Protein Alignment Grd and Gabrg3

DIOPT Version :9

• Sequence 1: NP_524131.1
• Gene: Grd / 39984
• FlyBaseID: FBgn0001134
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_077346.3
• Gene: Gabrg3 / 79211
• RGDID: 621735
• Length: 467
• Species: Rattus norvegicus
• Alignment Length: 630
• Identity: 194/630 - (30%)
• Similarity: 275/630 - (43%)
• Gaps: 175/630 - (27%)

  Fly    47 LLMLCIYPNAWPWSIGPGSGPFSVSADSIKGRGDTHRLGEMGTSLSSSLPSSW-LTQSNNHANIS 110
            ||:||::           ||..:.|           |..|...|..|.....| |...:...:::
  Rat     6 LLLLCLF-----------SGLHARS-----------RRVEEDDSEDSPSNQKWVLAPKSQDTDVT 48

  Fly   111 ELLDNLLRGYDNSIRPDFGGPPATIEVDIMVRSMGPISEVDMTYSMDCYFRQSWVDKRLAFEGAQ 175
            .:|:.|||.||..:|||.|..|..|:|||.|.|:||:|.::|.|.:|.:|.|:|.|.||.|....
  Rat    49 LILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTDSRLRFNSTM 113

  Fly   176 DTLALSVSMLARIWKPDTYFYNGKQSYLHTITTPNKFVRIYQNGRVLYSSRLTIKAGCPMNLADF 240
            ..|.|:.:|:..||.|||.|.|.|.:..|.|||||:.:||:.:|::||:.||||.|.|.:.|.:|
  Rat   114 KILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLRLTINAECQLQLHNF 178

  Fly   241 PMDIQKCPLKFGSFGYTTSDVIYRWNKERPPVAIAEDMKLSQFDLVDCPAGNLTDIVYKAAAPRP 305
            |||...|||.|.|:||...::||||.|.....|..:..:|.|||.:..
  Rat   179 PMDAHACPLTFSSYGYPKEEMIYRWRKNSVEAADQKSWRLYQFDFMGL----------------- 226

  Fly   306 QRRPFNNKDPPRPTSKVMTTFAGPAAKNQHVRGTGLKLDKGAFGTGRDATGGSGSTTGLSGTITL 370
                       |.|::::||.||
  Rat   227 -----------RNTTEIVTTSAG------------------------------------------ 238

  Fly   371 ETNHPSEYSMLMVNFHLQRHMGNFLIQVYGPCCLLVVLSWVSFWLNREATADRVSLGITTVLTMT 435
                  :|.::.:.|.|.|.||.|.||.|.||.|.|||||||||:.::||..|.:||||||||||
  Rat   239 ------DYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTTLGITTVLTMT 297

  Fly   436 FLGLEARTDLPKVSYPTALDFFVFLSFGFIFATILQFAVVHYYTKYGSGECYFIIEELDSESGES 500
            .|...||..||:|||.||:|.||.:.|.|:||.::::|.::||:     .|      ......:.
  Rat   298 TLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATLNYYS-----SC------RKPTIRKK 351

  Fly   501 ETEPLTSDFRGSTESKIYEVIPLSMCAISM-PPPPTRLGMLTSRNRRPRNRRHGLWSMKLLGLFD 564
            :|..|..|.......:|....|.:...:.| ||||.   |:|..|           ||.
  Rat   352 KTSLLHPDSTRWIPDRISLQAPSNYSLLDMRPPPPV---MITLNN-----------SMY------ 396

  Fly   565 WRRRRKPPRADSDEDEDDEQTQLRANEAPTTSAAAAAAQAAAQAARISPPTGGRRRMSY---YRR 626
            |:           |.||                           ..:.....|:...|:   |..
  Rat   397 WQ-----------EFED---------------------------TCVYECLDGKDCQSFFCCYEE 423

  Fly   627 EEMEARRKGKRTPQYNSVSKIDRASRIVFPLLFILINVFYWYGYL 671
            .:..:.|:|:   .:..||::|..||:.||..|:|.|:.||.|||
  Rat   424 CKSGSWRRGR---IHIDVSELDSYSRVFFPTSFLLFNLVYWVGYL 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grd	NP_524131.1	Neur_chan_LBD	110..326	CDD:280998	83/215 (39%)
		LIC	111..670	CDD:273305	178/562 (32%)
		Neur_chan_memb	398..667	CDD:280999	81/272 (30%)
Gabrg3	NP_077346.3	Neur_chan_LBD	48..253	CDD:280998	90/280 (32%)
		LIC	50..464	CDD:273305	178/561 (32%)
		Neur_chan_memb	260..461	CDD:280999	81/272 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	199	1.000	Domainoid score	I2964
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1057372at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X127
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.110