Protein Alignment Grd and Gabre

DIOPT Version :9

• Sequence 1: NP_524131.1
• Gene: Grd / 39984
• FlyBaseID: FBgn0001134
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_075579.1
• Gene: Gabre / 65191
• RGDID: 68320
• Length: 989
• Species: Rattus norvegicus
• Alignment Length: 606
• Identity: 162/606 - (26%)
• Similarity: 253/606 - (41%)
• Gaps: 184/606 - (30%)

  Fly    86 EMGTSLSSSLPSSWLTQSNNHANISELLDNLLRGYDNSIRPDFGGPPATIEVDIMVRSMGPISEV 150
            |:....::..|...||::      |::|:.:|..||:.:||..|..|..:.|.:.|.|:||||.:
  Rat   538 ELTADHTTERPRGKLTRA------SQILNTILSNYDHKLRPSIGEKPTVVTVKVFVNSLGPISIL 596

  Fly   151 DMTYSMDCYFRQSWVDKRLAFEGAQDTLALSVSMLARIWKPDTYFYNGKQSYLHTITTPNKFVRI 215
            ||.||:|..|.|:|.|:||.:....:||.|..::::::|.|||:|.|.|::..:.||.||:...|
  Rat   597 DMEYSIDIIFYQTWYDERLRYNDTFETLILHGNVVSQLWIPDTFFRNSKRTQEYDITIPNQMALI 661

  Fly   216 YQNGRVLYSSRLTIKAGCPMNLADFPMDIQKCPLKFGSFGYTTSDVIYRWNKERPPVAIAEDMKL 280
            :::|:|||:.|:||.|.|.:::.:||||...|||.|.||.|...::||:|...:..:......||
  Rat   662 HKDGKVLYTVRMTIDARCSLHMLNFPMDSHSCPLSFSSFSYDEHEMIYKWENFKLKIDAKNTWKL 726

  Fly   281 SQFDLVDCPAGNLTDIVYKAAAPRPQRRPFNNKDPPRPTSKVMTTFAGPAAKNQHVRGTGLKLDK 345
            .:||...  ..|.|:|:                ..|.....|||.|
  Rat   727 LEFDFTG--VNNKTEII----------------STPVGDFMVMTFF------------------- 754

  Fly   346 GAFGTGRDATGGSGSTTGLSGTITLETNHPSEYSMLMVNFHLQRHMGNFLIQVYGPCCLLVVLSW 410
                                                   |::.|..|..:.|.|.|..:..:|||
  Rat   755 ---------------------------------------FNVSRRFGFIVFQNYIPSSVTTMLSW 780

  Fly   411 VSFWLNREATADRVSLGITTVLTMTFLGLEARTDLPKVSYPTALDFFVFLSFGFIFATILQFAVV 475
            ||||:..||.|.|.|:|:::||||..||..:|.:.|:|||.|||||::.:.|...|.|:|:|.|:
  Rat   781 VSFWIKIEAAAARASVGVSSVLTMATLGTFSRKNFPRVSYLTALDFYIAICFVLCFCTLLEFTVL 845

  Fly   476 HYYTKYGSGECYFIIEELDSESGESETEPLTSDFRGSTESKIYEVIPLSMCAISMPPPPTRLGML 540
            ::.|       |..||.        :..|           |.|:.             ||.
  Rat   846 NFLT-------YNNIER--------QASP-----------KFYQF-------------PTN---- 867

  Fly   541 TSRNRRPRNRRHGLWSMKLLGLFDWRRRRKPPRADSDEDEDDEQTQLRANEAPTTSAAAAAAQAA 605
            :..|.|.|.|               .|.|...||.:.:.::....::...|           :.|
  Rat   868 SRANARTRAR---------------ARTRARARARARQQQEVFVCEIVTYE-----------ENA 906

  Fly   606 AQAARISPPTGGRRRMSYYRREEMEARRKGK-------------RTP--QYNS---------VSK 646
            .:..:.||.:         ||.:...||.|:             ..|  :.||         |.:
  Rat   907 EEGYQWSPRS---------RRPQCPWRRCGRSYVCFRVLRKYFCMVPGCEGNSWQRGRICIHVYR 962

  Fly   647 IDRASRIVFPLLFILINVFYW 667
            :|..||::||:.|...||.||
  Rat   963 LDNYSRVLFPITFFFFNVVYW 983

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grd	NP_524131.1	Neur_chan_LBD	110..326	CDD:280998	76/215 (35%)
		LIC	111..670	CDD:273305	157/581 (27%)
		Neur_chan_memb	398..667	CDD:280999	75/292 (26%)
Gabre	NP_075579.1	Neur_chan_LBD	555..760	CDD:280998	78/286 (27%)
		LIC	557..983	CDD:273305	155/579 (27%)
		Neur_chan_memb	769..983	CDD:280999	75/291 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1057372at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X127
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.110