Protein Alignment CG5535 and slc7a11

DIOPT Version :10

• Sequence 1: NP_649019.2
• Gene: CG5535 / 39990
• FlyBaseID: FBgn0036764
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: XP_002932094.2
• Gene: slc7a11 / 100496726
• XenbaseID: XB-GENE-960114
• Length: 500
• Species: Xenopus tropicalis
• Alignment Length: 576
• Identity: 123/576 - (21%)
• Similarity: 224/576 - (38%)
• Gaps: 121/576 - (21%)

  Fly    13 WSVT---NAFRVL--TRKKPLEDSNESKLAKVLSAFDLTALGIGSTLGVGVYVL-------AGEV 65
            :|||   ::.|:|  ..||..|...:..|.|.::.....::.||:.:|.|:::.       .|.|
 Frog    10 YSVTKGKDSRRMLPSADKKMSEKGEKVVLKKKVTLLRGISIIIGTIIGAGIFISPKGILQNTGSV 74

  Fly    66 SKQYAGPAVVVSFLIAAIASIFAGLCYAEFGARVPKAGSAYIYSYVTIGEFIAFLIGWNLILEYA 130
                 |.::|| :....|.|:|..|||||.|..:.|:|..|.|.....|...||:..|..:|
 Frog    75 -----GMSLVV-WTACGILSLFGALCYAELGTCIKKSGGHYTYILEAFGPLPAFIRVWVELL--- 130

  Fly   131 IGSASVVKGLSTYLDQLCGNPMSSFLGTHM--PLNIEGMGAYPDLFAFVVTILFSLAI----AVG 189
                 |::..:|.:       :|...|.::  |..|:  ...|||...:||.|....:    :|.
 Frog   131 -----VIRPAATAV-------ISLAFGRYILEPFFIQ--CEIPDLAIKLVTALGITIVMVLNSVS 181

  Fly   190 AKESTRVNNVFTMLNLGVVLFVIIAG---LFKVSSSNWSIPKSQVPEGYGDGGFMPYGVSGIIKG 251
            ...|.|:....|...|..:|.:|:.|   |.|..:.|:.            ..|:...||  :.|
 Frog   182 VSWSARIQIFLTFCKLIAILIIIVPGVLQLIKGETQNFK------------DAFIGKDVS--VMG 232

  Fly   252 AAVCF----YGFIGFDCIATAGEEAKNPKKSIPFAVIVSLAMIFLAYF--GVSTVLTMMLPYFEQ 310
            ..:.|    |.:.|:..:....||.:||:|::|.|:.:|:|::.:.|.  .|:...|:.......
 Frog   233 LPLAFYSGMYAYAGWFYLNFVTEEVENPEKNVPLAICISMAIVTVGYVLTNVAYYTTISAEELVL 297

  Fly   311 DEKAPLPHVFRING-WHVAEYVVSIGAMFGLCSSMMGAMFPLPRIVFAMSNDGLLFKFLGDISEK 374
            .....:.:..|:.| :.:|..:....:.||   ||.|.:|.:.|:.:..|.:|.|.:.|..|..:
 Frog   298 SSAVAVTYAERLFGSFSLAVPIFVALSCFG---SMNGGVFAVSRMFYVASREGHLPEILSMIHVR 359

  Fly   375 YKTPFKGTMITGMLTGILAAVFNLSQLVNMMSIGTLLAYSMVASCVLMLRYEVDDRRESRIVANG 439
            ..||....::...||.::....::..|:|..|....|...:..:.::.|||:..
 Frog   360 KHTPLPAVIVLLPLTMVMLFTGDIYSLLNFFSFVRWLFIGLAVAGLIYLRYKRP----------- 413

  Fly   440 RATGLEQDRPCALWRRIFNLNGQTVPTKQTSRIVTYSVTLFSLWCMVFSQILTKFEEDLANVTSF 504
                 |..||                    .::..:...|||..|: |...|:.:.:.   :.:.
 Frog   414 -----EMHRP--------------------FKVPIFIPALFSFTCL-FMVALSLYSDP---INTG 449

  Fly   505 DGIKLVLGTIPLAVLLLVISRQPTSGVKLSFKVPLVPWLPGISILINIYLMIKLDI 560
            .|..:.|..:|...|.::...:|             .|....:....:.|.|.|::
 Frog   450 IGFAITLTGVPAYYLFVIWDNKP-------------EWFRTFTDRTTLMLQILLEV 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5535	NP_649019.2	2A0303	20..585	CDD:273330	120/566 (21%)
slc7a11	XP_002932094.2	2A0308	17..492	CDD:273332	120/567 (21%)