Similarity: 405/634 - (63%)
• Gaps: 63/634 - (9%)

  Fly    22 LTRKKPLEDS-NESKLAKVLSAFDLTALGIGSTLGVGVYVLAGEVSKQYAGPAVVVSFLIAAIAS 85
            :.|:|.::.| .||:|::.|:.:||.|||:|||||.|||||||.|:::.||||:|:||||||:||
  Rat    13 MLRRKVVDCSREESRLSRCLNTYDLVALGVGSTLGAGVYVLAGAVARENAGPAIVISFLIAALAS 77

  Fly    86 IFAGLCYAEFGARVPKAGSAYIYSYVTIGEFIAFLIGWNLILEYAIGSASVVKGLSTYLDQLCGN 150
            :.|||||.||||||||.||||:|||||:||..||:.||||||.|.||::||.:..|...|:|.|.
  Rat    78 VLAGLCYGEFGARVPKTGSAYLYSYVTVGELWAFITGWNLILSYIIGTSSVARAWSATFDELIGK 142

  Fly   151 PMSSFLGTHMPLNIEGMGAY-PDLFAFVVTILFSLAIAVGAKESTRVNNVFTMLNLGVVLFVIIA 214
            |:..|...||.||..|:.|. ||:||.::.|:.:..:.:|.|||..||.:||.:|:.|:.|::::
  Rat   143 PIGEFSRQHMALNAPGVLAQTPDIFAVIIIIILTGLLTLGVKESAMVNKIFTCINVLVLCFIMVS 207

  Fly   215 GLFKVSSSNWSIPKSQ---------VPEGYGDGGFMPYGVSGIIKGAAVCFYGFIGFDCIATAGE 270
            |..|.|..||.:.:::         ....||:|||||:|.||::.|||.|||.|:|||||||.||
  Rat   208 GFVKGSIENWQLTENKSSPLCGNNDTNVKYGEGGFMPFGFSGVLSGAATCFYAFVGFDCIATTGE 272

  Fly   271 EAKNPKKSIPFAVIVSLAMIFLAYFGVSTVLTMMLPYFEQDEKAPLPHVFRINGWHVAEYVVSIG 335
            |.|||:|:||..::.||.:.|:||||||..||:|:|||..|..:|||..|:..||..|:|.|::|
  Rat   273 EVKNPQKAIPVGIVASLLICFIAYFGVSAALTLMMPYFCLDTDSPLPGAFKYRGWEEAKYAVAVG 337

  Fly   336 AMFGLCSSMMGAMFPLPRIVFAMSNDGLLFKFLGDISEKYKTPFKGTMITGMLTGILAAVFNLSQ 400
            ::..|.:|::|:|||:||:::||:.||||||||..|:::.|||...|:.:|.:..::|.:|.|..
  Rat   338 SLCALSTSLLGSMFPMPRVIYAMAEDGLLFKFLAKINDRTKTPIIATVTSGAIAAVMAFLFELKD 402

  Fly   401 LVNMMSIGTLLAYSMVASCVLMLRY----------------EVDDRRESRIV-ANGRATGLEQDR 448
            ||::||||||||||:||:|||:|||                |:|...::.:| |:...||.   .
  Rat   403 LVDLMSIGTLLAYSLVAACVLVLRYQPEQPNLVYQMARTTDELDQVDQNEMVSASESQTGF---L 464

  Fly   449 PCALWRRIFNLNGQTV-------PTKQTSRIVTYSVTLFSLWCMVFSQILTKFEEDLANVTSFDG 506
            |.|   ..|:|  :|:       |:|.:..||..|..|.::..:....:.....|.||..|.: .
  Rat   465 PAA---EKFSL--KTILSPKNMEPSKFSGLIVNISAGLLAVLIITVCIVAVLGREALAEGTLW-A 523

  Fly   507 IKLVLGTIPLAVLLL-VISRQPTSGVKLSFKVPLVPWLPGISILINIYLMIKLDILTWIRFSIWI 570
            :.::.|::.|.:|:. :|.|||.|..|||||||.||.||.:||.:|||||::||..||:||::|:
  Rat   524 VFVMTGSVLLCMLVTGIIWRQPESKTKLSFKVPFVPVLPVLSIFVNIYLMMQLDQGTWVRFAVWM 588

  Fly   571 AIGLAIFLAYGIRHSRLRQREQRNNSIAMMRDCSNSALLGGQENSKYSN 619
            .||.||:..||:.||                  ..::|..||..:..||
  Rat   589 LIGFAIYFGYGVWHS------------------EEASLAAGQAKTPDSN 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5535	NP_649019.2	2A0303	20..585	CDD:273330	274/598 (46%)
Slc7a1	NP_001386911.1	2A0303	4..605	CDD:273330	276/618 (45%)