DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5535 and slc7a13

DIOPT Version :9

Sequence 1:	NP_649019.2	Gene:	CG5535 / 39990	FlyBaseID:	FBgn0036764	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	XP_002941804.3	Gene:	slc7a13 / 100495712	XenbaseID:	XB-GENE-995917	Length:	489	Species:	Xenopus tropicalis

Alignment Length:	435	Identity:	109/435 - (25%)
Similarity:	189/435 - (43%)	Gaps:	56/435 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 MPSWSVT----NAFRVLTRKKPLEDSNES-KLAKVLSAFDLTALGIGSTLGVGVYVLAGEVSKQY 69
            ||....|    |..|:         :|:| .|.:.|..||.|...:|..:|.|::|....| .||
Frog     1 MPEMETTADHENTLRI---------ANKSVSLRRTLGFFDGTCFLVGIIVGAGIFVSPTGV-LQY 55

  Fly    70 AGPAVVVSFLIAAIASI---FAGLCYAEFGARVPKAGSAYIYSYVTIGEFIAFLIGWNLILEYAI 131
            |...|.|:..|.|...|   ...|||||.|:.:|.||..|.:....:|.|.||:..|.||| :..
Frog    56 AQLNVGVALCIWAACGILVMMGALCYAELGSALPYAGGEYYHVKQALGPFPAFIFIWTLIL-FIR 119

  Fly   132 GSASVVKGLSTYLDQLCGNPMSSFLGTHMPLNIEGMGAYPDLFAFVV--TILFSLAI--AVGAKE 192
            .:::..:.|  ...:....|..|...|            |:|...:|  .:|:.|.|  ...||.
Frog   120 PASNAARAL--MFAEYATRPFFSGCPT------------PELLKKIVALAVLWVLGIINTKSAKT 170

  Fly   193 STRVNNVFTMLNLGVVLFVIIAGLFKVSSSNWSIPKSQVPEGYGDGGFMPYGVSGIIKGAAVC-- 255
            :|.|.||||:|.:..::.::..||.:::.      |:::| |:....|.    |..:..|.:.
Frog   171 TTWVQNVFTVLKMLALILIVTCGLKELAE------KTEIP-GHLQNAFS----SPDLNAAQIAES 224

  Fly   256 ----FYGFIGFDCIATAGEEAKNPKKSIPFAVIVSLAMIFLAYFGVS-TVLTMMLPYFEQDEKAP 315
                .|.:.|::.:....||.|||.|:||...|.:::::.:.|..|: :.||::.|. |....|.
Frog   225 FFQGLYAYGGWNYLNYIAEEIKNPTKNIPLCTITAVSVVIVFYLLVNISYLTVLTPK-EIVSSAA 288

  Fly   316 LPHVFRINGWHVAEYVVSIGAMFGLCSSMMGAMFPLPRIVFAMSNDGLLFKFLGDISEKYKTPFK 380
            :...:......:..:::.:.....:..::.|.||.|.|:.:|.|.:|.|...|..:...:.||..
Frog   289 VSVTWADRVIPMVAWIIPVSVAISIFGALNGGMFMLGRLNYAGSKEGHLPSLLSMLHVNHLTPAP 353

  Fly   381 GTMITGMLTGILAAVFNLSQLVNMMSIGTLLAYSMVASCVLMLRY 425
            ..:::.::..|.....:|..|.|.....|.|...:....:::|||
Frog   354 AMILSTIIASIFVIPSDLLSLTNYFGFSTWLLVGLTVISLIVLRY 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5535	NP_649019.2	2A0303	20..585	CDD:273330	105/421 (25%)
CG5535	NP_649019.2	AA_permease_C	535..585	CDD:290617
slc7a13	XP_002941804.3	2A0308	17..477	CDD:273332	104/410 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910