Protein Alignment CG5535 and Slc7a4

DIOPT Version :10

• Sequence 1: NP_649019.2
• Gene: CG5535 / 39990
• FlyBaseID: FBgn0036764
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_001346821.1
• Gene: Slc7a4 / 224022
• MGIID: 2146512
• Length: 700
• Species: Mus musculus
• Alignment Length: 616
• Identity: 235/616 - (38%)
• Similarity: 359/616 - (58%)
• Gaps: 56/616 - (9%)

  Fly     9 GMPSWSVTNAF-RVLTRKKPLEDSN-ESKLAKVLSAFDLTALGIGSTLGVGVYVLAGEVSKQYAG 71
            |:||.:....| :.|.|.||||:|: |:.|.:.||..|||.||:|..:|.|:|||.|.|:|..||
Mouse    69 GLPSTACLARFCQKLNRLKPLEESSMETSLRRCLSTLDLTLLGVGGMVGSGLYVLTGTVAKDMAG 133

  Fly    72 PAVVVSFLIAAIASIFAGLCYAEFGARVPKAGSAYIYSYVTIGEFIAFLIGWNLILEYAIGSASV 136
            |||::|||:||:||:.|.|||||||||||:.||||:::||::||..|||||||::|||.||.|:|
Mouse   134 PAVLLSFLVAAVASLLAALCYAEFGARVPRTGSAYLFTYVSMGEIWAFLIGWNVLLEYLIGGAAV 198

  Fly   137 VKGLSTYLDQLCGNPMSSFLGTHMPL-NIEGMGAYPDLFAFVVTILFSLAIAVGAKESTRVNNVF 200
            .:..|.|||.:..:.:.:|..:|:.: .:..:..|||..|..:.::.|..::.||:.|:.:|:.|
Mouse   199 ARAWSGYLDAIFNHSIRNFTESHLGVWQVPFLAHYPDFLAAGILLVASAFVSCGARVSSWLNHTF 263

  Fly   201 TMLNLGVVLFVIIAGLFKVSSSNWSIPKSQVPEGYGDGGFMPYGVSGIIKGAAVCFYGFIGFDCI 265
            :.::|.|:||:|:.|.......|||..         :|||.|:|.|||:.|.|.|||.|:|||.|
Mouse   264 SAISLIVILFIIVLGFILARPHNWSAE---------EGGFAPFGFSGILAGTATCFYAFVGFDVI 319

  Fly   266 ATAGEEAKNPKKSIPFAVIVSLAMIFLAYFGVSTVLTMMLPYFEQDEKAPLPHVFRINGWHVAEY 330
            |.:.||||||:.::|.|:.:||::...||..||||||:|:|:...|..:.|...|...|:..|.:
Mouse   320 AASSEEAKNPRWAVPMAIAISLSLAAGAYILVSTVLTLMVPWHSLDPDSALADAFYRRGYSWAGF 384

  Fly   331 VVSIGAMFGLCSSMMGAMFPLPRIVFAMSNDGLLFKFLGDISEKYKTPFKGTMITGMLTGILAAV 395
            :|::|::..:.:.::..:|.|||||:||:.|||.|:....:..:.:.|..|.::.|:|..:||.:
Mouse   385 IVAVGSICAMNTVLLSNLFSLPRIVYAMAADGLFFQVFARVHPRTQVPVVGILVFGVLMALLALL 449

  Fly   396 FNLSQLVNMMSIGTLLAYSMVASCVLMLRYEVDDRRESRIVANGRATGLEQDRPCALWRRIFNLN 460
            .:|..||..:||||||||:.||:.:::||::......|..:|:...|..:.|.        |:.:
Mouse   450 LDLEALVQFLSIGTLLAYTFVATSIIVLRFQKASPPSSPCLASPGPTAKKYDS--------FSDH 506

  Fly   461 GQTVPTKQTSR-------------------IVTYSVTLFSLWCMVFSQILTKFEEDLANVTSFDG 506
            .|.|..:|||.                   ....:...::|..:|.|.|      .||.|..|..
Mouse   507 IQLVGAEQTSMSEPGQLRPALKPFLGFLDGCSPGTAVAWALGILVASAI------SLACVLVFGN 565

  Fly   507 IKLVL---GTIPLAVL--------LLVISRQPTSGVKLSFKVPLVPWLPGISILINIYLMIKLDI 560
            ..|.|   |.:.|.|:        |||:........:.:|::||||..|.:|||:|..||:||..
Mouse   566 SDLHLPQWGYVLLLVISGAVFLSSLLVLGAHQQQKKQDTFQIPLVPLTPALSILLNTCLMLKLSY 630

  Fly   561 LTWIRFSIWIAIGLAIFLAYGIRHSRLRQRE 591
            |||:||..|:.:||.::..|||.||:..|||
Mouse   631 LTWLRFIFWLLVGLVVYFGYGIWHSKENQRE 661

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5535	NP_649019.2	2A0303	20..585	CDD:273330	226/596 (38%)
Slc7a4	NP_001346821.1	2A0303	79..657	CDD:273330	229/600 (38%)