Protein Alignment CG5567 and HDHD5

DIOPT Version :10

• Sequence 1: NP_649015.2
• Gene: CG5567 / 39986
• FlyBaseID: FBgn0036760
• Length: 330
• Species: Drosophila melanogaster
• Sequence 2: NP_149061.1
• Gene: HDHD5 / 27440
• HGNCID: 1843
• Length: 423
• Species: Homo sapiens
• Alignment Length: 295
• Identity: 61/295 - (20%)
• Similarity: 108/295 - (36%)
• Gaps: 65/295 - (22%)

  Fly    38 GFDSVITDCDGVLWIYGQ-----ALEGSVDVMNQLKGMGKSIYFCTN-NSTKTRSELLKKGVELG 96
            ||   :.|.|||| :.|.     ||:....::|....:...:.|.|| .:....|:..:....||
Human    48 GF---LLDIDGVL-VRGHRVIPAALKAFRRLVNSQGQLRVPVVFVTNAGNILQHSKAQELSALLG 108

  Fly    97 FHIKENGIISTAHATAAYLKRRNFSKRVFVIGSEGITKELDAVGIQHTEVGPE-PMKGSLAEFMA 160
            ..:..:.:| .:|:........: .||:.|.|...:.:....:|.::.....| .|...|.:.:.
Human   109 CEVDADQVI-LSHSPMKLFSEYH-EKRMLVSGQGPVMENAQGLGFRNVVTVDELRMAFPLLDMVD 171

  Fly   161 QHLKLDT------DI----GAVVVGFDEHFSFPKMMKAASYLND------------PECLFVATN 203
            ...:|.|      |.    |.:::|....:.....:.....|::            |....:|:|
Human   172 LERRLKTTPLPRNDFPRIEGVLLLGEPVRWETSLQLIMDVLLSNGSPGAGLATPPYPHLPVLASN 236

  Fly   204 TD----ERFPMPNMIVPGSGSFVRAIQTCAERDPVVIGKP--------NPAI-----CESLV--- 248
            .|    ....||..   |.|:|:..::|..::   |.||.        .|:|     .|.|:
Human   237 MDLLWMAEAKMPRF---GHGTFLLCLETIYQK---VTGKELRYEGLMGKPSILTYQYAEDLIRRQ 295

  Fly   249 TEKK--IDPSRTL-MIGDRANTDILLGFNCGFQTL 280
            .|::  ..|.|.| .:||...:|: .|.|...|.|
Human   296 AERRGWAAPIRKLYAVGDNPMSDV-YGANLFHQYL 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5567	NP_649015.2	HAD_PNPase_UmpH-like	34..318	CDD:319834	61/295 (21%)
HDHD5	NP_149061.1	CECR5	47..360	CDD:200106	61/295 (21%)