DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5577 and PHO13

DIOPT Version :9

Sequence 1:	NP_001303369.1	Gene:	CG5577 / 39985	FlyBaseID:	FBgn0036759	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	NP_010045.1	Gene:	PHO13 / 851362	SGDID:	S000002395	Length:	312	Species:	Saccharomyces cerevisiae

Alignment Length:	318	Identity:	89/318 - (27%)
Similarity:	144/318 - (45%)	Gaps:	21/318 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 RGGAIDLTGLSEEQVSEWLQSFDTVLCDGDGTIWQDDTAIAGAPDVVNALQDRFDKKVYLITNNG 67
            :|..|.:|  ::|...|:|..:||.|.|.||.:|....|:....:::|.|: :..|::..:|||.
Yeast     5 QGVPIKIT--NKEIAQEFLDKYDTFLFDCDGVLWLGSQALPYTLEILNLLK-QLGKQLIFVTNNS 66

  Fly    68 LKTRQELFERSQRLGFHLPSDRHIISPTAA---IADYLVGSPKFDRTRHKVYVVGNAAIARELRQ 129
            .|:|....::....|..:..::...|..|:   |.|:|    |....:.||:|.|.:.|..||:.
Yeast    67 TKSRLAYTKKFASFGIDVKEEQIFTSGYASAVYIRDFL----KLQPGKDKVWVFGESGIGEELKL 127

  Fly   130 RGIDSYGAGGTDELPPGD--KWPDFVTREFGNPEAAKDVGAVVVGWDEYFSYCKMARACHILCSN 192
            .|.:|.|...:....|.|  |.|..|.      ...|||..|:.|.|...:|.::|.....| ..
Yeast   128 MGYESLGGADSRLDTPFDAAKSPFLVN------GLDKDVSCVIAGLDTKVNYHRLAVTLQYL-QK 185

  Fly   193 PDAAFLVTNRDAVHKYPSFCIPGTGAFVAGIEACSEREALEMGKPNPLVLEPFIKAEGLRTERTL 257
            ....|:.||.|:......:..||.|:.:..:...|.|.....||||..:|...|.|..|...:..
Yeast   186 DSVHFVGTNVDSTFPQKGYTFPGAGSMIESLAFSSNRRPSYCGKPNQNMLNSIISAFNLDRSKCC 250

  Fly   258 MIGDCLKIDVGFASNCGM-LSLLVGTGRYNNLSDVRLEKDRLPQPDFYLPRLGDLLNI 314
            |:||.|..|:.|....|: .:|||.:|.......:::..| .|:|.||:.:|||:..:
Yeast   251 MVGDRLNTDMKFGVEGGLGGTLLVLSGIETEERALKISHD-YPRPKFYIDKLGDIYTL 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5577	NP_001303369.1	PGP_euk	25..311	CDD:273635	82/291 (28%)
		Hydrolase_6	27..132	CDD:290083	28/107 (26%)
		Hydrolase_like	234..311	CDD:289983	26/77 (34%)
PHO13	NP_010045.1	HAD_Pase_UmpH-like	24..308	CDD:319813	83/297 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I2983
eggNOG	1	0.900	-	-		E1_COG0647
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	165	1.000	Inparanoid score	I1038
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60740
OrthoFinder	1	1.000	-	-		FOG0000783
OrthoInspector	1	1.000	-	-		otm46746
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.830