Protein Alignment CG5535 and slc7a3b

DIOPT Version :10

• Sequence 1: NP_649019.2
• Gene: CG5535 / 39990
• FlyBaseID: FBgn0036764
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: XP_001342962.3
• Gene: slc7a3b / 100003376
• ZFINID: ZDB-GENE-120813-6
• Length: 698
• Species: Danio rerio
• Alignment Length: 626
• Identity: 280/626 - (44%)
• Similarity: 400/626 - (63%)
• Gaps: 67/626 - (10%)

  Fly    20 RVLTRKKPLEDSN-ESKLAKVLSAFDLTALGIGSTLGVGVYVLAGEVSKQYAGPAVVVSFLIAAI 83
            ::|.|::.|:||. ||..|:.|:..||.|||:|:|||.|||||||||:::.||||:|:||||||:
Zfish    63 KMLLRRRVLDDSPVESHFARCLTTLDLIALGVGATLGAGVYVLAGEVAREKAGPAIVLSFLIAAL 127

  Fly    84 ASIFAGLCYAEFGARVPKAGSAYIYSYVTIGEFIAFLIGWNLILEYAIGSASVVKGLSTYLDQLC 148
            :|:.||||||||||||||.||||:|||||:||..||:.||||||.|.||:|||.:..|...|.|.
Zfish   128 SSVLAGLCYAEFGARVPKTGSAYVYSYVTVGEIWAFITGWNLILSYVIGTASVARAWSATFDSLL 192

  Fly   149 GNPMSSFLGTHM--PLNIEGMGAYPDLFAFVVTILFSLAIAVGAKESTRVNNVFTMLNLGVVLFV 211
            ...:|:|....|  |.....:..|||:||.::.:|.:..:|.|..||..||.:||.:||.|:.||
Zfish   193 AQKISTFFKAFMSFPDTQNVLAKYPDVFALILVMLLTGLLAFGVSESALVNKIFTGINLVVLTFV 257

  Fly   212 IIAGLFKVSSSNWSIP------------KSQVPEGYGDGGFMPYGVSGIIKGAAVCFYGFIGFDC 264
            ||:|..|..::||::.            ..::.:.:|.|||.|:|::|::.|||.|||.|:||||
Zfish   258 IISGFVKGDTANWNLTVEDYINRTNITGAQKIEKEFGSGGFAPFGLNGVLSGAATCFYAFVGFDC 322

  Fly   265 IATAGEEAKNPKKSIPFAVIVSLAMIFLAYFGVSTVLTMMLPYFEQDEKAPLPHVFRINGWHVAE 329
            |||..||||||.:|||..::.||.:.|.||||||..||:|:||:..|:.:|||..|...||..|.
Zfish   323 IATTSEEAKNPMRSIPIGIVASLLICFFAYFGVSAALTLMMPYYMLDKHSPLPQAFDYVGWGPAR 387

  Fly   330 YVVSIGAMFGLCSSMMGAMFPLPRIVFAMSNDGLLFKFLGDISEKYKTPFKGTMITGMLTGILAA 394
            |:||:|::..|.:|::|:|||:||:::||:.|||||:||..:.:|.|||...|:::|::..::|.
Zfish   388 YIVSVGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFRFLSRMHKKTKTPALATLVSGIVAALMAF 452

  Fly   395 VFNLSQLVNMMSIGTLLAYSMVASCVLMLRYEVDDRRESRIVANGRATGLEQDRPCALWR----R 455
            :|:|..||::|||||||||::||.|||:|||:     .||:.::|...     :|..|.|    .
Zfish   453 LFDLDALVDLMSIGTLLAYTLVAVCVLILRYQ-----PSRLGSSGADV-----KPVELQRLEAKA 507

  Fly   456 IFNLNG--------QTVPTK-----------------QTSRIVTYSV-----TLFSLWCMVFSQI 490
            :.:::.        :|:|.|                 :.|.|:.||.     .||:|.|:|.|..
Zfish   508 VMDVDSGDEYSQDMETIPLKKRFSIRMLVQPICDVPTKISGIIVYSACGTISVLFTLLCLVLSVC 572

  Fly   491 LTKFEEDLANVTSFDGIKLVLGTIPLAVLLLVISRQPTSGVKLSFKVPLVPWLPGISILINIYLM 555
            |    |.:|.........:||.::...|.::||.|||.|...|:|||||:|.||.|||.:|||||
Zfish   573 L----EQVAMGHPLFICLVVLLSVLSTVCIVVIWRQPQSKEALTFKVPLLPILPLISIFVNIYLM 633

  Fly   556 IKLDILTWIRFSIWIAIGLAIFLAYGIRHSRLRQREQRNNS 596
            :::...|||||::|:|||..|:.|||||||    .|.:|||
Zfish   634 MQMSGATWIRFAVWMAIGFLIYFAYGIRHS----SEGKNNS 670

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5535	NP_649019.2	2A0303	20..585	CDD:273330	274/613 (45%)
slc7a3b	XP_001342962.3	2A0303	57..665	CDD:273330	276/619 (45%)