Protein Alignment CG5535 and AU018091

DIOPT Version :10

• Sequence 1: NP_649019.2
• Gene: CG5535 / 39990
• FlyBaseID: FBgn0036764
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_001004153.2
• Gene: AU018091 / 245128
• MGIID: 2142124
• Length: 684
• Species: Mus musculus
• Alignment Length: 653
• Identity: 268/653 - (41%)
• Similarity: 391/653 - (59%)
• Gaps: 63/653 - (9%)

  Fly    13 WSVTNAF-RVLTRKKPL--EDSNESKLAKVLSAFDLTALGIGSTLGVGVYVLAGEVSKQYAGPAV 74
            |...:.| :.|.|::||  .:.:||.|::.|:..||.:||:|||||.|||||||||:::.|||::
Mouse    52 WQNLHQFGQKLVRRRPLAANEQSESSLSRCLTTLDLVSLGVGSTLGAGVYVLAGEVAREKAGPSI 116

  Fly    75 VVSFLIAAIASIFAGLCYAEFGARVPKAGSAYIYSYVTIGEFIAFLIGWNLILEYAIGSASVVKG 139
            ::.|||||::|:.:||||||||||||.:||||:|||||:|:.:||:.||||||.|.||:|||.:.
Mouse   117 IICFLIAALSSVMSGLCYAEFGARVPCSGSAYLYSYVTVGQLLAFITGWNLILNYVIGAASVARA 181

  Fly   140 LSTYLDQLCGNPMSSFLGTHMPLNIEG-MGAYPDLFAFVVTILFSLAIAVGAKESTRVNNVFTML 203
            .|...|.|.||.:|..:.|..|:.:.. :..|||.||..:.|:.:..:|:||:||..|..|||.:
Mouse   182 WSAAFDGLIGNHISQAMQTTFPIQVPSFLAKYPDFFALGLVIVLTGILALGARESALVTRVFTGV 246

  Fly   204 NLGVVLFVIIAGLFKVSSSNWSIPKSQVPEGY----------------GDGGFMPYGVSGIIKGA 252
            ||.|:.||.::||......||.:.:    :.|                |.|||||:|:.||::|.
Mouse   247 NLLVLCFVSLSGLINGKLHNWQLTE----DDYKLALLESNNTDSLGPMGSGGFMPFGLKGILRGT 307

  Fly   253 AVCFYGFIGFDCIATAGEEAKNPKKSIPFAVIVSLAMIFLAYFGVSTVLTMMLPYFEQDEKAPLP 317
            |.||:.||||||||:.||||:.|::|||..::.||.:.||.|||||..||:|:||::.:..:|||
Mouse   308 ATCFFAFIGFDCIASTGEEARCPQRSIPLGIVTSLFICFLMYFGVSGALTLMIPYYQININSPLP 372

  Fly   318 HVFRINGWHVAEYVVSIGAMFGLCSSMMGAMFPLPRIVFAMSNDGLLFKFLGDISEKYKTPFKGT 382
            ..|...||..|.|.|::|.:..|.||::|::||:||:|::|:.|||||:.|..:..:..||...|
Mouse   373 QAFIHVGWGPARYAVAVGTLCALSSSLIGSIFPVPRVVYSMAEDGLLFRKLAYVHPRTHTPVLAT 437

  Fly   383 MITGMLTGILAAVFNLSQLVNMMSIGTLLAYSMVASCVLMLRYEVDD------RRESRIVANGRA 441
            ::.|::...:|.:..||.||::.||||||||::|...||:|||:.|.      |.:|...|....
Mouse   438 VLCGIIAAFMAFLVELSDLVDLSSIGTLLAYTLVTFSVLILRYQPDQVLSSCKREKSESAAVELE 502

  Fly   442 TGLEQDRPCALWR-----------RIFNLNGQTVPTKQTSRIVTYSVTLFSLWCMVFSQILTKFE 495
            .|||   |.:...           |...:...|.||.::.|||....:|.....|:...|||::.
Mouse   503 PGLE---PSSCMEPISPEGMPGIARTLCIPTNTTPTLRSGRIVYGCASLLVFLLMLLCLILTQWS 564

  Fly   496 EDLANVTSFDG----IKLVLGTIPLAV-LLLVISRQPTSGVKLSFKVPLVPWLPGISILINIYLM 555
            ..|     |.|    |.:....:.|.| ::.||.|||.|...|.||||.:|.||.:||.:|||||
Mouse   565 TQL-----FSGDPVLIAMAASLLLLTVGVITVIWRQPQSTTPLHFKVPALPVLPALSIFVNIYLM 624

  Fly   556 IKLDILTWIRFSIWIAIGLAIFLAYGIRHSRLRQREQRNNSIAMMRDCSNSALLGGQENSKYSNE 620
            :::...||.||.||:.||.||:..|||:||...:.:|:..:       |:|..|  ||..:::..
Mouse   625 MQMTSGTWFRFGIWMVIGFAIYFGYGIQHSLEEKNDQQPTA-------SSSQTL--QELQEHTPS 680

  Fly   621 VPL 623
            |.|
Mouse   681 VDL 683

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5535	NP_649019.2	2A0303	20..585	CDD:273330	256/605 (42%)
AU018091	NP_001004153.2	2A0303	53..656	CDD:273330	259/614 (42%)