Protein Alignment CG5535 and Y53F4B.12

DIOPT Version :10

• Sequence 1: NP_649019.2
• Gene: CG5535 / 39990
• FlyBaseID: FBgn0036764
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_001293550.1
• Gene: Y53F4B.12 / 190214
• WormBaseID: WBGene00013159
• Length: 762
• Species: Caenorhabditis elegans
• Alignment Length: 756
• Identity: 148/756 - (19%)
• Similarity: 264/756 - (34%)
• Gaps: 225/756 - (29%)

  Fly    23 TRKKPLEDSNESKLAKVLSAFDLTALGIGSTLGVGVYVLAGEVSKQYAGPAVVVSFLIAAIASIF 87
            ||:...:....|:.|:.|....:.||....::.:.::::......|.|||:.|::.:.|.:...|
 Worm    11 TRRVDEQFLRHSEWARRLGVPLMVALAGIKSISMMLFIILPFSLTQVAGPSTVLAPIFAFLIIFF 75

  Fly    88 AGLCYAEFGARVPKAGSAYIYSYVTIGEFIAFLIGWNLILEYAIGSASVVKGLSTYLDQLC-GNP 151
            :....:|....:||....|.::|..|||..||:|.|..:::|...:....|..:.:.:.|. |.|
 Worm    76 SAAHLSELSCTMPKNCVQYHFAYAVIGELPAFVIAWISLVDYVAQAGLFCKAWADHFNLLFRGLP 140

  Fly   152 MSSFLGTHMPLNIEGMGAYP--DLFAFVVTILFSLAIAVGAKESTRVNNVFTMLNLGVVLFV--- 211
            ..|.  |....:.:.|...|  ||.. |::.:.:|.:.:.   |.||.....:..|.|.|.:
 Worm   141 AKSL--TFDVFSTDSMLLSPQVDLLT-VLSAIITLCLLLC---SLRVVGTICVSLLAVTLLIAAS 199

  Fly   212 -IIAGLFKVSSSNWSIPKSQVPEGYGDGGFMPYGVSGI---IKGAAVCFYGFIGFDCIATAGEEA 272
             .:...|.....||.  |::         |..:|..|:   |.....|:.|.....|:.   ||.
 Worm   200 CTMVAFFHSDPENWI--KAE---------FFHFGYQGVLYAICALCACYTGIESTSCLL---EET 250

  Fly   273 KNPKKSI----PFAVIVSLAMIFL--AYFGVSTVLTMM--------------------------- 304
            |||:|.|    .|.|:|...:.|:  ..|.:||.:|.:
 Worm   251 KNPRKRISGVLSFLVLVLTTIFFVLSITFSLSTNVTALSEGIMIPEVFSVINIPAAKSSSKHWVR 315

  Fly   305 -LPYFEQDEKAP----LPHVFRI---NGWHVAEYVVSIGAMFGLCSSMMGAMFPLPRIVFAMSND 361
             .|.....|.|.    .|..||.   .|:....|::|:.::..|...::.:..|..|::.|:.:|
 Worm   316 RFPMISPSESATSSSISPSAFRSYYEQGFIRMRYMLSVCSVCALSGGVLASFLPATRVIAALCHD 380

  Fly   362 GLLFKFLGDISEKYKTPFKGTMITGMLTGILAAVFNLSQLVNM--------MSIGTLLAY----- 413
            .|: .:..|.|.  |:|:...::..:|.. |.::...:.|:|.        :.|..||.|
 Worm   381 RLI-PYAKDTST--KSPYFAVLLCTVLVA-LCSMIQKTMLLNFVIFMAPVKLVITILLVYLQHYY 441

  Fly   414 -----------------------------SMVASCVLMLRYEVDDRRESRIVANG---------- 439
                                         |:..|..|:....::|..:...|::.
 Worm   442 PEQIGIPEETSNYKSIGKKRTRVHIDDGVSIDDSVSLIPSRHLEDHDDQSEVSHSTFDTTAFLYM 506

  Fly   440 RATGLEQDRPCALWRR-----IFNLNGQTVPTKQTSRIVT------------------------- 474
            :||.:|.:|   |.:|     :.|...|.|..|..|:..|
 Worm   507 KATKMESER---LQKRLEKEQLENEELQPVLAKSVSQYHTMDPNLKKAKKIKKHAHNCVAEQCGA 568

  Fly   475 --------YSVTLFS-------------------------------------LWCMV---FSQIL 491
                    ..|.||:                                     |:|:|   ||..|
 Worm   569 ENDDDFNSQEVHLFANEEPELPFFSTFSSSAPRPPSPDVSFATFHRSRRLLFLFCVVTCAFSAFL 633

  Fly   492 TKFEEDLANVTSFDGIKLVLGTIPLAVLLLV-ISRQPTSG--VKLSFKVPLVPWLPGISILINIY 553
            ..:.  :..||.:   .|.:|.:.:.|:..| |:|..|:.  .|...||.|.|    .:.|..::
 Worm   634 RNYA--VPTVTCW---MLSIGFVLVIVVFTVNINRLQTNDYLYKKESKVTLFP----TTSLFTLF 689

  Fly   554 LMI-----KLDILTWIRFSIWIAIGLAIFLAYGIRHSRLRQ 589
            :::     .:...|.....:...||:..:..||.|||:.|:
 Worm   690 MLLGSFAGSVPTKTLAHLVVIPLIGILAYFLYGYRHSKHRK 730

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5535	NP_649019.2	2A0303	20..585	CDD:273330	145/750 (19%)
Y53F4B.12	NP_001293550.1	PotE	26..437	CDD:440297	93/434 (21%)