DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7430 and CG4199

DIOPT Version :9

Sequence 1:	NP_001262000.1	Gene:	CG7430 / 39988	FlyBaseID:	FBgn0036762	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_001188537.1	Gene:	CG4199 / 31174	FlyBaseID:	FBgn0025628	Length:	593	Species:	Drosophila melanogaster

Alignment Length:	392	Identity:	87/392 - (22%)
Similarity:	144/392 - (36%)	Gaps:	96/392 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 VVIGSGPGGYVAAIKAAQMGM--KTVSVEKEATLGGTCLNVGCIPSKALLNNSHYYHMAHSGDLE 103
            :|:|.||.|.||.....|.|.  :.:.|.:|..|....:.:    |||:
  Fly   183 IVVGGGPSGAVAVETIRQEGFTGRLIFVCREDYLPYDRVKI----SKAM---------------- 227

  Fly   104 KRGISCGSVSLDLEKLMGQKSNAVK----ALTGGIAMLFKKNKVTQLTGFGTIVNPNEVEVKKSD 164
                     :|::|:|..:.....|    .|..|:|              ...::..:.|:..|:
  Fly   228 ---------NLEIEQLRFRDEEFYKEYDIELWQGVA--------------AEKLDTAQKELHCSN 269

  Fly   165 GSTETVKTKNILIATGSEV--TPFPGIEIDEEVIV---SSTGALKLAKVPKHLVVIGAGVIGLEL 224
            |  ..||...|.:|||...  .|.||:.::....|   :.|.|:..:..|:..||.        |
  Fly   270 G--YVVKYDKIYLATGCSAFRPPIPGVNLENVRTVRELADTKAILASITPESRVVC--------L 324

  Fly   225 GSVWSRLGAEVTAIEFMDTIGGVGIDN-EVSKTFQKVLTKQGLKFKLGTKVTAASRSGDNVTVSV 288
            ||.:..|.|....:..:.::..||.:| .:...|...:.::.|:.....||.....||....|..
  Fly   325 GSSFIALEAAAGLVSKVQSVTVVGRENVPLKAAFGAEIGQRVLQLFEDNKVVMRMESGIAEIVGN 389

  Fly   289 ENAKSGE-----KEEIQCDALLVSVGRRPYTEGLGLEAVGIVKDDRGRIPVNATFQTVVPNIYAI 348
            |:.|..|     ...:.||.|::..|.:..|:.|....|.:.::  |.:.|....::.||::|..
  Fly   390 EDGKVSEVVLVDDTRLPCDLLILGTGSKLNTQFLAKSGVKVNRN--GSVDVTDFLESNVPDVYVG 452

  Fly   349 GDC----IHGPMLAHKAEDEGLITIEGINGGHVHIDYNCVPSVVYTHPEVAWVGKSEEQLKQEGV 409
            ||.    |||  |||          :.:|.||..:        ...|..||.:.......|.|.|
  Fly   453 GDIANAHIHG--LAH----------DRVNIGHYQL--------AQYHGRVAAINMCGGVKKLEAV 497

  Fly   410 AY 411
            .:
  Fly   498 PF 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7430	NP_001262000.1	PRK06327	35..504	CDD:235779	87/392 (22%)
		NADB_Rossmann	35..>74	CDD:304358	12/34 (35%)
		Pyr_redox	211..290	CDD:278498	17/79 (22%)
		Pyr_redox_dim	385..491	CDD:280934	6/27 (22%)
CG4199	NP_001188537.1	Rieske_AIFL_N	59..154	CDD:239560
		Pyr_redox_2	183..465	CDD:285266	76/338 (22%)
		Pyr_redox	320..402	CDD:278498	20/89 (22%)
		Reductase_C	505..577	CDD:291425
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464306
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840