DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5535 and SPCC965.11c

DIOPT Version :9

Sequence 1:	NP_649019.2	Gene:	CG5535 / 39990	FlyBaseID:	FBgn0036764	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	NP_588521.1	Gene:	SPCC965.11c / 2539173	PomBaseID:	SPCC965.11c	Length:	537	Species:	Schizosaccharomyces pombe

Alignment Length:	587	Identity:	106/587 - (18%)
Similarity:	200/587 - (34%)	Gaps:	171/587 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 DSNESKLAKVLSAFDLTALGIGSTLGVGVYVLAGEVSKQYAGP-AVVVSFLIAAIASIFAGLCYA 93
            ::|.:.:.:.|....::.:.:...:|.||::..|. :....|| .::|.|.|.:|......|...
pombe    34 ENNSNGIKRGLKTRHVSMMALAGIIGPGVFIGMGS-ALHIGGPVGLIVGFAIVSIVVFGVMLSIG 97

  Fly    94 EFGARVPKAGSAYIYSYVT-----IGEFIAFLIGWNLILEYAIGSASVVKGLSTYLDQLCGNPMS 153
            ||       .|.:.:::.|     :.......||||.::.:....|:....|::.|
pombe    98 EF-------NSLFDFNFNTHAARWVDPAFGAAIGWNYVIVWLTNIAAEYTSLTSIL--------- 146

  Fly   154 SFLGTHMPLNIEGMGAYPDLFAFVVTILFSLAIAVGAKESTRVNNVFTMLNLGVVLFVII--AGL 216
            .:.|.|:|    ..|.:...:.| .|....|.::|..:....:..:..:...|..:|.||  ||
pombe   147 QYWGPHVP----SYGFFLIFWGF-FTCYQMLGVSVFGESEYILAFIKLLFITGFYIFAIIYAAG- 205

  Fly   217 FKVSSSNWSIPKSQVPEGYGDGGFMP--YGVSGIIKGAAVCFYGFIGFDCIATAGEEAKNPKKSI 279
                    .||..:.|..:.:   ||  :|..||:.........|.|.:.::....|:|||||:|
pombe   206 --------GIPHHKPPNLFKE---MPLAHGFGGIVSAFVYAGVFFSGVESVSMTAAESKNPKKAI 259

  Fly   280 PFAVIVSLAMIFLAYFGVSTVLTMMLPYFE-------QDEKAPLPHVFRINGW-HVAEYVVSIGA 336
            |.||..:...|...|||:|....:.:.:.:       :..|:|:.......|| |..::|.:: .
pombe   260 PLAVRQTFWRILYVYFGISISYGITVAWNDPNLSSGSKTLKSPMTIAIMNAGWNHAGDFVNAV-I 323

  Fly   337 MFGLCSSMMGAMFPLPRIVFAMSNDGLLFKFLGDISEKYKTPFKGTMITGMLTGILAAVFNLSQL 401
            :....||:...::...|.::.::.||:..|....: :|...|:.......:        |....:
pombe   324 LITCLSSINSGIYIGSRSLYNLAKDGMAPKIFKRV-DKRGVPWVAVHSVHL--------FGFLSI 379

  Fly   402 VNMMSIGTLLAYSMVASCVLMLRYEVDDRRESRIVANGRATGLEQDRPCALWRRIFNLNGQTVPT 466
            :| .|.|.:.||..                                        |.||.|
pombe   380 MN-YSTGAVKAYGY----------------------------------------IINLAG----- 398

  Fly   467 KQTSRIVTYSVTLFSLWCMVFSQILTKFEEDLANVTSFDGIKLVLGTIPLAVLLLVISRQPTSGV 531
                      |:.|.:|..:.                |...:...|.:          :|..:..
pombe   399 ----------VSAFIVWTAII----------------FVHFRFRRGWV----------KQGYALS 427

  Fly   532 KLSFKVPLVPWLPGISILINI----------------------YLMIKLDILTWIRFSI-----W 569
            .|.||.||.|:...|..:|.|                      |:::.|..:.|:.:..     |
pombe   428 DLPFKSPLYPFPQLIGFVIGIILTLVQGWTVFKPFAAGDFVDAYILLPLFFVIWLSYKFIKKTKW 492

  Fly   570 IA 571
            ::
pombe   493 VS 494

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5535	NP_649019.2	2A0303	20..585	CDD:273330	106/587 (18%)
CG5535	NP_649019.2	AA_permease_C	535..585	CDD:290617	12/64 (19%)
SPCC965.11c	NP_588521.1	LysP	1..537	CDD:223903	106/587 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2006
SonicParanoid	1	1.000	-	-		X81
TreeFam	0	0.000	Not matched by this tool.
	4	3.940