DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5535 and slc7a8b

DIOPT Version :9

Sequence 1:	NP_649019.2	Gene:	CG5535 / 39990	FlyBaseID:	FBgn0036764	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	XP_001346314.3	Gene:	slc7a8b / 100007990	ZFINID:	ZDB-GENE-030616-586	Length:	501	Species:	Danio rerio

Alignment Length:	504	Identity:	115/504 - (22%)
Similarity:	199/504 - (39%)	Gaps:	90/504 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 LTALGI--GSTLGVGVYVL-------AGEVSKQYAGPAVVVSFLIAAIASIFAGLCYAEFGARVP 100
            |:|.||  |:.:|.|::|.       :|.|     |.|::|..|...|.:|.| |||||.|..:|
Zfish    33 LSACGIVVGNIIGSGIFVSPKGVLENSGSV-----GLALIVWILTGIITAIGA-LCYAELGVTIP 91

  Fly   101 KAGSAYIYSYVTIGEFIAFLIGWNLILE-YAIGSASVVKGLSTYLDQLCGNPMSSFLGTHMPLNI 164
            |:|..|.|.....|....||..|..:|. |....|.:....:.|..|    |:  |.....|...
Zfish    92 KSGGDYSYVNDIFGGLAGFLRLWIAVLVIYPTNQAVIALTFANYALQ----PL--FPSCFPPERA 150

  Fly   165 EGMGAYPDLFAFVVTILFSLAIAVGAKESTRVNNVFT---MLNLGVVLFVIIAGLFKVSSSN--W 224
            .|      |.|.|..:|.:.......:.:|||.:|||   :|.||:   :||.|:.::...:  |
Zfish   151 LG------LLAAVCLLLLTWINCSSVRWATRVQDVFTTGKLLALGL---IIIMGIVQICKGHFYW 206

  Fly   225 SIPKSQVPEGYGDGGFMPYGVSGIIKGAAVCFYGFIGFDCIATAGEEAKNPKKSIPFAVIVSLAM 289
            ..|:      :......||.:..|........:.:.|::.:....||..:|.:::|.|:.:|:.:
Zfish   207 LEPE------HAFHPLQPYDMGRIALAVLQGSFAYAGWNFLNYVTEELIDPYRNLPRAIFISIPL 265

  Fly   290 IFLAYFGVS-TVLTMMLPYFEQDEKAPLPHVFRINGWHVAEYVVSIGAMFGLCSSMMGAMFPLPR 353
            :...|...: ..:|.|.|. |......:...|......|..:::.|.........:.|::|...|
Zfish   266 VTFVYVSANIAYVTAMSPQ-ELLASNAVAVTFGEKLLGVMSWLMPISVALSTFGGVNGSLFTSSR 329

  Fly   354 IVFAMSNDGLLFKFLGDISEKYKTPFKGTMITGMLTGILAAVFNLSQLVNMMSIGTLLAYSMVAS 418
            :.||.:.:|.|.:.|..|.....||....:||.:.|.::..|.::..|:|.:.....|.|.:..:
Zfish   330 LFFAGAREGHLPRLLAMIHVNRCTPIPALLITCISTLLMLCVSDIYTLINYVGFINYLFYGVTVA 394

  Fly   419 CVLMLRYEVDDRRESRIVANGRATGLEQDRPCAL---WRRIFNLNGQTVPTKQTSRIVTYSVTLF 480
            ..::||.     ||..|.           ||..:   |..:|                    .:|
Zfish   395 GQIVLRI-----REPDIY-----------RPIKVSLAWPAVF--------------------LIF 423

  Fly   481 SLWCMVFSQILTKFEEDLANVTSFDGIKLVLGTIPLAVLLLVISRQPTS 529
            ..:.::||    .:.|.   |....|:.::|..:|:.:..:....:|.|
Zfish   424 WAFLLIFS----LYSEP---VVCCIGLAIMLSGVPVYLFGIYWENKPKS 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5535	NP_649019.2	2A0303	20..585	CDD:273330	115/504 (23%)
CG5535	NP_649019.2	AA_permease_C	535..585	CDD:290617
slc7a8b	XP_001346314.3	AA_permease_2	9..488	CDD:330980	115/504 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593028
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.850