DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5535 and SPCPB1C11.02

DIOPT Version :9

Sequence 1:	NP_649019.2	Gene:	CG5535 / 39990	FlyBaseID:	FBgn0036764	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	NP_588425.1	Gene:	SPCPB1C11.02 / 2539031	PomBaseID:	SPCPB1C11.02	Length:	505	Species:	Schizosaccharomyces pombe

Alignment Length:	437	Identity:	95/437 - (21%)
Similarity:	182/437 - (41%)	Gaps:	89/437 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 LAKVLSAFDLTALGIGSTLGVGVYVLAGEVSKQYAGPA-VVVSFLIAAIASIFAGLCYAEFGARV 99
            |.:.|||..:..|..|..:|.|:::..|. |...:||| :::||.:..::.....|...|....:
pombe    14 LHRSLSASQIQMLAFGGIIGTGLFLGIGS-SLAESGPASLLISFSVLGVSVYCTMLALGEMSVYM 77

  Fly   100 PKAGS--AYIYSYVTIGEFIAFLIGWNLILEYAIGSASVVKGLST------YLDQLCGNPMS--- 153
            |.|||  .|:..||  .|.::|.:.||..|...|..||.|  |:|      :|....|:|:|
pombe    78 PVAGSFCTYVGRYV--DEALSFSLTWNYWLNDTIALASHV--LATRLVVDFWLIPTEGDPVSASL 138

  Fly   154 ---------------SFLGTHMPLNIEGMGAYPDLFAFVVTI-LFSLAIAVGAKESTRVNNVFTM 202
                           :.|..::.||:..:|.:.::..::.:| :|::|..:       ||.:  :
pombe   139 SLPPWKEAVRIITPITSLSANIILNMLPVGGFGEIEYWLSSIKVFTVAAFI-------VNGI--L 194

  Fly   203 LNLGVVLFVIIAGLFKVSSSN---------WSIPKSQVPEGYGDGGFMPYGVSGIIKGAAVCFYG 258
            .||||              :|         |.           |.|....|:.|:|.......:.
pombe   195 CNLGV--------------NNEKKFIGFRYWK-----------DPGAFNNGIIGVISSFVNAAFA 234

  Fly   259 FIGFDCIATAGEEAKNPKKSIPFAVIVSLAMIFLAYFGVSTVLTMMLPY----FEQD--EKAPLP 317
            :.|.:.||....|||:|..::|.|:..:...:.|.|.....|:.:.|||    .:.|  ..:|..
pombe   235 YAGTESIALTAGEAKSPITTLPKAIRFTAHRVLLLYIISVLVVGINLPYNTPGLDGDSVRMSPFT 299

  Fly   318 HVFRINGWHVAEYVVSIGAMFGLCSSMMGAMFPLPRIVFAMSNDGLLFKFLGDISEKYKTPFKGT 382
            .||:..|...|..::::..:....|:...:::...|::::::..|...|.....: |:..|:...
pombe   300 FVFKKFGVPGAASIMNLVILSSALSAGNHSLYAGTRLLYSLAKSGHAPKVFSKCN-KHGIPWLSV 363

  Fly   383 MITGMLTGILAAVFNLSQ-----LVNMMSIGTLLAYSMVASCVLMLR 424
            :.|. .|.||..:.:.:.     |:|::::...:::..:|...|..|
pombe   364 LATS-ATAILCLMSSQAGKTWGFLLNVIAVSNQISWIFIAVSSLRFR 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5535	NP_649019.2	2A0303	20..585	CDD:273330	95/437 (22%)
CG5535	NP_649019.2	AA_permease_C	535..585	CDD:290617
SPCPB1C11.02	NP_588425.1	2A0310	16..485	CDD:273334	94/435 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2006
SonicParanoid	1	1.000	-	-		X81
TreeFam	0	0.000	Not matched by this tool.
	4	3.940