DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5535 and isp5

DIOPT Version :9

Sequence 1:	NP_649019.2	Gene:	CG5535 / 39990	FlyBaseID:	FBgn0036764	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	NP_595000.1	Gene:	isp5 / 2543028	PomBaseID:	SPAC1039.09	Length:	580	Species:	Schizosaccharomyces pombe

Alignment Length:	431	Identity:	92/431 - (21%)
Similarity:	162/431 - (37%)	Gaps:	98/431 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 PLEDSNESKLAKVLSAFDLTALGIGSTLGVGVYVLAGEVSKQYAGPAVVVSFLIAAIASIFAGLC 91
            |.||....||.:.|:|..:..:|||..:|.||:|.:....::....:|::.:.:.....:.....
pombe    70 PPEDGKPQKLKRTLTARHIQMIGIGGAIGTGVWVGSKNTLREGGAASVLICYSLVGSMVLMTVYS 134

  Fly    92 YAEFGARVPKAGSAYIYSYVTIGEFIAFLIGWNLILEY------AIGSASVVKGLSTYLDQLCGN 150
            ..|.....|..||.:.|....|.....|.:|||.:..:      .:.:||:.  |..:::...|.
pombe   135 LGELAVAFPINGSFHTYGTRFIHPSWGFTLGWNYLASFLATYPLELITASIC--LQFWININSGI 197

  Fly   151 PMSSFLGTHMPLNIEGMGAYPDLFAFVVTILFSLAIAVGAKESTRVNNVFTMLNLGVVLFVIIAG 215
            .::.|:.....:|:.|:..|.::..||.::                 .|..|:...:...||..|
pombe   198 WITVFIALLCFVNMFGVRGYGEVEFFVSSL-----------------KVMAMVGFIICGIVIDCG 245

  Fly   216 LFKVSSSNW----SIPKSQVPEGYGDGGFMPYGVSGIIKGAAVCFYGFIGFDCIATAGEEAKNPK 276
            ..:.....:    ...|:....|:       :|...:...||   :.:.|.:.|..|..|.|||.
pombe   246 GVRTDHRGYIGATIFRKNAFIHGF-------HGFCSVFSTAA---FSYAGTEYIGIAASETKNPA 300

  Fly   277 KSIPFAV-----IVSLAMIFLAYFGVSTVLTMMLPYFEQDEK-------APLPHVF-----RING 324
            |:.|.||     .|||..| ||.|.||.:::      .:||:       |..|.:.     :|.|
pombe   301 KAFPKAVKQVFIRVSLFYI-LALFVVSLLIS------GRDERLTTLSATAASPFILALMDAKIRG 358

  Fly   325 W-HVAEYVVSIGAMFGLCSSMMGAMFPLPRIVFAMSNDG----------------------LLFK 366
            . ||...|:.|..:    ::..|..:...|.:.:|:..|                      |.|.
pombe   359 LPHVLNAVILISVL----TAANGITYTGSRTLHSMAEQGHAPKWFKYVDREGRPLLAMAFVLCFG 419

  Fly   367 FLGDISEKYKTPFKGTMITGMLTGILAAVFNLSQLVNMMSI 407
            .||.|.|..::   .|:...:|     ::.||:.|...:||
pombe   420 ALGYICESAQS---DTVFDWLL-----SISNLATLFVWLSI 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5535	NP_649019.2	2A0303	20..585	CDD:273330	92/431 (21%)
CG5535	NP_649019.2	AA_permease_C	535..585	CDD:290617
isp5	NP_595000.1	LysP	37..579	CDD:223903	92/431 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	75	1.000	Inparanoid score	I1891
OMA	1	1.010	-	-		QHG53617
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X81
TreeFam	0	0.000	Not matched by this tool.
	4	3.960