DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5535 and Slc7a9

DIOPT Version :9

Sequence 1:	NP_649019.2	Gene:	CG5535 / 39990	FlyBaseID:	FBgn0036764	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	NP_446381.1	Gene:	Slc7a9 / 116726	RGDID:	619905	Length:	487	Species:	Rattus norvegicus

Alignment Length:	427	Identity:	96/427 - (22%)
Similarity:	179/427 - (41%)	Gaps:	70/427 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 SNESK---LAKVLSAFDLTALGIGSTLGVGVYVLAGEV--SKQYAGPAVVVSFLIAAIASIFAGL 90
            |.|.|   |.|.:.......:.:|:.:|.|:::....|  :.:..||.:::......:|::.| |
  Rat    18 STEPKTTSLQKEVGLLSGICIIVGTIIGSGIFISPKSVLANTESVGPCLIIWAACGVLATLGA-L 81

  Fly    91 CYAEFGARVPKAGSAYIYSYVTIGEFIAFLIGWNLILEYAIGSASVVKGLSTYLDQLCGNPMSSF 155
            |:||.|..:.|:|..|.|.....|...|:|..|..::.....|.:::  ..::.:.:|.   :.:
  Rat    82 CFAELGTMITKSGGEYPYLMEAFGPIPAYLFSWTSLIVMKPSSFAII--CLSFSEYVCA---AFY 141

  Fly   156 LGTHMPLNIEGMGAYPDLFAFVVTILFSLAI-------AVGAKESTRVNNVFTMLNLGVVLFVII 213
            ||...|             |.||.:|.:.||       |:..:..:.|.||||...|.:|..:||
  Rat   142 LGCRPP-------------AVVVKLLAAAAILLITTVNALSVRLGSYVQNVFTAAKLVIVAIIII 193

  Fly   214 AGLFKVSSSNW-----SIPKSQVPEGYGDGGFMPYGVSGIIKGAAVCFY----GFIGFDCIATAG 269
            :||..::..|.     |...||...|                ..::.||    .:.|::.:....
  Rat   194 SGLVLLAQGNVKNFQNSFEGSQTSVG----------------SISLAFYNGLWAYDGWNQLNYIT 242

  Fly   270 EEAKNPKKSIPFAVIVSLAMIF-------LAYFGVSTVLTMMLPYFEQDEKAPLPHVFRINGWHV 327
            ||.:||.:::|.|:::.:.::.       :|||.|.|...::     |.:...:....|:  .:.
  Rat   243 EELRNPYRNLPMAIVIGIPLVTVCYILMNIAYFTVMTPTELL-----QSQAVAVTFGDRV--LYP 300

  Fly   328 AEYVVSIGAMFGLCSSMMGAMFPLPRIVFAMSNDGLLFKFLGDISEKYKTPFKGTMITGMLTGIL 392
            |.:||.:...|....:..|..|...|:::....:|.:.|.|..||.|..||....:..|::..|.
  Rat   301 ASWVVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVKRLTPAPALVFYGIIAIIY 365

  Fly   393 AAVFNLSQLVNMMSIGTLLAYSMVASCVLMLRYEVDD 429
            ....:::.|||..|....|.|.|....::::|:...|
  Rat   366 IIPGDINSLVNYFSFAAWLFYGMTILGLVVMRFTRKD 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5535	NP_649019.2	2A0303	20..585	CDD:273330	96/427 (22%)
CG5535	NP_649019.2	AA_permease_C	535..585	CDD:290617
Slc7a9	NP_446381.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..23		2/4 (50%)
Slc7a9	NP_446381.1	2A0308	13..484	CDD:273332	96/427 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351263
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940