DRSC/TRiP Functional Genomics Resources

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Protein Alignment TrpRS-m and Wars2

DIOPT Version :9

Sequence 1:NP_001262001.1 Gene:TrpRS-m / 39989 FlyBaseID:FBgn0036763 Length:665 Species:Drosophila melanogaster
Sequence 2:NP_081738.2 Gene:Wars2 / 70560 MGIID:1917810 Length:360 Species:Mus musculus


Alignment Length:386 Identity:181/386 - (46%)
Similarity:246/386 - (63%) Gaps:29/386 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly    21 AVYSQRRCIQARSFLPGLASRTAGTPSATAQVTGGNKQHVHPHGNSVNSGHEEHNTRWPRKVFSG 85
            |::|.|:..:...|:..|....|.|.:...:                 ||         .:||||
Mouse     2 ALFSVRKARECWRFIRALHKGPAATLAPQKE-----------------SG---------ERVFSG 40

  Fly    86 IQPTGSLHLGNYLGAVRKWVQLQNARDDVTVCIVDLHSITMPHNPPLLRENIFTMAATLLACGID 150
            |||||.|||||||||:..||.||...|.|...||||||||:|.:|.:|:::|..|.|.||||||:
Mouse    41 IQPTGILHLGNYLGAIESWVNLQEEYDTVIYSIVDLHSITVPQDPTVLQQSILDMTAVLLACGIN 105

  Fly   151 PTKSTLFVQSAVAEHAEFNWILSSLTTMPRLAQLPQFREKSRLLK-DVPLGLYVYPVLQAADIML 214
            |.||.||.||.|:||.:.:|||:.:..:|||..|.|::.|:...| |..:||..|||||||||:.
Mouse   106 PEKSILFQQSKVSEHTQLSWILTCMVRLPRLQHLHQWKAKAAKQKHDGTVGLLTYPVLQAADILC 170

  Fly   215 YKSTHVPVGADQIQHIQLAQHLARIYNGRYGETFPVCTAIIEDGDASRVLSLRDPSKKMSKSEAN 279
            |||||||||.||:||::|.|.|||.:|.:|||.||:..:|:.  ...:|.||||||.|||||:.:
Mouse   171 YKSTHVPVGEDQVQHMELVQDLARSFNQKYGEFFPLPKSILT--SMKKVKSLRDPSSKMSKSDPD 233

  Fly   280 PKATINLCDSPDLITQKIKKAVTDFTSDITYNPGKRAGVSNLVNIHAQVTGQSIKTVVNEAATLD 344
            ..||:.:.|||:.|.||.:||||||||::||.|..||||||:|.|||.|:|.|::.||..:|.||
Mouse   234 KLATVRITDSPEEIVQKFRKAVTDFTSEVTYEPDSRAGVSNMVAIHAAVSGLSVEEVVRSSAGLD 298

  Fly   345 TAKYKDRVAEAVVEHLRPIREQIHHHMTKRNEMIYLLEVGAEKARQQARQTLNDVKQRLGL 405
            ||:||..||:||:|...|||::|......::.:..:|.||:.||::.|.....:||:.:|:
Mouse   299 TARYKLLVADAVIEKFAPIRKEIEKLKMDKDHLRKVLLVGSAKAKELASPVFEEVKKLVGI 359

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TrpRS-mNP_001262001.1 PRK00927 82..406 CDD:234866 172/325 (53%)
TrpRS_core 82..359 CDD:173903 158/277 (57%)
Wars2NP_081738.2 PRK00927 35..360 CDD:234866 172/327 (53%)
TrpRS_core 36..312 CDD:173903 158/277 (57%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167838138
Domainoid 1 1.000 312 1.000 Domainoid score I1314
eggNOG 1 0.900 - - E1_COG0180
Hieranoid 00.000 Not matched by this tool.
Homologene 1 1.000 - - H5673
Inparanoid 00.000 Not matched by this tool.
Isobase 1 0.950 - 0 Normalized mean entropy S1214
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0003309
OrthoInspector 1 1.000 - - oto91867
orthoMCL 1 0.900 - - OOG6_101334
Panther 1 1.100 - - LDO PTHR43766
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R1460
SonicParanoid 1 1.000 - - X2207
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
1312.680

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