DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5567 and pgp

DIOPT Version :9

Sequence 1:	NP_649015.2	Gene:	CG5567 / 39986	FlyBaseID:	FBgn0036760	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	NP_997891.2	Gene:	pgp / 792824	ZFINID:	ZDB-GENE-030131-6240	Length:	306	Species:	Danio rerio

Alignment Length:	307	Identity:	124/307 - (40%)
Similarity:	196/307 - (63%)	Gaps:	8/307 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 SCTNLLELSSAKVTEWLAGFDSVITDCDGVLWIYGQALEGSVDVMNQLKGMGKSIYFCTNNSTKT 84
            :.:..:.|:.|...:.|...|.|:.|||||:|...||:.|:.:|:|.||..||.::|.|||||||
Zfish     2 AASKCVRLNGALSRQLLDSVDCVLFDCDGVIWRGDQAIPGAPEVINSLKKHGKQVFFVTNNSTKT 66

  Fly    85 RSELLKKGVELGFHIKENGIISTAHATAAYLKRRNFSK---RVFVIGSEGITKELDAVGIQHTEV 146
            |.....|..:|||....:.:..||:.:|.|||  |..|   :|::|||:.:.:||:.||||...|
Zfish    67 RQMYADKLGKLGFDAAADEVFGTAYCSAQYLK--NVCKLDGKVYLIGSKAMKQELEEVGIQPVGV 129

  Fly   147 GPEPMKGSLAEFMAQHLKLDTDIGAVVVGFDEHFSFPKMMKAASYLNDPECLFVATNTDERFPMP 211
            ||:.:.|...::  .::.||.::.||:||||||||:.|:.:|..||.||:|.||.||||.|.|:.
Zfish   130 GPDLISGVQIDW--ANVPLDQEVQAVLVGFDEHFSYMKLNRALQYLCDPDCQFVGTNTDTRLPLE 192

  Fly   212 -NMIVPGSGSFVRAIQTCAERDPVVIGKPNPAICESLVTEKKIDPSRTLMIGDRANTDILLGFNC 275
             ...|||:|..:||::|.|:|...|:|||:..:.|.:.::..:.|.|.||:|||.:|||:||.||
Zfish   193 GGKAVPGTGCLLRAVETAAQRQAQVVGKPSNFMFECVASQFNLKPQRCLMVGDRLDTDIMLGSNC 257

  Fly   276 GFQTLLVGSGIHQLKDVERWKLSQDPEEKKLIPDVYLPKLGDLLPSI 322
            |.:|||..:|:..:.:.|..:.|:.|::::::||.|:..:.|:||::
Zfish   258 GLKTLLTLTGVSTVAEAEANQKSECPQKQRMVPDYYIESIADILPAL 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5567	NP_649015.2	PGP_euk	40..318	CDD:273635	118/281 (42%)
		Hydrolase_6	42..142	CDD:290083	45/102 (44%)
		Hydrolase_like	235..318	CDD:289983	30/82 (37%)
pgp	NP_997891.2	PGP_euk	21..300	CDD:273635	118/282 (42%)
		Hydrolase_6	24..125	CDD:290083	45/102 (44%)
		Hydrolase_like	217..299	CDD:289983	30/81 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583992
Domainoid	1	1.000	87	1.000	Domainoid score	I8001
eggNOG	1	0.900	-	-		E1_COG0647
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5513
Inparanoid	1	1.050	242	1.000	Inparanoid score	I3298
OMA	1	1.010	-	-		QHG60740
OrthoDB	1	1.010	-	-		D337140at33208
OrthoFinder	1	1.000	-	-		FOG0000783
OrthoInspector	1	1.000	-	-		otm26379
orthoMCL	1	0.900	-	-		OOG6_100677
Panther	1	1.100	-	-	LDO	PTHR19288
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R944
SonicParanoid	1	1.000	-	-		X675
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800