Protein Alignment CG5577 and PGP

DIOPT Version :10

• Sequence 1: NP_649014.1
• Gene: CG5577 / 39985
• FlyBaseID: FBgn0036759
• Length: 315
• Species: Drosophila melanogaster
• Sequence 2: NP_001035830.1
• Gene: PGP / 283871
• HGNCID: 8909
• Length: 321
• Species: Homo sapiens
• Alignment Length: 329
• Identity: 112/329 - (34%)
• Similarity: 166/329 - (50%)
• Gaps: 50/329 - (15%)

  Fly    12 LSEEQVSEWLQSFDTVLCDGDGTIWQDDTAIAGAPDVVNALQDRFDKKVYLITNNGLKTRQELFE 76
            ||.|:....|...||:|.|.||.:|:.:||:.|||:.:.||:.| .|::..||||..|||....|
Human    16 LSAERAQALLADVDTLLFDCDGVLWRGETAVPGAPEALRALRAR-GKRLGFITNNSSKTRAAYAE 79

  Fly    77 RSQRLGFHLPSDRHIISPTAAIADY-------------LVGSPKFDRTRHKVYVVGNAAIARELR 128
            :.:||||..|:     .|.|::..:             |.|:|     ..|.||:|:.|:|.||.
Human    80 KLRRLGFGGPA-----GPGASLEVFGTAYCTALYLRQRLAGAP-----APKAYVLGSPALAAELE 134

  Fly   129 QRGIDSYGAGGTDELP---PGDKWPDFVTREFGNPEAAKDVGAVVVGWDEYFSYCKMARACHILC 190
            ..|:.|.|. |.:.|.   ||| |.        :.....||.|||||:|.:|||.|:.:|...|
Human   135 AVGVASVGV-GPEPLQGEGPGD-WL--------HAPLEPDVRAVVVGFDPHFSYMKLTKALRYL- 188

  Fly   191 SNPDAAFLVTNRDAVHKYP---SFCIPGTGAFVAGIEACSEREALEMGKPNPLVLEPFIKAEGLR 252
            ..|....:.||.|  ::.|   ...|.|||..|..:|..::|:|..:|||:..:.:...:..|:.
Human   189 QQPGCLLVGTNMD--NRLPLENGRFIAGTGCLVRAVEMAAQRQADIIGKPSRFIFDCVSQEYGIN 251

  Fly   253 TERTLMIGDCLKIDVGFASNCGMLSLLVGTGRYNNLSDVR--LEKDRLPQ----PDFYLPRLGDL 311
            .|||:|:||.|..|:...:.||:.::|..|| .:.|.||:  .|.|.:.:    ||||:..:.||
Human   252 PERTVMVGDRLDTDILLGATCGLKTILTLTG-VSTLGDVKNNQESDCVSKKKMVPDFYVDSIADL 315

  Fly   312 LNIL 315
            |..|
Human   316 LPAL 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5577	NP_649014.1	HAD_PNPase_UmpH-like	19..311	CDD:319834	105/316 (33%)
PGP	NP_001035830.1	HAD_Pase_UmpH-like	28..319	CDD:319813	107/315 (34%)