DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5567 and pdxp

DIOPT Version :9

Sequence 1:	NP_649015.2	Gene:	CG5567 / 39986	FlyBaseID:	FBgn0036760	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	NP_001122177.1	Gene:	pdxp / 561030	ZFINID:	ZDB-GENE-080723-69	Length:	308	Species:	Danio rerio

Alignment Length:	296	Identity:	117/296 - (39%)
Similarity:	174/296 - (58%)	Gaps:	7/296 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 LSSAKVTEWLAGFDSVITDCDGVLWIYGQALEGSVDVMNQLKGMGKSIYFCTNNSTKTRSELLKK 91
            |..|::.:.|....:|:.|||||:|....|:.|:.:|::.||..||.::|.|||.|:.|...::|
Zfish    11 LRGAQIRDLLDAKHNVLFDCDGVIWNGETAVAGAPEVVSLLKQRGKRVFFVTNNCTRPRENYVQK 75

  Fly    92 GVELGF-HIKENGIISTAHATAAYLKR-RNFSKRVFVIGSEGITKELDAVGIQHTEVGPEPMKGS 154
            ...||| .:.|..|.|:|:.:||||:. .....:|:.||..|:.|||...|:...|...|..:|:
Zfish    76 FSRLGFADVAEEEIFSSAYCSAAYLRDVARLQGKVYAIGGGGVLKELRDAGVPVVEEPAEQEEGT 140

  Fly   155 LAEFMAQHLKLDTDIGAVVVGFDEHFSFPKMMKAASYLNDPECLFVATNTDERFPM-PNMIVPGS 218
                ...:..||.|:.||:||:||.|:|.|:.||..||.|.||||:||:.|...|: ...|.|||
Zfish   141 ----SIYNCPLDPDVRAVLVGYDESFTFMKLAKACCYLRDAECLFLATDPDPWHPLRGGRITPGS 201

  Fly   219 GSFVRAIQTCAERDPVVIGKPNPAICESLVTEKKIDPSRTLMIGDRANTDILLGFNCGFQTLLVG 283
            ||...|::|.:.|...|||||:..:.:.:.::..:||||:||||||..||||.|.|||..|:|..
Zfish   202 GSLTAALETASSRKATVIGKPSRFMFDCISSQFDLDPSRSLMIGDRLETDILFGSNCGLSTVLTL 266

  Fly   284 SGIHQLKDVERWKLSQDPEEKKLIPDVYLPKLGDLL 319
            :|:..|.:.:|::.||.||:|...||..:..:.|.|
Zfish   267 TGVSTLDEAQRYRDSQSPEQKDCAPDFVVESVADFL 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5567	NP_649015.2	PGP_euk	40..318	CDD:273635	112/280 (40%)
		Hydrolase_6	42..142	CDD:290083	40/101 (40%)
		Hydrolase_like	235..318	CDD:289983	35/82 (43%)
pdxp	NP_001122177.1	PGP_euk	26..300	CDD:273635	112/277 (40%)
		Hydrolase_6	26..127	CDD:290083	39/100 (39%)
		Hydrolase_like	218..300	CDD:289983	35/81 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584003
Domainoid	1	1.000	62	1.000	Domainoid score	I10313
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	242	1.000	Inparanoid score	I3298
OMA	1	1.010	-	-		QHG60740
OrthoDB	1	1.010	-	-		D337140at33208
OrthoFinder	1	1.000	-	-		FOG0000783
OrthoInspector	1	1.000	-	-		otm26379
orthoMCL	1	0.900	-	-		OOG6_100677
Panther	1	1.100	-	-	O	PTHR19288
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R944
SonicParanoid	1	1.000	-	-		X675
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.940