DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5535 and SPCC584.13

DIOPT Version :9

Sequence 1:	NP_649019.2	Gene:	CG5535 / 39990	FlyBaseID:	FBgn0036764	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	NP_588218.1	Gene:	SPCC584.13 / 2539095	PomBaseID:	SPCC584.13	Length:	544	Species:	Schizosaccharomyces pombe

Alignment Length:	458	Identity:	110/458 - (24%)
Similarity:	178/458 - (38%)	Gaps:	136/458 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 SNESKLA---------KVLSAF-----DLTALGIGSTLGVGVYVLAGEVSKQYAG-PAVVVSFLI 80
            |:|:.||         :..||:     ..:.||:..:....:|...|     ||| ||:|..:||
pombe    23 SDEADLAALGYKQEFKREFSAWTSFCVSFSVLGLLPSFASTMYYTTG-----YAGTPAMVWGWLI 82

  Fly    81 A-----AIASIFAGLCYAEFGARVPKAGSAYIYSYVTI----GEFIAFLIGWNLILEYAIGSASV 136
            |     .:|:..|.||     :.:|.:|..|..:.|..    |.|.|:|.||
pombe    83 AMVFVQCVANGMAELC-----SSMPTSGGLYYAAAVLAPKGWGPFAAWLTGW------------- 129

  Fly   137 VKGLSTYLDQLCGNP--MSSFLG-------THMPLNIEGMGAYPDLFAFVVTILFSLAIAVGAKE 192
                |.||.|:.|.|  ..||.|       .|.| |.|....  .:|...|..:    ||.|...
pombe   130 ----SNYLVQVTGPPSVAYSFAGMILTLVQLHNP-NFETQNY--QIFLLAVAAM----IAQGFIS 183

  Fly   193 S--TRVNNVF----TMLN---LGVVLFVIIAGLFKVSSSNWSIPKSQVPEGY------------- 235
            |  |:|..||    |:||   |.:|:..::|           :..::.|.|:
pombe   184 SMPTKVLAVFNTWGTVLNMLFLAIVMITVLA-----------VAGTKTPRGFNSNHKVWNEFDNQ 237

  Fly   236 ---GDGGFMPYGVSGIIKGAAVCFYGFIGFDCIATAGEEAKNPKKSIPFAVIVSLAMIFLAYFG- 296
               .:|..|....:|:|       :...|:|......||..|...:.|.|::::.|      ||
pombe   238 TDWSNGMAMLMSFAGVI-------WTMSGYDSPFHLSEECSNASVAAPRAIVMTSA------FGG 289

  Fly   297 -VSTVLTMMLPYFEQDEKAPL------PHVFRINGWHVAEY--VVSIGAMFGLCSSMM--GAMFP 350
             |..:|.:.:.|...|..|.:      |.|..:.  .|..|  .|::.::..:||.||  |.|..
pombe   290 IVGWLLNLCIAYTIVDVNAAMNDDLGQPFVVYLR--QVCNYKTTVALTSLTVICSFMMGQGCMVA 352

  Fly   351 LPRIVFAMSNDGL--LFKFLGDISEKYKTPFKGTMITGMLTGILAA--VFNLSQLVN-MMSIGTL 410
            ..|:.::.:.||:  ..|:|..:.::.||| ...:...::.|||..  :|.....:| :.|:|.:
pombe   353 ASRVTYSYARDGVFPFSKYLAIVDKRTKTP-NVCVWMNVVVGILCCLLIFAGEAAINAIFSVGAI 416

  Fly   411 LAY 413
            .|:
pombe   417 AAF 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5535	NP_649019.2	2A0303	20..585	CDD:273330	110/458 (24%)
CG5535	NP_649019.2	AA_permease_C	535..585	CDD:290617
SPCC584.13	NP_588218.1	2A0304	28..511	CDD:273331	108/453 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2006
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940