DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5535 and SPBPB2B2.01

DIOPT Version :9

Sequence 1:	NP_649019.2	Gene:	CG5535 / 39990	FlyBaseID:	FBgn0036764	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	NP_596849.1	Gene:	SPBPB2B2.01 / 2541403	PomBaseID:	SPBPB2B2.01	Length:	585	Species:	Schizosaccharomyces pombe

Alignment Length:	520	Identity:	105/520 - (20%)
Similarity:	169/520 - (32%)	Gaps:	176/520 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 EEFAEYYG----MPSWSVTNAFRVLTR----KKPLEDSNESKLAKVLSAFDLTALGIGSTLGVGV 58
            ||...|.|    :|: ...|.||....    :|..:||....|.:.|.:..:..:|||..:|.||
pombe    38 EEVISYVGEVETVPA-KEENVFRRFINGFKIEKNQQDSAGQGLKRRLKSRHIQMIGIGGAIGTGV 101

  Fly    59 YVLAGEVSKQYAGPA--VVVSFLIAAIASIFAGLCYAEFGARVPKAGSAYIYSYVTIGEFIAFLI 121
            :|  |.....|.|.|  |::.:.|.............|.....|..||...::...|.|...|.:
pombe   102 WV--GSSKSLYRGGAASVLIDYCIVGTMVFCTVYALGELAVAFPTRGSFVTHATRFIDESWGFAL 164

  Fly   122 GWNLILEYAIGSASVVKGLSTYLDQLCGNPMSSFLGTHMPLNIEGMGAYPDLFAFVVTILFSLAI 186
            .||.:                                               |:|:|||  .|.:
pombe   165 SWNYV-----------------------------------------------FSFIVTI--PLEL 180

  Fly   187 AVGAKESTRVNNVFTMLNLGVVLFVIIAGLFKVSSSNWSIPKSQVPEGYGD-------------G 238
            ..|    |.:...:|.||.|:.:.|.|..||.::...        .:|||:             .
pombe   181 TTG----TMMIKYWTNLNSGIWVTVFIVFLFFINIFG--------VKGYGEMEFIMSTIKVVAMC 233

  Fly   239 GFMPYGV----SGI---------------------IKGAAVCF----YGFIGFDCIATAGEEAKN 274
            ||:..|:    .|:                     .||....|    :.|.|.:.:..|..|.:|
pombe   234 GFIILGIIIDCGGVPTDHRGYMGTHIFRENAFRHKFKGFCAVFTSAAFSFSGTEYVGVAAAETEN 298

  Fly   275 PKKSIPFAV-----------IVSLAMIFLAYFGVSTVLTMMLPYFEQDEKAPLPHVFRINGWHVA 328
            |.|:.|.||           |:||.::.|...|....||   .|...|..   |.|..|...::.
pombe   299 PAKAFPVAVRQTLFRIAIFYILSLFIVSLLISGADPRLT---SYHGVDAS---PFVLAIKDANIK 357

  Fly   329 EYVVSIGA--MFGLCSSMMGAMFPLPRIVFAMSNDG----------------------LLFKFLG 369
            .....:.|  :..:.||....::...|.:.::..:|                      .||.|||
pombe   358 ALPSILNAIILISVISSANAQLYAGSRAIHSLGCNGFAPKCFTLVDREGRPLVALLILFLFMFLG 422

  Fly   370 DISEKYKTPFKGTMITGMLTGILAAVFNLSQLVNMMSIGTLLAYSMVASCVLMLRYEVDDRRESR 434
            .:.|               ||....||:  .::::..:|||..:..:  |:..:||....:.::|
pombe   423 YLVE---------------TGQYDTVFD--WMLSISGLGTLFCWGSI--CLAHIRYRAAMKHQNR 468

Fly 435 434
pombe 469 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5535	NP_649019.2	2A0303	20..585	CDD:273330	98/498 (20%)
CG5535	NP_649019.2	AA_permease_C	535..585	CDD:290617
SPBPB2B2.01	NP_596849.1	LysP	36..584	CDD:223903	105/520 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	75	1.000	Inparanoid score	I1891
OMA	1	1.010	-	-		QHG53617
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X81
TreeFam	0	0.000	Not matched by this tool.
	4	3.960