DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5577 and pho2

DIOPT Version :9

Sequence 1:	NP_001303369.1	Gene:	CG5577 / 39985	FlyBaseID:	FBgn0036759	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	NP_596255.1	Gene:	pho2 / 2539960	PomBaseID:	SPBC15D4.15	Length:	298	Species:	Schizosaccharomyces pombe

Alignment Length:	308	Identity:	88/308 - (28%)
Similarity:	140/308 - (45%)	Gaps:	29/308 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 SEEQVSEWLQSFDTVLCDGDGTIWQDDTAIAGAPDVVNALQDRFDKKVYLITNNGLKTRQELFER 77
            |.::..|::..||..|.|.||.:|.....|.|..|.:..|:. ..|::..::||..|:|:....:
pombe     7 SPKEYKEFIDKFDVFLFDCDGVLWSGSKPIPGVTDTMKLLRS-LGKQIIFVSNNSTKSRETYMNK 70

  Fly    78 SQRLGFHLPSDRHIISPTA-AIADYLVGSPKFDRTRHKVYVVGNAAIARELRQRGIDSYGAGGTD 141
            ....|  :.:....|.|:| :.|.|:....|....: ||:|:|.|.|..||.:.|:..  .||||
pombe    71 INEHG--IAAKLEEIYPSAYSSATYVKKVLKLPADK-KVFVLGEAGIEDELDRVGVAH--IGGTD 130

  Fly   142 ELPPGDKWPDFVTREFGNPEAAK-----DVGAVVVGWDEYFSYCKMARACHILCSNPDAAFLVTN 201
                    |. :.|...:.:..|     .||||:.|.|.:.:|.|...|...| .:|:.|||:||
pombe   131 --------PS-LRRALASEDVEKIGPDPSVGAVLCGMDMHVTYLKYCMAFQYL-QDPNCAFLLTN 185

  Fly   202 RDAVHKYPSFCIPGTGAFVAGIEACSEREALEMGKPNPLVLEPFIKAEGLRTERTLMIGDCLKID 266
            :|:........:||:||....:...:.|:...:|||...::|..|.......::...:||.|..|
pombe   186 QDSTFPTNGKFLPGSGAISYPLIFSTGRQPKILGKPYDEMMEAIIANVNFDRKKACFVGDRLNTD 250

  Fly   267 VGFASNC---GMLSLLVGTGRYNNLSDVRLEKDRLPQPDFYLPRLGDL 311
            :.||.|.   |.|.:|.|..:...:    ||||....||:|:..|..|
pombe   251 IQFAKNSNLGGSLLVLTGVSKEEEI----LEKDAPVVPDYYVESLAKL 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5577	NP_001303369.1	PGP_euk	25..311	CDD:273635	84/294 (29%)
		Hydrolase_6	27..132	CDD:290083	29/105 (28%)
		Hydrolase_like	234..311	CDD:289983	24/79 (30%)
pho2	NP_596255.1	NagD	11..298	CDD:223720	87/304 (29%)
		Hydrolase_6	21..123	CDD:290083	29/105 (28%)
		Hydrolase_like	217..294	CDD:289983	24/80 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	57	1.000	Domainoid score	I3111
eggNOG	1	0.900	-	-		E1_COG0647
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	169	1.000	Inparanoid score	I1198
OMA	1	1.010	-	-		QHG60740
OrthoFinder	1	1.000	-	-		FOG0000783
OrthoInspector	1	1.000	-	-		otm47201
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.830