DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5535 and slc7a10

DIOPT Version :9

Sequence 1:	NP_649019.2	Gene:	CG5535 / 39990	FlyBaseID:	FBgn0036764	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	XP_002935839.2	Gene:	slc7a10 / 100494333	XenbaseID:	XB-GENE-987435	Length:	530	Species:	Xenopus tropicalis

Alignment Length:	441	Identity:	100/441 - (22%)
Similarity:	184/441 - (41%)	Gaps:	70/441 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 MPSWSVTNAFRVLTRKKPLEDSNESKLAKVLSAFDLTALGIGSTLGVGVYVLAGEVSKQ--YAGP 72
            :|:..:.|.    |...|...:.:..|.|.:......|:.||:.:|.|:::....|.:.  ..|.
Frog    21 VPTQHIPND----TTTSPESPTEKVTLKKEIGLISACAIIIGNIIGSGIFISPKGVLEHTGSVGL 81

  Fly    73 AVVVSFLIAAIASIFAGLCYAEFGARVPKAGSAYIYSYVT--IGEFIAFLIGWNLIL-EYAIGSA 134
            |:::..|...:|:: ..|||||.|..:||:|..  |||||  .|....||:.|:.:| .|....|
Frog    82 ALIIWVLGGGVAAL-GSLCYAELGVTIPKSGGD--YSYVTEIFGGLAGFLLLWSTVLIMYPTSLA 143

  Fly   135 SVVKGLSTYLDQLCGNPMSSFLGTHMPLNIEGMGAY--PDLFAFVVTILFSLAIAVGAKESTRVN 197
            .:....|.|:.|              |:..|.:..|  ..:.:.|..:|.:...:...:.:||:.
Frog   144 VITLTFSNYVLQ--------------PVFPECIPPYDASRVLSIVCLLLLTWVNSSSVRWATRIQ 194

  Fly   198 NVFT---MLNLGVVLFVIIAGLFK-----VSSSN----WSIPKSQVPEGYGDGGFMPYGVSGIIK 250
            ::||   :|.||:::.|....:||     :..||    |.||                    .:.
Frog   195 DIFTAGKLLALGLIIVVGFMQIFKGNYEELKPSNAFNFWMIP--------------------TVG 239

  Fly   251 GAAVCF----YGFIGFDCIATAGEEAKNPKKSIPFAVIVSLAMIFLAY-FGVSTVLTMMLPYFEQ 310
            ..|:.|    :.|.|::.:....||..:|::::|.|:.:|:.::...| |......|.|.|....
Frog   240 QLALAFLQASFAFSGWNFLNYVTEEMVDPRRNLPRAIFLSIPLVTFVYTFTNIAYFTAMSPQELM 304

  Fly   311 DEKAPLPHVF--RINGWHVAEYVVSIGAMFGLCSSMMGAMFPLPRIVFAMSNDGLLFKFLGDISE 373
            ...| :...|  ::.|:.  .:::.:.........:.|.:|...|:.|:.:.:|.|...|..|..
Frog   305 SSNA-VAVTFGEKLLGYF--SWIMPVSVALSTFGGINGYLFTSSRLCFSGAREGHLPSLLAMIHF 366

  Fly   374 KYKTPFKGTMITGMLTGILAAVFNLSQLVNMMSIGTLLAYSMVASCVLMLR 424
            ||.||....::....|.|:..|.:...|:|.:|....|.|.:....:::||
Frog   367 KYCTPVPALLVCCGATIIIMLVGDTYTLINYVSFINYLCYGVTIMGLIVLR 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5535	NP_649019.2	2A0303	20..585	CDD:273330	98/431 (23%)
CG5535	NP_649019.2	AA_permease_C	535..585	CDD:290617
slc7a10	XP_002935839.2	2A0308	39..504	CDD:273332	96/419 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920