Protein Alignment Grd and gabrr2a

DIOPT Version :9

• Sequence 1: NP_524131.1
• Gene: Grd / 39984
• FlyBaseID: FBgn0001134
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: XP_017207163.1
• Gene: gabrr2a / 751659
• ZFINID: ZDB-GENE-060825-164
• Length: 475
• Species: Danio rerio
• Alignment Length: 590
• Identity: 164/590 - (27%)
• Similarity: 257/590 - (43%)
• Gaps: 164/590 - (27%)

  Fly    88 GTSLSSSLPSSWLTQSNNHANISELLDNLLRGYDNSIRPDFGGPPATIEVDIMVRSMGPISEVDM 152
            ||||:...|.  :|:| ......:||.  :..:|.::||.||||...:.||:.|.|:..||||||
Zfish    42 GTSLAKKPPD--VTKS-RRLKTEQLLK--VDDHDFTMRPAFGGPAIPVGVDVQVESLDSISEVDM 101

  Fly   153 TYSMDCYFRQSWVDKRLAFEGAQD-TLALSVSMLARIWKPDTYFYNGKQSYLHTITTPNKFVRIY 216
            .::|..|.|..|.|:||:|..:.: ::.....::.:||.||.:|.:.|:|::|..||.|..:|::
Zfish   102 DFTMTLYLRHYWKDERLSFTSSTNKSMTFDGRLVKKIWVPDVFFVHSKRSFIHDTTTENIMLRVF 166

  Fly   217 QNGRVLYSSRLTIKAGCPMNLADFPMDIQKCPLKFGSFGYTTSDVIYRWNKERPPVAIAEDMKLS 281
            .:|.||||.|:|:.|.|.|:.:.||:|.|.|.|:..|:.||..|::..|......::|.|.:.||
Zfish   167 PDGHVLYSLRVTVTAACNMDFSRFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLSIDEKISLS 231

  Fly   282 QFDLVDCPAGNLTDIVYKAAAPRPQRRPFNNKDPPRPTSKVMTTFAGPAAKNQHVRGTGLKLDKG 346
            ||            ::.|          |:.      ||::
Zfish   232 QF------------LIQK----------FHT------TSRL------------------------ 244

  Fly   347 AFGTGRDATGGSGSTTGLSGTITLETNHPSEYSMLMVNFHLQRHMGNFLIQVYGPCCLLVVLSWV 411
            ||          .|:||.             |:.|.:||.|:||:..||:|.|.|..|:|:||||
Zfish   245 AF----------YSSTGW-------------YNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWV 286

  Fly   412 SFWLNREATADRVSLGITTVLTMTFLGLEARTDLPKVSYPTALDFFVFLSFGFIFATILQFAVVH 476
            |||::|.|...||||||||||||:.:.......:|:|||..|:|.::::||.|:|.::|::|.|:
Zfish   287 SFWIDRRAVPARVSLGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVN 351

  Fly   477 YYTKYGSGECYFIIEE-----LDSESGESETEPLTSDFRGSTESKIYEVIPLSMCAISMPPPPTR 536
            |.|         .::|     |...:...::.|.|                   |.:|    .||
Zfish   352 YLT---------TVQERRERKLRDRAVREQSLPCT-------------------CGMS----HTR 384

  Fly   537 LGMLTSRNRRPRNRRHGLWSMKLLGLFDWRRRRKPPRADSDEDEDDEQTQLRANEAPTTSAAAAA 601
            ..||                                  |....|.|..:.....|||........
Zfish   385 TMML----------------------------------DGTYSEADTNSLAGYTEAPMVHEEVVP 415

  Fly   602 AQAAAQAARISPPTGGRRRMSYYRREEMEARRKGKRTPQ-YNSVSKIDRASRIVFPLLFILINVF 665
            .:.......:|..:           |....::||.|..: ..:...||:.||::||..:|:.|:.
Zfish   416 EKQEHMVVHLSVSS-----------ESTNTKKKGIRALRIMQNTHAIDKYSRMIFPGAYIIFNLI 469

  Fly   666 YWYGY 670
            ||..|
Zfish   470 YWSVY 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grd	NP_524131.1	Neur_chan_LBD	110..326	CDD:280998	70/216 (32%)
		LIC	111..670	CDD:273305	156/565 (28%)
		Neur_chan_memb	398..667	CDD:280999	69/274 (25%)
gabrr2a	XP_017207163.1	LIC	43..474	CDD:273305	162/587 (28%)
		Neur_chan_LBD	60..266	CDD:280998	81/282 (29%)
		Neur_chan_memb	273..471	CDD:280999	69/274 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900