Protein Alignment TrpRS-m and WARS2

DIOPT Version :10

• Sequence 1: NP_649018.2
• Gene: TrpRS-m / 39989
• FlyBaseID: FBgn0036763
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_056651.1
• Gene: WARS2 / 10352
• HGNCID: 12730
• Length: 360
• Species: Homo sapiens
• Alignment Length: 385
• Identity: 179/385 - (46%)
• Similarity: 253/385 - (65%)
• Gaps: 29/385 - (7%)

  Fly    21 AVYSQRRCIQARSFLPGLASRTAGTPSATAQVTGGNKQHVHPHGNSVNSGHEEHNTRWPRKVFSG 85
            |::|.|:..:..||:..|...:|..|:.                        :.:::  ::||||
Human     2 ALHSMRKARERWSFIRALHKGSAAAPAL------------------------QKDSK--KRVFSG 40

  Fly    86 IQPTGSLHLGNYLGAVRKWVQLQNARDDVTVCIVDLHSITMPHNPPLLRENIFTMAATLLACGID 150
            |||||.|||||||||:..||:||:..|.|...||||||||:|.:|.:||::|..|.|.||||||:
Human    41 IQPTGILHLGNYLGAIESWVRLQDEYDSVLYSIVDLHSITVPQDPAVLRQSILDMTAVLLACGIN 105

  Fly   151 PTKSTLFVQSAVAEHAEFNWILSSLTTMPRLAQLPQFREKSRLLK-DVPLGLYVYPVLQAADIML 214
            |.||.||.||.|:||.:.:||||.:..:|||..|.|::.|:...| |..:||..|||||||||:|
Human   106 PEKSILFQQSQVSEHTQLSWILSCMVRLPRLQHLHQWKAKTTKQKHDGTVGLLTYPVLQAADILL 170

  Fly   215 YKSTHVPVGADQIQHIQLAQHLARIYNGRYGETFPVCTAIIEDGDASRVLSLRDPSKKMSKSEAN 279
            |||||||||.||:||::|.|.||:.:|.:|||.|||..:|:.  ...:|.||||||.|||||:.:
Human   171 YKSTHVPVGEDQVQHMELVQDLAQGFNKKYGEFFPVPESILT--SMKKVKSLRDPSAKMSKSDPD 233

  Fly   280 PKATINLCDSPDLITQKIKKAVTDFTSDITYNPGKRAGVSNLVNIHAQVTGQSIKTVVNEAATLD 344
            ..||:.:.|||:.|.||.:||||||||::||:|..||||||:|.:||.|||.|::.||..:|.::
Human   234 KLATVRITDSPEEIVQKFRKAVTDFTSEVTYDPAGRAGVSNIVAVHAAVTGLSVEEVVRRSAGMN 298

  Fly   345 TAKYKDRVAEAVVEHLRPIREQIHHHMTKRNEMIYLLEVGAEKARQQARQTLNDVKQRLG 404
            ||:||..||:||:|...||:.:|......::.:..:|::|:.||::.|.....:||:.:|
Human   299 TARYKLAVADAVIEKFAPIKREIEKLKLDKDHLEKVLQIGSAKAKELAYTVCQEVKKLVG 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TrpRS-m	NP_649018.2	PRK00927	82..406	CDD:234866	171/324 (53%)
WARS2	NP_056651.1	PRK00927	34..360	CDD:234866	171/329 (52%)