DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7430 and CG10700

DIOPT Version :9

Sequence 1:	NP_001262000.1	Gene:	CG7430 / 39988	FlyBaseID:	FBgn0036762	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_609942.1	Gene:	CG10700 / 35183	FlyBaseID:	FBgn0032754	Length:	539	Species:	Drosophila melanogaster

Alignment Length:	410	Identity:	82/410 - (20%)
Similarity:	144/410 - (35%)	Gaps:	112/410 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 CYSSTHEADIVVIGSGPGGYVAAIKAAQMGMKTVSVEKEATLGGTCLNVGCIPSKALLNNSHYYH 95
            |.:...:...||:|.||.|.|                             |:.:
  Fly   125 CRNWQDQRHFVVVGGGPSGAV-----------------------------CVET----------- 149

  Fly    96 MAHSGDLEKRGISCGSVSL--DLEKLMGQKSNAVKALTGGIAM----LFKKNKVTQLTGFGTIVN 154
            :...|...:..:.||...|  |..::|    |.:...|..:|:    .:|...:....|
  Fly   150 LRQEGFTGRLTLVCGEKHLPYDRTRIM----NLLNTYTKNLALREEQFYKDYGIEMQLG------ 204

  Fly   155 PNEVEVKKSDGSTETVKTKN--------ILIATG-SEVTP-FPGIEIDEEVIVSSTG----ALKL 205
               |..::.|.:..|:...|        |.|||| |.||| .||:.:....::.:.|    ..|:
  Fly   205 ---VSAERLDTNCNTLHCTNGKTFPYDKIYIATGYSAVTPNIPGVHLKNVKVIRNIGDARSIFKM 266

  Fly   206 AKVPKHLVVIGAGVIGLELGSVWSRLGAEVTA-----IEFMDTIGGVGIDNEVSKTFQKVLTKQG 265
            ......:|.:|:..:.:|..:........||.     :.|..|:|.: |...:.|..::  .|..
  Fly   267 VDKSTQVVCLGSSFMAVEATANLVSRARSVTLVARQNVPFKSTLGEL-IGQRILKLLEE--NKVD 328

  Fly   266 LKFKLGTKVTAASRSGDNVTVS-VENAKSGEKEEIQCDALLVSVGRRPYTEGLGLEAVGIVKDDR 329
            |:...|......:..|:.|.|. ::|::      |.|:.|::..|.:..|:  .|:..||..:..
  Fly   329 LRMSSGIIRILGNSRGEVVAVKLLDNSR------IPCNLLILGTGCQCNTD--FLQRSGININPN 385

  Fly   330 GRIPVNATFQTVVPNIYAIGDCIHGPMLAHKAEDEGLITIEGINGG---HVHIDYNCVPSVVYTH 391
            |.:.||...||.|.|:|..||..:..:|                ||   .|:|.:.   .:...|
  Fly   386 GSVDVNDFLQTKVRNVYVGGDIANAYIL----------------GGFPDRVNISHY---GLAQYH 431

  Fly   392 PEVAWVGKSEEQLKQEGVAY 411
            ..:|.:..|....|.|.:.:
  Fly   432 GRIAALNMSGHIAKLEAIPF 451

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7430	NP_001262000.1	PRK06327	35..504	CDD:235779	81/406 (20%)
		NADB_Rossmann	35..>74	CDD:304358	7/38 (18%)
		Pyr_redox	211..290	CDD:278498	16/84 (19%)
		Pyr_redox_dim	385..491	CDD:280934	5/27 (19%)
CG10700	NP_609942.1	Rieske_AIFL_N	10..106	CDD:239560
		Pyr_redox_2	135..414	CDD:285266	72/358 (20%)
		Pyr_redox	273..350	CDD:278498	15/79 (19%)
		COG3393	336..>508	CDD:225928	32/143 (22%)
		Reductase_C	464..527	CDD:291425
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464307
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840