Protein Alignment Grd and gabrg2

DIOPT Version :9

• Sequence 1: NP_524131.1
• Gene: Grd / 39984
• FlyBaseID: FBgn0001134
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: XP_031754595.1
• Gene: gabrg2 / 779514
• XenbaseID: XB-GENE-5949005
• Length: 505
• Species: Xenopus tropicalis
• Alignment Length: 673
• Identity: 193/673 - (28%)
• Similarity: 274/673 - (40%)
• Gaps: 236/673 - (35%)

  Fly    59 WSIGPGSGPFSVSADSIKGRGDTHRLGEM---------GTSLSSS-------------------- 94
            |....|:.||:... |.:| |:|.  |||         ..:||:|
 Frog     7 WGGHDGTIPFATKT-SDRG-GETR--GEMRSPKKPNSGNDALSASAFCHRKMIVRVLLILSFIQC 67

  Fly    95 -----------LPS--SWLTQSNNHAN-ISELLDNLLRGYDNSIRPDFGGPPATIEVDIMVRSMG 145
                       .||  :||.....|.| ::.:|:.||:||||.:|||.|..|..|..|:.|.|:|
 Frog    68 SFQKDDEDYEDAPSNNTWLLTRKFHDNDVTSILNGLLKGYDNKLRPDIGVKPTVIHTDMYVNSIG 132

  Fly   146 PISEVDMTYSMDCYFRQSWVDKRLAFEGAQDTLALSVSMLARIWKPDTYFYNGKQSYLHTITTPN 210
            |::.::|.|::|.:|.|:|.|:||.|......|.|:.:|:.:||.|||:|.|.|::..|.|||||
 Frog   133 PVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPN 197

  Fly   211 KFVRIYQNGRVLYSSRLTIKAGCPMNLADFPMDIQKCPLKFGSFGYTTSDVIYRWNKERPPVAIA 275
            :.:||:.:|||||:.||||.|.|.:.|.:||||...|||:|.|:||...::||:|.:....|...
 Frog   198 RMLRIWNDGRVLYTLRLTIDAECQLQLHNFPMDEHSCPLEFSSYGYPKEEIIYQWKRSSVEVGDV 262

  Fly   276 EDMKLSQFDLVDCPAGNLTDIVYKAAAPRPQRRPFNNKDPPRPTSKVMTTFAGPAAKNQHVRGTG 340
            ...:|.||..|                                                     |
 Frog   263 RSWRLYQFSFV-----------------------------------------------------G 274

  Fly   341 LKLDKGAFGTGRDATGGSGSTTGLSGTITLETNHPSEYSMLMVNFHLQRHMGNFLIQVYGPCCLL 405
            |          |:.|....:|:|             :|.::.|.|.|.|.||.|.||.|.||.|:
 Frog   275 L----------RNTTEEVKTTSG-------------DYVVMTVYFDLSRRMGYFTIQTYIPCTLI 316

  Fly   406 VVLSWVSFWLNREATADRVSLGITTVLTMTFLGLEARTDLPKVSYPTALDFFVFLSFGFIFATIL 470
            |||||||||:|::|...|.|||||||||||.|...||..||||||.||:|.||.:.|.|:||.::
 Frog   317 VVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALM 381

  Fly   471 QFAVVHYYTKYGSGECYFIIEELDSESGESETEPLTSDFRGSTESKIYEVIPLSMCAISMPPPPT 535
            ::..:||:..
 Frog   382 EYGTLHYFVS------------------------------------------------------- 391

  Fly   536 RLGMLTSRNRRPRNRRHGLWSMKLLGLFDWRRRRKPPRADSDEDEDDEQTQLRANEAPTTSAAAA 600
                    ||:|...:.......||.:|.::                         |||......
 Frog   392 --------NRKPSKDKEKKKKNPLLWMFSFK-------------------------APTIDIRPR 423

  Fly   601 AAQAAAQAARISPPTGGRRRMSYYRREEMEAR-----------------RKGKRTPQYNSVSKID 648
            :|     ..:::..|..:.|...|..|.::.:                 |.|:   .:..|:|||
 Frog   424 SA-----TIQMNNATHLQERDEEYGYECLDGKDCASFFCCFEDCRTGAWRHGR---IHIRVAKID 480

  Fly   649 RASRIVFPLLFILINVFYWYGYL 671
            ..|||.||..|.|.|:.||..||
 Frog   481 SYSRIFFPTAFCLFNLVYWVSYL 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grd	NP_524131.1	Neur_chan_LBD	110..326	CDD:280998	78/215 (36%)
		LIC	111..670	CDD:273305	171/575 (30%)
		Neur_chan_memb	398..667	CDD:280999	75/285 (26%)
gabrg2	XP_031754595.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	203	1.000	Domainoid score	I2891
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1057372at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X127
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.110