DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5567 and pgph-1

DIOPT Version :9

Sequence 1:	NP_649015.2	Gene:	CG5567 / 39986	FlyBaseID:	FBgn0036760	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	NP_504509.1	Gene:	pgph-1 / 178963	WormBaseID:	WBGene00019604	Length:	322	Species:	Caenorhabditis elegans

Alignment Length:	303	Identity:	124/303 - (40%)
Similarity:	185/303 - (61%)	Gaps:	22/303 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 AKVTEWLAGFDSVITDCDGVLWIYGQALEGSVDVMNQLKGMGKSIYFCTNNSTKTRSELLKKGVE 94
            |||.:.:   |:.|.|.|||||:....:.||..:::.|....|.|...|||:||:|:...||..:
Worm    23 AKVMKTI---DTFIFDADGVLWLGESVMPGSPRLIDYLVKHNKQIIVLTNNATKSRAVYAKKLAK 84

  Fly    95 LGFH---IKENGIISTAHATAAYLKRRNF-SKRVFVIGSEGITKELDAVGIQHTEVGPEPMK--- 152
            ||::   :.:|.:::.|...|..|.|... .|||::||.:|:..|:|.:||::...|||..:
Worm    85 LGYNSSKMNKNNLVNPAAVVADTLHRAGLDGKRVYLIGEQGLRDEMDELGIEYFGHGPEKKQDEA 149

  Fly   153 -GSLAEFMAQHLKLDTDIGAVVVGFDEHFSFPKMMKAASYLNDPECLFVATNTDERFPMPN--MI 214
             ||.| || ..:||:.::||||||:::||.:.|||||::||.:...||||||.||..|.||  ::
Worm   150 DGSGA-FM-YDIKLEENVGAVVVGYEKHFDYVKMMKASNYLREEGVLFVATNEDETCPGPNPEVV 212

  Fly   215 VPGSGSFVRAIQTCAERDPVVIGKP-NPAICESLVTEK-KIDPSRTLMIGDRANTDILLGFNCGF 277
            :|.:|..|.||:..:.|||:.:||| .||.  :.:..| .|:||||:|||||.|||:..|.:.|.
Worm   213 IPDAGPIVAAIKCASGRDPLTVGKPCTPAF--NYIKRKWNINPSRTMMIGDRTNTDVKFGRDHGM 275

  Fly   278 QTLLVGSGIHQLKDVERWKLSQDPEEKKLIPDVYLPKLGDLLP 320
            :||||.||.||::|:..   :|..|...::||...|.||.|:|
Worm   276 KTLLVLSGCHQIEDIIE---NQMNERDDMVPDYVAPCLGALVP 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5567	NP_649015.2	PGP_euk	40..318	CDD:273635	119/289 (41%)
		Hydrolase_6	42..142	CDD:290083	36/103 (35%)
		Hydrolase_like	235..318	CDD:289983	37/84 (44%)
pgph-1	NP_504509.1	PGP_euk	28..313	CDD:273635	119/294 (40%)
		Hydrolase_6	32..136	CDD:290083	36/103 (35%)
		Hydrolase_like	234..313	CDD:289983	37/83 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	77	1.000	Domainoid score	I5732
eggNOG	1	0.900	-	-		E1_COG0647
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5513
Inparanoid	1	1.050	204	1.000	Inparanoid score	I2439
Isobase	1	0.950	-	0	Normalized mean entropy	S1709
OMA	1	1.010	-	-		QHG60740
OrthoDB	1	1.010	-	-		D337140at33208
OrthoFinder	1	1.000	-	-		FOG0000783
OrthoInspector	1	1.000	-	-		mtm4753
orthoMCL	1	0.900	-	-		OOG6_100677
Panther	1	1.100	-	-	O	PTHR19288
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R944
SonicParanoid	1	1.000	-	-		X675
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.820