Protein Alignment CG5535 and B0454.6

DIOPT Version :10

• Sequence 1: NP_649019.2
• Gene: CG5535 / 39990
• FlyBaseID: FBgn0036764
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_494428.1
• Gene: B0454.6 / 173650
• WormBaseID: WBGene00015197
• Length: 585
• Species: Caenorhabditis elegans
• Alignment Length: 579
• Identity: 217/579 - (37%)
• Similarity: 345/579 - (59%)
• Gaps: 29/579 - (5%)

  Fly    15 VTNAFRVLTRKKPLE-DSN-ESKLAKVLSAFDLTALGIGSTLGVGVYVLAGEVSKQYAGPAVVVS 77
            |::.::.:||||..| ||: :|.|.:.|...|:|.|.:|..:|.|:|||.|.|.:..|||:::.|
 Worm     2 VSHVWQAITRKKRFEGDSHLDSNLRRCLGLMDITFLALGQMMGAGIYVLTGTVVRNQAGPSIIFS 66

  Fly    78 FLIAAIASIFAGLCYAEFGARVPKAGSAYIYSYVTIGEFIAFLIGWNLILEYAIGSASVVKGLST 142
            |.:|.||::.:...|||||||.|:|||||.|:|:..||..||::||.:.|||.||:|:|.:..|.
 Worm    67 FALAGIAALLSAFSYAEFGARFPRAGSAYTYTYIGFGELWAFIVGWTIPLEYMIGNAAVARSWSA 131

  Fly   143 YLDQLCGNPM-SSFLGTHMPLNIEG--MGAYPDLFAFVVTILFSLAIAVGAKESTRVNNVFTMLN 204
            |.|.:..|.: ::.:|....|:..|  ...|||:.:|::..|.:..||||.|.|..||:.|.:||
 Worm   132 YFDNMLDNYIKNTTIGALGELSEPGGFFSTYPDILSFLLICLCACVIAVGPKVSANVNSSFVVLN 196

  Fly   205 LGVVLFVIIAGLFKVSSSNWSIPKSQVPEGYGDGGFMPYGVSGIIKGAAVCFYGFIGFDCIATAG 269
            :.|:..||::|:.....:||:...|.     |...|.|:|::|.:.|||.||:.:|||:.:||||
 Worm   197 IVVIFIVIVSGICYADFNNWTGTTSD-----GRSMFFPFGLTGTLTGAATCFFSYIGFEVLATAG 256

  Fly   270 EEAKNPKKSIPFAVIVSLAMIFLAYFGVSTVLTMMLPYFEQDEKAPLPHVFRINGWHVAEYVVSI 334
            ||.|:|.::||.|..:|:.:|...|..||:.||:|:||.:....||....|...|.....|::||
 Worm   257 EEVKSPHRTIPVATFLSIGVIMTLYILVSSTLTLMVPYDQVHTTAPFAEAFSARGCTTVMYIISI 321

  Fly   335 GAMFGLCSSMMGAMFPLPRIVFAMSNDGLLFKFLGDISEKYKTPFKGTMITGMLTGILAAVFNLS 399
            ||:.||.::::..:|.|||.|:||::|||:||:|..::...|.|....:|..:|..|:|.:|::.
 Worm   322 GALIGLTNNLVTGVFALPRAVYAMADDGLIFKWLAHVTSSTKVPLNAIVIFTLLNAIIALIFDIE 386

  Fly   400 QLVNMMSIGTLLAYSMVASCVLMLRYEVDDRRESRIVANGRATGLEQDRPCALWRRIFNLNGQTV 464
            .||..:|||||.|||.|:..||:|||:     .:.|..:|:.  ::.....:.|....|. .:::
 Worm   387 ALVEFLSIGTLFAYSFVSGSVLVLRYQ-----SAPIDGDGKR--MDNGGELSSWIPARNF-WESL 443

  Fly   465 PTKQTSRIVTYSVTLFSLWCMVFSQILTKFEEDLANVTS--FDGIKLVLGTIPLAVLLLVISRQP 527
            |. .||..:..:..:.|.:.:.|: ..|.|.|......|  |:|:.:||      |:..::..|.
 Worm   444 PA-GTSISLGVAALIGSFFWLAFT-FRTGFYEHWYGQISIGFNGLLIVL------VMAFILGHQQ 500

  Fly   528 TSGVKLSFKVPLVPWLPGISILINIYLMIKLDILTWIRFSIWIAIGLAIFLAYGIRHSR 586
            .| ::.|||||.||:||.:|:|:|:::|..|...||||..:|:.:||.|:.:||||||:
 Worm   501 NS-LETSFKVPFVPFLPCLSLLVNVFMMAYLTTATWIRLFVWMGVGLLIYFSYGIRHSK 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5535	NP_649019.2	2A0303	20..585	CDD:273330	214/571 (37%)
B0454.6	NP_494428.1	2A0303	7..559	CDD:273330	216/574 (38%)