DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5567 and pgp

DIOPT Version :9

Sequence 1:	NP_649015.2	Gene:	CG5567 / 39986	FlyBaseID:	FBgn0036760	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	NP_001363850.1	Gene:	pgp / 100488448	XenbaseID:	XB-GENE-999283	Length:	306	Species:	Xenopus tropicalis

Alignment Length:	312	Identity:	128/312 - (41%)
Similarity:	193/312 - (61%)	Gaps:	16/312 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 MYKQSCTNLL-ELSSAKVTEWLAGFDSVITDCDGVLWIYGQALEGSVDVMNQLKGMGKSIYFCTN 79
            |....|:.|. |||    ..:||..|:|:.|||||||...:|:.|:.|::|.||...|.::|.||
Frog     1 MAASKCSRLNGELS----RRFLASVDTVLFDCDGVLWRGDEAIPGAPDLINGLKRANKRVFFLTN 61

  Fly    80 NSTKTRSELLKKGVELGFHIKENGIISTAHATAAYLKRRNFSK---RVFVIGSEGITKELDAVGI 141
            |||||||...:|...|||..:...:..||:.||.||  |:.::   :|::||...:::|..|.||
Frog    62 NSTKTRSMYAEKLGRLGFKAEPEEVFGTAYCTAIYL--RDIARLKGKVYLIGGRALSEEFGAAGI 124

  Fly   142 QHTEVGPEPMKGSLAEFMAQHLKLDTDIGAVVVGFDEHFSFPKMMKAASYLNDPECLFVATNTDE 206
            .|...|.:.:.|:..::.:  ::.|:|:.|||||||||||:.|:.:|..||.||.|||:|||||.
Frog   125 PHLGCGADHVTGTQKDWAS--VQGDSDVKAVVVGFDEHFSYMKLNRALQYLQDPSCLFIATNTDT 187

  Fly   207 RFPMP-NMIVPGSGSFVRAIQTCAERDPVVIGKPNPAICESLVTEKKIDPSRTLMIGDRANTDIL 270
            |.|:. ...:||:|..|||::|.|.|...|||||:..:.:.:|.:..:||:||:|:|||.:|||.
Frog   188 RLPLEGGRAIPGTGCLVRAVETAAHRKAQVIGKPSSFLYDCVVKDCGLDPARTVMVGDRLDTDIQ 252

  Fly   271 LGFNCGFQTLLVGSGIHQLKDVERWKLSQDPEEKKLIPDVYLPKLGDLLPSI 322
            :|..||.:|||..:|...|:|.:.:   ||.....::||.|:..:.||||::
Frog   253 MGSTCGIRTLLTLTGFSSLEDAKSY---QDSGALSMVPDYYVNSVADLLPAL 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5567	NP_649015.2	PGP_euk	40..318	CDD:273635	116/281 (41%)
		Hydrolase_6	42..142	CDD:290083	42/102 (41%)
		Hydrolase_like	235..318	CDD:289983	31/82 (38%)
pgp	NP_001363850.1	HAD_like	21..301	CDD:389748	120/286 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	84	1.000	Domainoid score	I8177
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5513
Inparanoid	1	1.050	235	1.000	Inparanoid score	I3318
OMA	1	1.010	-	-		QHG60740
OrthoDB	1	1.010	-	-		D337140at33208
OrthoFinder	1	1.000	-	-		FOG0000783
OrthoInspector	1	1.000	-	-		otm48314
Panther	1	1.100	-	-	LDO	PTHR19288
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R944
SonicParanoid	1	1.000	-	-		X675
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110