Protein Alignment CG5577 and Pgp

DIOPT Version :10

• Sequence 1: NP_649014.1
• Gene: CG5577 / 39985
• FlyBaseID: FBgn0036759
• Length: 315
• Species: Drosophila melanogaster
• Sequence 2: NP_080230.2
• Gene: Pgp / 67078
• MGIID: 1914328
• Length: 321
• Species: Mus musculus
• Alignment Length: 327
• Identity: 110/327 - (33%)
• Similarity: 162/327 - (49%)
• Gaps: 46/327 - (14%)

  Fly    12 LSEEQVSEWLQSFDTVLCDGDGTIWQDDTAIAGAPDVVNALQDRFDKKVYLITNNGLKTRQELFE 76
            ||.|:....|...||:|.|.||.:|:.:||:.|||:.:.||:.| .|::..||||..|||....|
Mouse    16 LSAERAKLLLAEVDTLLFDCDGVLWRGETAVPGAPETLRALRAR-GKRLGFITNNSSKTRTAYAE 79

  Fly    77 RSQRLGFHLPSDRHIISPTAAIADY-------------LVGSPKFDRTRHKVYVVGNAAIARELR 128
            :.:||||..|     :.|.|.:..:             |.|.|.     .|.||:|:.|:|.||.
Mouse    80 KLRRLGFGGP-----VGPEAGLEVFGTAYCSALYLRQRLAGVPD-----PKAYVLGSPALAAELE 134

  Fly   129 QRGIDSYGAGGTDELPPGDKWPDFVTREFGNPEAAKDVGAVVVGWDEYFSYCKMARACHILCSNP 193
            ..|:.|.|.|  .::..||...|::.     .....||.|||||:|.:|||.|:.:|...| ..|
Mouse   135 AVGVTSVGVG--PDVLHGDGPSDWLA-----VPLEPDVRAVVVGFDPHFSYMKLTKAVRYL-QQP 191

  Fly   194 DAAFLVTNRDAVHKYP---SFCIPGTGAFVAGIEACSEREALEMGKPNPLVLEPFIKAEGLRTER 255
            |...:.||.|  ::.|   ...|.|||..|..:|..::|:|..:|||:..:.:...:..|:..||
Mouse   192 DCLLVGTNMD--NRLPLENGRFIAGTGCLVRAVEMAAQRQADIIGKPSRFIFDCVSQEYGINPER 254

  Fly   256 TLMIGDCLKIDVGFASNCGMLSLLVGTG-------RYNNLSDVRLEKDRLPQPDFYLPRLGDLLN 313
            |:|:||.|..|:...|.|.:.::|..||       :.|..||...:|..:  ||||:..:.|||.
Mouse   255 TVMVGDRLDTDILLGSTCSLKTILTLTGVSSLEDVKSNQESDCMFKKKMV--PDFYVDSIADLLP 317

  Fly   314 IL 315
            .|
Mouse   318 AL 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5577	NP_649014.1	HAD_PNPase_UmpH-like	19..311	CDD:319834	103/314 (33%)
Pgp	NP_080230.2	HAD_Pase_UmpH-like	28..319	CDD:319813	105/313 (34%)