DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7430 and GR

DIOPT Version :9

Sequence 1:	NP_001262000.1	Gene:	CG7430 / 39988	FlyBaseID:	FBgn0036762	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_191026.1	Gene:	GR / 824631	AraportID:	AT3G54660	Length:	565	Species:	Arabidopsis thaliana

Alignment Length:	517	Identity:	144/517 - (27%)
Similarity:	228/517 - (44%)	Gaps:	80/517 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 LRTNAAILGALNARCYSST-----------------HEADIVVIGSGPGG---------YVAAIK 55
            ||...|:|.  |.|.|.|.                 ::.|:..||:|.||         :.|:..
plant    52 LRPRIALLS--NHRYYHSRRFSVCASTDNGAESDRHYDFDLFTIGAGSGGVRASRFATSFGASAA 114

  Fly    56 AAQMGMKTVSVEKEATLGGTCLNVGCIPSKALLNNSHYYHMAHSGDLEKRGISC---GSVSLDLE 117
            ..::...|:|.:....:||||:..||:|.|.|:..|.|.|...    :..|...   ...|.|..
plant   115 VCELPFSTISSDTAGGVGGTCVLRGCVPKKLLVYASKYSHEFE----DSHGFGWKYETEPSHDWT 175

  Fly   118 KLMGQKSNAVKALTGGIAMLFKKNKVTQLTGFGTIVNPNEVEVKKSDGSTETVKTKNILIATGSE 182
            .|:..|:..::.|||....:..|..|..:.|.|.:::|:.|:|   ||...|  |:|||||.|..
plant   176 TLIANKNAELQRLTGIYKNILSKANVKLIEGRGKVIDPHTVDV---DGKIYT--TRNILIAVGGR 235

  Fly   183 VTPF----PGIEIDEEVIVSSTGALKLAKVPKHLVVIGAGVIGLELGSVWSRLGAEVTAIEFMDT 243
              ||    ||    :|..:.|..||.|...||.:.::|.|.|.||...:::.|..||........
plant   236 --PFIPDIPG----KEFAIDSDAALDLPSKPKKIAIVGGGYIALEFAGIFNGLNCEVHVFIRQKK 294

  Fly   244 IGGVGIDNEVSKTFQKVLTKQGLKFKLGTKVTAASRSGDNVTVSVENAKSGEKEEIQCDALLVSV 308
            :.. |.|.:|.....:.::.:|::|.......|..::||. :.|::.:| |..|..  ..::.:.
plant   295 VLR-GFDEDVRDFVGEQMSLRGIEFHTEESPEAIIKAGDG-SFSLKTSK-GTVEGF--SHVMFAT 354

  Fly   309 GRRPYTEGLGLEAVGIVKDDRGRIPVNATFQTVVPNIYAIGDCIHGPMLAHKAEDEGLITIEGIN 373
            ||:|.|:.||||.||:.....|.|.|:...||.||:|:|:||.         .:...|..:..:.
plant   355 GRKPNTKNLGLENVGVKMAKNGAIEVDEYSQTSVPSIWAVGDV---------TDRINLTPVALME 410

  Fly   374 GGHV----------HIDYNCVPSVVYTHPEVAWVGKSEEQ-LKQEG-VAYKVGKFPFLANSRAKT 426
            ||.:          ..||..||..|::.|.:..||.:||| ::|.| |......|..|   :|..
plant   411 GGALAKTLFQNEPTKPDYRAVPCAVFSQPPIGTVGLTEEQAIEQYGDVDVYTSNFRPL---KATL 472

  Fly   427 NNDTDG-FVKVLADQATDKILGTHIIGPGAGELINEAVLAMEYGAAAEDVARVCHAHPTCSE 487
            :...|. |:|::....|:|:||.|:.|..:.|:|....:|::.|....|.......|||.:|
plant   473 SGLPDRVFMKLIVCANTNKVLGVHMCGEDSPEIIQGFGVAVKAGLTKADFDATVGVHPTAAE 534

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7430	NP_001262000.1	PRK06327	35..504	CDD:235779	136/499 (27%)
		NADB_Rossmann	35..>74	CDD:304358	9/64 (14%)
		Pyr_redox	211..290	CDD:278498	17/78 (22%)
		Pyr_redox_dim	385..491	CDD:280934	32/106 (30%)
GR	NP_191026.1	PLN02546	1..565	CDD:215301	144/517 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1249
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D581771at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820