Protein Alignment CG5577 and HDHD5

DIOPT Version :9

• Sequence 1: NP_001303369.1
• Gene: CG5577 / 39985
• FlyBaseID: FBgn0036759
• Length: 315
• Species: Drosophila melanogaster
• Sequence 2: NP_149061.1
• Gene: HDHD5 / 27440
• HGNCID: 1843
• Length: 423
• Species: Homo sapiens
• Alignment Length: 339
• Identity: 70/339 - (20%)
• Similarity: 109/339 - (32%)
• Gaps: 101/339 - (29%)

  Fly    28 LCDGDGTIWQDDTAIAGAPDVVNAL---QDRFDKKVYLITNNG-LKTRQELFERSQRLGFHLPSD 88
            |.|.||.:.:....|..|......|   |.:....|..:||.| :....:..|.|..||..:.:|
Human    50 LLDIDGVLVRGHRVIPAALKAFRRLVNSQGQLRVPVVFVTNAGNILQHSKAQELSALLGCEVDAD 114

  Fly    89 RHII--SPTAAIADYLVGSPKFDRTRHKVYVVGNAAIARELRQRGIDSYGAGGTDELPPGDKWPD 151
            :.|:  ||....::|         ...::.|.|...:..  ..:|:........|||.......|
Human   115 QVILSHSPMKLFSEY---------HEKRMLVSGQGPVME--NAQGLGFRNVVTVDELRMAFPLLD 168

  Fly   152 FV-------TREFGNPEAAKDVGAVVVG----WDEYFSYCKMARACHILCSN------------P 193
            .|       |......:..:..|.:::|    |:     ..:.....:|.||            |
Human   169 MVDLERRLKTTPLPRNDFPRIEGVLLLGEPVRWE-----TSLQLIMDVLLSNGSPGAGLATPPYP 228

  Fly   194 DAAFLVTNRD----AVHKYPSFCIPGTGAFVAGIEACSER--------EALEMGKPNPLV---LE 243
            ....|.:|.|    |..|.|.|   |.|.|:..:|...::        |.| ||||:.|.   .|
Human   229 HLPVLASNMDLLWMAEAKMPRF---GHGTFLLCLETIYQKVTGKELRYEGL-MGKPSILTYQYAE 289

  Fly   244 PFIKAEGLR------TERTLMIGDCLKIDVGFASNC----------------------------- 273
            ..|:.:..|      ..:...:||....|| :.:|.
Human   290 DLIRRQAERRGWAAPIRKLYAVGDNPMSDV-YGANLFHQYLQKATHDGAPELGAGGTRQQQPSAS 353

  Fly   274 -GMLSLLVGTGRYN 286
             ..:|:||.||.||
Human   354 QSCISILVCTGVYN 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5577	NP_001303369.1	PGP_euk	25..311	CDD:273635	70/339 (21%)
		Hydrolase_6	27..132	CDD:290083	23/109 (21%)
		Hydrolase_like	234..311	CDD:289983	20/92 (22%)
HDHD5	NP_149061.1	CECR5	47..360	CDD:200106	64/330 (19%)
		Hydrolase_6	49..152	CDD:290083	24/112 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0647
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900