Protein Alignment CG7430 and GSR

DIOPT Version :9

• Sequence 1: NP_001262000.1
• Gene: CG7430 / 39988
• FlyBaseID: FBgn0036762
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_000628.2
• Gene: GSR / 2936
• HGNCID: 4623
• Length: 522
• Species: Homo sapiens
• Alignment Length: 480
• Identity: 139/480 - (28%)
• Similarity: 221/480 - (46%)
• Gaps: 56/480 - (11%)

  Fly    39 DIVVIGSGPGGYVAAIKAAQMGMKTVSVEKEATLGGTCLNVGCIPSKALLNNSHYYHMAHSGDLE 103
            |.:|||.|.||..:|.:||::|.:...||.. .|||||:||||:|.|.:.|.:.:....|  |..
Human    66 DYLVIGGGSGGLASARRAAELGARAAVVESH-KLGGTCVNVGCVPKKVMWNTAVHSEFMH--DHA 127

  Fly   104 KRGI-SC-GSVSLDLEKLMGQKSNA-VKALTGGIAMLFKKNKVTQLTGFGTIVNPNEVEVKKSDG 165
            ..|. || |..:.   :::.:|.:| |..|.........|:.:..:.|.....:..:..::.| |
Human   128 DYGFPSCEGKFNW---RVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDPKPTIEVS-G 188

  Fly   166 STETVKTKNILIATGS-EVTP----FPGIEIDEEVIVSSTGALKLAKVPKHLVVIGAGVIGLELG 225
            ...|  ..:||||||. ..||    .||..:.    ::|.|..:|.::|...|::|||.|.:|:.
Human   189 KKYT--APHILIATGGMPSTPHESQIPGASLG----ITSDGFFQLEELPGRSVIVGAGYIAVEMA 247

  Fly   226 SVWSRLGAEVTAIEFMDTIGGVGIDNEVSKTFQKVLTKQGLKFKLGTKVTAASRSGDNVTVSVEN 290
            .:.|.||::.:.:...|.:.. ..|:.:|....:.|...|::....::|....::...:.||:..
Human   248 GILSALGSKTSLMIRHDKVLR-SFDSMISTNCTEELENAGVEVLKFSQVKEVKKTLSGLEVSMVT 311

  Fly   291 AKSGEKEEI----QCDALLVSVGRRPYTEGLGLEAVGIVKDDRGRIPVNATFQTVVPNIYAIGD- 350
            |..|....:    ..|.||.::||.|.|:.|.|..:||..||:|.|.|:....|.|..|||:||
Human   312 AVPGRLPVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDDKGHIIVDEFQNTNVKGIYAVGDV 376

  Fly   351 C----------IHGPMLAHK----AEDEGLITIEGINGGHVHIDYNCVPSVVYTHPEVAWVGKSE 401
            |          ..|..|||:    .||..|             |||.:|:||::||.:..||.:|
Human   377 CGKALLTPVAIAAGRKLAHRLFEYKEDSKL-------------DYNNIPTVVFSHPPIGTVGLTE 428

  Fly   402 -EQLKQEGVA-YKVGKFPFLANSRAKTNNDTDGFVKVLADQATDKILGTHIIGPGAGELINEAVL 464
             |.:.:.|:. .|.....|.....|.|...|...:|::.....:|::|.|:.|.|..|::....:
Human   429 DEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKVVGIHMQGLGCDEMLQGFAV 493

  Fly   465 AMEYGAAAEDVARVCHAHPTCSEAL 489
            |::.||...|.......|||.||.|
Human   494 AVKMGATKADFDNTVAIHPTSSEEL 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7430	NP_001262000.1	PRK06327	35..504	CDD:235779	139/480 (29%)
		NADB_Rossmann	35..>74	CDD:304358	14/34 (41%)
		Pyr_redox	211..290	CDD:278498	17/78 (22%)
		Pyr_redox_dim	385..491	CDD:280934	32/107 (30%)
GSR	NP_000628.2	gluta_reduc_1	63..522	CDD:273614	139/480 (29%)
		Pyr_redox	233..307	CDD:278498	15/74 (20%)
		Pyr_redox_dim	412..520	CDD:280934	32/107 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1249
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D581771at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820