Protein Alignment CG5535 and slc7a2.1

DIOPT Version :9

• Sequence 1: NP_649019.2
• Gene: CG5535 / 39990
• FlyBaseID: FBgn0036764
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: XP_004911248.1
• Gene: slc7a2.1 / 100485546
• XenbaseID: XB-GENE-994549
• Length: 657
• Species: Xenopus tropicalis
• Alignment Length: 656
• Identity: 292/656 - (44%)
• Similarity: 415/656 - (63%)
• Gaps: 57/656 - (8%)

  Fly    20 RVLTRKK--PLEDSNESKLAKVLSAFDLTALGIGSTLGVGVYVLAGEVSKQYAGPAVVVSFLIAA 82
            |.:.|:|  .|:...:|||.:.||..||.|||:|||||.|||||||||:|..:||::||||||||
 Frog    12 RCILRRKIVTLDSLEDSKLCRCLSTLDLVALGVGSTLGAGVYVLAGEVAKANSGPSIVVSFLIAA 76

  Fly    83 IASIFAGLCYAEFGARVPKAGSAYIYSYVTIGEFIAFLIGWNLILEYAIGSASVVKGLSTYLDQL 147
            :||:.||||||||||||||.||||:|:|||:||..||:.||||||.|.||::||.:..|...|:|
 Frog    77 LASVMAGLCYAEFGARVPKTGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDEL 141

  Fly   148 CGNPMSSFLGTHMPLNIEGMGAYPDLFAFVVTILFSLAIAVGAKESTRVNNVFTMLNLGVVLFVI 212
            .|..:..|..|:..:|..|:..|||:||..:.:|.|..::.|.|||..||.|||.:|:.|:|||:
 Frog   142 LGKRIGQFFSTYFRMNSPGLAEYPDIFAVFLILLLSGLLSFGVKESAWVNKVFTAVNVLVLLFVM 206

  Fly   213 IAGLFKVSSSNWSIPKS----------------QVPEGYGDGGFMPYGVSGIIKGAAVCFYGFIG 261
            |||..|....||.|.:|                .|...||.|||||||::|::.|||.|||.|:|
 Frog   207 IAGFVKGDLQNWKITESFLQNISATDGNSVSYDNVTSLYGAGGFMPYGLTGMLAGAATCFYAFVG 271

  Fly   262 FDCIATAGEEAKNPKKSIPFAVIVSLAMIFLAYFGVSTVLTMMLPYFEQDEKAPLPHVFRINGWH 326
            ||||||.|||.:||:::||..::.||.:.|:||||||..||:|:|||:.|||:|||..|...||.
 Frog   272 FDCIATTGEEVRNPQRAIPIGIVASLLICFMAYFGVSAALTLMMPYFKLDEKSPLPVAFEYVGWG 336

  Fly   327 VAEYVVSIGAMFGLCSSMMGAMFPLPRIVFAMSNDGLLFKFLGDISEKYKTPFKGTMITGMLTGI 391
            .|:|||::|::..|.:|::|::||:||:::||:.||||||.|..||.:.|||...|:.:|.:..:
 Frog   337 PAKYVVAVGSLCALSTSLLGSIFPMPRVIYAMAEDGLLFKSLAKISPRTKTPVIATLSSGAVAAV 401

  Fly   392 LAAVFNLSQLVNMMSIGTLLAYSMVASCVLMLRYE-----------------VDDRRESRIVANG 439
            :|.:|:|..||:|||||||||||:||:|||:|||:                 ....|||  :.|.
 Frog   402 MAFLFDLKALVDMMSIGTLLAYSLVAACVLILRYQPGLGYEIPKGNAEKEMLSSSERES--MMNE 464

  Fly   440 RATGLEQDRPCALWRRIFNLNGQTVPTKQTSRIVTYSVTLFSLWCMVFSQILTKFEEDLANVTSF 504
            ....:..|:..:..|.   :|..:|||:|::.:|:..|.|.:|.....|.:.|...:.:|::..:
 Frog   465 SQISILHDKSSSFHRL---MNPPSVPTEQSASLVSSLVGLLALIICALSVLTTYGVQAIADIEVW 526

  Fly   505 DGIKLVLGTIPLAVLLLVISRQPTSGVKLSFKVPLVPWLPGISILINIYLMIKLDILTWIRFSIW 569
            ....||:..:.:.:::::|.|||.:..|::|.||.:|.||..|:|:|:|||::|...||||||||
 Frog   527 SVALLVVFIVLICLIVMIIWRQPQNKHKITFMVPFLPVLPVFSVLVNVYLMVQLSGDTWIRFSIW 591

  Fly   570 IAIGLAIFLAYGIRHS------RLRQREQRNNSIAMMRDCSNSALLGG----QENSKYSNEVPLI 624
            :.||..|:.|||||||      ::...|...:|     |.|.:....|    :||:|.|:.  .|
 Frog   592 MVIGFLIYFAYGIRHSVEGKSKKVEDEEDEEDS-----DGSPTEEKTGKENEEENAKESDH--FI 649

  Fly   625 LMHSTS 630
            |...||
 Frog   650 LHERTS 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5535	NP_649019.2	2A0303	20..585	CDD:273330	277/599 (46%)
		AA_permease_C	535..585	CDD:290617	29/49 (59%)
slc7a2.1	XP_004911248.1	2A0303	7..609	CDD:273330	279/601 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	459	1.000	Domainoid score	I483
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	547	1.000	Inparanoid score	I1130
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D421901at33208
OrthoFinder	1	1.000	-	-		FOG0000131
OrthoInspector	1	1.000	-	-		mtm9394
Panther	1	1.100	-	-	O	PTHR43243
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X81
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.160