Protein Alignment CG7430 and Txnrd2

DIOPT Version :10

• Sequence 1: NP_649017.1
• Gene: CG7430 / 39988
• FlyBaseID: FBgn0036762
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_038739.2
• Gene: Txnrd2 / 26462
• MGIID: 1347023
• Length: 527
• Species: Mus musculus
• Alignment Length: 518
• Identity: 146/518 - (28%)
• Similarity: 231/518 - (44%)
• Gaps: 58/518 - (11%)

  Fly    18 RTNAAILGALNARCYSSTHEA-DIVVIGSGPGGYVAAIKAAQMGMKT-----VSVEKEAT---LG 73
            ||.|...|...|...:...:: |::|||.|.||...|.:|||:|.|.     |......|   ||
Mouse    22 RTRALTRGTRGAASAAGGQQSFDLLVIGGGSGGLACAKEAAQLGKKVAVADYVEPSPRGTKWGLG 86

  Fly    74 GTCLNVGCIPSK---------ALLNNSHYYHMAHSGDLEKRGISCGSVSLDLEKLMGQK-SNAVK 128
            |||:||||||.|         .::.::|:|....:..::...           |.|.:. .|.||
Mouse    87 GTCVNVGCIPKKLMHQAALLGGMIRDAHHYGWEVAQPVQHNW-----------KTMAEAVQNHVK 140

  Fly   129 ALTGGIAMLFKKNKVTQLTGFGTIVNPNEVEVKKSDGSTETVKTKNILIATGSEVTPFPGIEIDE 193
            :|..|..:..:..||.......:.|:.:.|......|....:..::|:||||........::...
Mouse   141 SLNWGHRVQLQDRKVKYFNIKASFVDEHTVRGVDKGGKATLLSAEHIVIATGGRPRYPTQVKGAL 205

  Fly   194 EVIVSSTGALKLAKVPKHLVVIGAGVIGLELGSVWSRLGAEVTAIEFMDTIGGVGIDNEVSKTFQ 258
            |..::|.....|.:.|...:|:||..:.||.....:.:|.:.|.:  |.:|...|.|.::|....
Mouse   206 EYGITSDDIFWLKESPGKTLVVGASYVALECAGFLTGIGLDTTVM--MRSIPLRGFDQQMSSLVT 268

  Fly   259 KVLTKQGLKFKLGTKVTAASRSGDN-VTVSVENAKSGEKEEIQCDALLVSVGRRPYTEGLGLEAV 322
            :.:...|.:|..|...:...:...| :.|:.|:..||:::....|.:|.::||.|.|..|.||..
Mouse   269 EHMESHGTQFLKGCVPSHIKKLPTNQLQVTWEDHASGKEDTGTFDTVLWAIGRVPETRTLNLEKA 333

  Fly   323 GIVKDDRG-RIPVNATFQTVVPNIYAIGDCIHG-PMLAHKAEDEGLITIEGING-GHVHIDYNCV 384
            ||..:.:. :|.|:|...|.||:||||||...| |.|...|...|.:..:.:.| ....:||:.|
Mouse   334 GISTNPKNQKIIVDAQEATSVPHIYAIGDVAEGRPELTPTAIKAGKLLAQRLFGKSSTLMDYSNV 398

  Fly   385 PSVVYTHPEVAWVGKSEEQL----KQEGVA-----YKVGKFPFLANSRAKTNNDTDG---FVK-V 436
            |:.|:|..|...||.|||:.    .||.|.     ||..:|         |..|.|.   ::| |
Mouse   399 PTTVFTPLEYGCVGLSEEEAVALHGQEHVEVYHAYYKPLEF---------TVADRDASQCYIKMV 454

  Fly   437 LADQATDKILGTHIIGPGAGELINEAVLAMEYGAAAEDVARVCHAHPTCSEALREANVAAAFG 499
            ...:....:||.|.:||.|||:.....|.::.||:...|.:....||||||.:.:.:::...|
Mouse   455 CMREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMQTVGIHPTCSEEVVKLHISKRSG 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7430	NP_649017.1	Pyr_redox_2	35..504	CDD:476868	141/501 (28%)
Txnrd2	NP_038739.2	TGR	43..527	CDD:273624	141/497 (28%)