DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7430 and mtLPD2

DIOPT Version :9

Sequence 1:	NP_001262000.1	Gene:	CG7430 / 39988	FlyBaseID:	FBgn0036762	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_566570.3	Gene:	mtLPD2 / 820984	AraportID:	AT3G17240	Length:	507	Species:	Arabidopsis thaliana

Alignment Length:	472	Identity:	272/472 - (57%)
Similarity:	341/472 - (72%)	Gaps:	5/472 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 SSTHEADIVVIGSGPGGYVAAIKAAQMGMKTVSVEKEATLGGTCLNVGCIPSKALLNNSHYYHMA 97
            |.:.:.|:|:||.|||||||||||||:|:||..:||...|||||||||||||||||::||.||.|
plant    39 SGSDDNDVVIIGGGPGGYVAAIKAAQLGLKTTCIEKRGALGGTCLNVGCIPSKALLHSSHMYHEA 103

  Fly    98 -HSGDLEKRGISCGSVSLDLEKLMGQKSNAVKALTGGIAMLFKKNKVTQLTGFGTIVNPNEVEVK 161
             |.  ....|:...||.:||..::.||..|||.||.|:..|||||||..:.|:|..::|:||.|.
plant   104 KHV--FANHGVKVSSVEVDLPAMLAQKDTAVKNLTRGVEGLFKKNKVNYVKGYGKFLSPSEVSVD 166

  Fly   162 KSDGSTETVKTKNILIATGSEVTPFPGIEIDEEVIVSSTGALKLAKVPKHLVVIGAGVIGLELGS 226
            ..||....||.|:|::||||:|...|||.|||:.||||||||.|.::||.|:|||||.||||:||
plant   167 TIDGENVVVKGKHIIVATGSDVKSLPGITIDEKKIVSSTGALSLTEIPKKLIVIGAGYIGLEMGS 231

  Fly   227 VWSRLGAEVTAIEFMDTIGGVGIDNEVSKTFQKVLTKQGLKFKLGTKVTAASRSGDNVTVSVENA 291
            ||.|||:|||.:||...| ...:|.|:.|.||:.|.||.:||.|.|||.....|||.|.:.||.|
plant   232 VWGRLGSEVTVVEFAADI-VPAMDGEIRKQFQRSLEKQKMKFMLKTKVVGVDSSGDGVKLIVEPA 295

  Fly   292 KSGEKEEIQCDALLVSVGRRPYTEGLGLEAVGIVKDDRGRIPVNATFQTVVPNIYAIGDCIHGPM 356
            :.||:..::.|.:|||.||.|:|.||.||.:|:..|..|||.||..|.|.|..:|||||.|.|||
plant   296 EGGEQTTLEADVVLVSAGRTPFTSGLDLEKIGVETDKGGRILVNERFSTNVSGVYAIGDVIPGPM 360

  Fly   357 LAHKAEDEGLITIEGINGGHVHIDYNCVPSVVYTHPEVAWVGKSEEQLKQEGVAYKVGKFPFLAN 421
            ||||||::|:..:|.|.|.|.|:||:.||.||||:||||.|||:|||||:|||:|.||||||:||
plant   361 LAHKAEEDGVACVEFIAGKHGHVDYDKVPGVVYTYPEVASVGKTEEQLKKEGVSYNVGKFPFMAN 425

  Fly   422 SRAKTNNDTDGFVKVLADQATDKILGTHIIGPGAGELINEAVLAMEYGAAAEDVARVCHAHPTCS 486
            ||||..:..:|.||:|||:.||||||.||:.|.|||||:|||||:.|.|::||:|||||||||.|
plant   426 SRAKAIDTAEGMVKILADKETDKILGVHIMSPNAGELIHEAVLAINYDASSEDIARVCHAHPTMS 490

  Fly   487 EALREANVAAAFGKPIN 503
            ||::|| ..|.:.|||:
plant   491 EAIKEA-AMATYDKPIH 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7430	NP_001262000.1	PRK06327	35..504	CDD:235779	271/470 (58%)
		NADB_Rossmann	35..>74	CDD:304358	23/38 (61%)
		Pyr_redox	211..290	CDD:278498	42/78 (54%)
		Pyr_redox_dim	385..491	CDD:280934	74/105 (70%)
mtLPD2	NP_566570.3	Pyr_redox_2	41..507	CDD:423044	271/470 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	361	1.000	Domainoid score	I193
eggNOG	1	0.900	-	-		E1_COG1249
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H84
Inparanoid	1	1.050	545	1.000	Inparanoid score	I261
OMA	1	1.010	-	-		QHG60979
OrthoDB	1	1.010	-	-		D581771at2759
OrthoFinder	1	1.000	-	-		FOG0003111
OrthoInspector	1	1.000	-	-		otm3505
orthoMCL	1	0.900	-	-		OOG6_100523
Panther	1	1.100	-	-	O	PTHR22912
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2083
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.930