DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5535 and SPBC1652.02

DIOPT Version :9

Sequence 1:	NP_649019.2	Gene:	CG5535 / 39990	FlyBaseID:	FBgn0036764	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	NP_596769.2	Gene:	SPBC1652.02 / 2540163	PomBaseID:	SPBC1652.02	Length:	594	Species:	Schizosaccharomyces pombe

Alignment Length:	386	Identity:	88/386 - (22%)
Similarity:	151/386 - (39%)	Gaps:	62/386 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 SVTNAFRVLTRKKPLEDSNESKLAKVLSAFD------LTALGIGSTLGVGVYVLAGEVSKQYAGP 72
            ||..:|....|...|...||  .|:|.::.|      |..:.|||.:|.|::|..|: |.:.|||
pombe    39 SVGTSFLDFFRSYKLRPDNE--FAEVHNSEDFLKPRHLQMIAIGSCIGTGLFVSTGK-SLKNAGP 100

  Fly    73 -AVVVSFLIAAIASIFAGLCYAEFGARVPKAGSAYIYSYVTIGEFIAFLIGWNLILEYAIGSASV 136
             :::::|:|.:...:...|...|....:|...|..:|:...:...|.|...|.....:.....|.
pombe   101 GSLMINFIILSAMILALILSLGEMCCFLPNQSSITMYTGRLLNNNIGFAQSWLYFWIWLTVLPSE 165

  Fly   137 VKGLSTYLDQLCGNPMSSFLGTHMPLNIEGMGAYPDLFAFVVTILFSLAIAVGAKESTRVNNVFT 201
            :......:|          ..|...||       |.::..:......|..|.||:.......|.:
pombe   166 ISAACEVVD----------FWTTQHLN-------PAIWVTIFLAYVVLVNAFGARSYGECEFVSS 213

  Fly   202 MLNLG-VVLFVIIAGLFKVSSSNWSIPKSQVPEGYGDGGFM-------PYGVSGIIKGAAVCF-- 256
            .|.:. |::|..:|.:....::    ||         ||::       |.......||....|
pombe   214 FLKVVIVIIFFFVAIIINCGAA----PK---------GGYIGAHYWHHPGSFRNGFKGFCSVFIS 265

  Fly   257 --YGFIGFDCIATAGEEAKNPKKSIPFAVIVSLAMIF--LAYFGVSTV--LTMMLPYFEQDEKAP 315
              |...|.:.|.||.....||:::||.||    ..:|  :.:|.:.|:  :|:::||...|....
pombe   266 SAYSLSGTENIGTAAGNTSNPQRAIPSAV----KKVFYRMGFFYIITIFLITLVVPYDNPDLGNV 326

  Fly   316 LPHVFRI--NGWHVAEYVVSIGAMFGLCSSMMGAMFPLPRIVFAMSNDGLLFKFLGDISEK 374
            .|.:..|  .|.||..::.:...:..:.|....|:|...|...|:...|...:|||.:.:|
pombe   327 SPFIIAIKNGGIHVLPHITNAVILVSVLSVGNAAVFAASRNAMALVKQGWAPRFLGRVDQK 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5535	NP_649019.2	2A0303	20..585	CDD:273330	85/380 (22%)
CG5535	NP_649019.2	AA_permease_C	535..585	CDD:290617
SPBC1652.02	NP_596769.2	LysP	31..542	CDD:223903	88/386 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X81
TreeFam	0	0.000	Not matched by this tool.
	3	2.910